Detail
RLID: |
RLID00000105 |
RNA Symbol: |
HOTAIR |
RNA Category: |
lncRNA |
Organism: |
Homo sapiens |
Aliase: |
HOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Subcellular Localization: |
Localization |
Tissue |
Validated Method |
PMID |
Nucleus |
Embryonic stem cell |
qRT-PCR|Microarray |
22193719 |
Description: Figure 7: Neuronal lncRNAs act via diverse mechanisms. (A) Quantification of relative expression of lncRNAs in nuclear and cytoplasmic cell fractions. (B) Quantification of changes in hosted miRNAs in response to lncRNA_N2 knockdown. MiRNAs were quantified using Taqman miRNA qPCR. (C-E) RIP of lncRNAs with SUZ12 and REST antibodies. The interaction of HOTAIR with SUZ12 is a known interaction that serves as a positive control (Gupta et al, 2010). * and ** indicate P-values of <0.05 and <0.01, respectively. Data are collected from Figure 7.
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Other Subcellular Localization: