Detail
| RLID: | RLID00027496 |
| RNA Symbol: | hsa-let-7b |
| RNA Category: | miRNA |
| Organism: | Homo sapiens |
| Aliase: | hsa-let-7bL |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Mitochondrion | Myoblast | In situ hybridization | 21637849 |
| Description: In situ hybridization of pre-mir-302a, pre-let-7b and mir-365, using specific labelled locked nucleic acids and confocal microscopy, demonstrated that these miRNA were localized in mitochondria of human myoblasts. Strikingly, we also observed that two pre-miRNAs, pre-mir302a and pre-let-7b were located within mitochondria surrounding the nucleus (Figures 5E, F). The present study demonstrated for the first time the localization of pre-miRNA (pre-mir-302a, pre-let-7b) and miRNA in human mitochondria isolated from muscular cells. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |