Detail

RLID: RLID00012024
RNA Symbol: KRAS
RNA Category: mRNA
Organism: Homo sapiens
Aliase: C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS1, KRAS2, NS, NS3, RALD, RASK2, KRAS
Sequence:
Homology: KRAS (Canis lupus familiaris )
Network:
Subcellular Localization:
Localization Tissue Validated Method PMID
Mitochondrion HDF cell Fluorescence in situ hybridization 16178658
Description: Unexpectedly, we found that both K-ras and GAPDH mRNAs colocalize with mitochondria. Extensive control studies are performed, including the use of fluorescence in-situ hybridization (FISH), negative-control beacons, and the detection of colocalization of 28S ribosomal RNA with the rough endoplasmic reticulum (ER), suggesting that the mRNA localization and colocalization patterns observed in our study are true and specific.

Other Subcellular Localization:

RLID Localization Tissue Validated Method PMID
RLID00012023 Ribosome Colon cancer cell Next-generation sequencing 24393600
RLID00039404 Nucleus HeLa cells 44k oligoarray 26151857
RLID00078208 chromatin K562 CSCD
RLID00078209 nucleoplasm K562 CSCD
RLID00078210 nucleus K562 CSCD
RLID00078211 exosome blood exoRBase
RLID00078212 exosome serum exoRBase 28521461