Detail
| RLID: | RLID00012393 |
| RNA Symbol: | nanos1 |
| RNA Category: | mRNA |
| Organism: | Xenopus laevis |
| Aliase: | nos1, xcat-2, xcat2, xnos1 |
| Subcellular Localization: | |
| Localization | Tissue | Validated Method | PMID |
| Mitochondrion | Oocyte | In situ hybridization | 8948579 |
| Description: In the present study we analyzed the properties of the METRO pathway, which localizes Xlsirt, Xcat2, and Xwnt11 RNAs to a specific region of the vegetal cortex during stage 1 of oogenesis. A combination of methodologies involving both fixed material and living oocytes was used to analyze RNA localization. We show that in early diplotene pre-stage 1 oocytes (25-50 microm in diameter) both endogenous and injected exogenous METRO RNAs translocated to multiple mitochondrial aggregates (pre-mitochondrial clouds) that surround the germinal vesicle (GV). However, by early stage 1 (diplotene oocytes, 50-200 microm), all three of the RNAs discriminated between the different clouds and translocated exclusively within the METRO of a single mitochondrial cloud. | |||
Other Subcellular Localization:
| RLID | Localization | Tissue | Validated Method | PMID |