Detail
RLID: |
RLID00027496 |
RNA Symbol: |
hsa-let-7b |
RNA Category: |
miRNA |
Organism: |
Homo sapiens |
Aliase: |
hsa-let-7bL |
Subcellular Localization: |
Localization |
Tissue |
Validated Method |
PMID |
Mitochondrion |
Myoblast |
In situ hybridization |
21637849 |
Description: In situ hybridization of pre-mir-302a, pre-let-7b and mir-365, using specific labelled locked nucleic acids and confocal microscopy, demonstrated that these miRNA were localized in mitochondria of human myoblasts. Strikingly, we also observed that two pre-miRNAs, pre-mir302a and pre-let-7b were located within mitochondria surrounding the nucleus (Figures 5E, F). The present study demonstrated for the first time the localization of pre-miRNA (pre-mir-302a, pre-let-7b) and miRNA in human mitochondria isolated from muscular cells.
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Other Subcellular Localization: