Basic Information:

  VIRBase ID:  

HHID00058604

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-451a:  MIMAT0001631          CEP43:  NM_194429     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-451a	CEP43
miRBase Accession/Entrez ID	MIMAT0001631	11116
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FGFR1OP//FOP

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-451a	rs1378754345 chr17:28861413    T/C rs778869519 chr17:28861415    G/A rs746801009 chr17:28861408    AGTAATGGTAACG/A rs747864207 chr17:28861417    A/C rs901867276 chr17:28861419    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CEP43	chr6:167423098(+) A-I      intronic chr6:167423055(+) A-I      intronic chr6:167423103(+) A-I      intronic chr6:167422948(+) A-I      intronic chr6:167432044(+) A-I      intronic chr6:167422624(+) A-I      intronic chr6:167427310(+) A-I      intronic chr6:167422851(+) A-I      intronic chr6:167427276(+) A-I      intronic chr6:167422493(+) A-I      intronic chr6:167422224(+) A-I      intronic chr6:167422113(+) A-I      intronic chr6:167419970(+) A-I      intronic chr6:167452735(+) A-I      intronic chr6:167446765(+) A-I      intronic chr6:167423226(+) A-I      intronic chr6:167446764(+) A-I      intronic chr6:167434290(+) A-I      intronic chr6:167434236(+) A-I      intronic chr6:167432088(+) A-I      intronic chr6:167423203(+) A-I      intronic chr6:167427413(+) A-I      intronic chr6:167423105(+) A-I      intronic chr6:167422487(+) A-I      intronic chr6:167434275(+) A-I      intronic chr6:167432005(+) A-I      intronic chr6:167427300(+) A-I      intronic chr6:167422162(+) A-I      intronic chr6:167434517(+) A-I      intronic chr6:167434385(+) A-I      intronic chr6:167427301(+) A-I      intronic chr6:167431978(+) A-I      intronic chr6:167419950(+) A-I      intronic chr6:167434325(+) A-I      intronic chr6:167423060(+) A-I      intronic chr6:167449329(+) A-I      intronic chr6:167422145(+) A-I      intronic chr6:167423166(+) A-I      intronic chr6:167422465(+) A-I      intronic chr6:167422625(+) A-I      intronic chr6:167422150(+) A-I      intronic chr6:167430690(+) A-I      intronic chr6:167422848(+) A-I      intronic chr6:167434293(+) A-I      intronic chr6:167422900(+) A-I      intronic chr6:167422008(+) A-I      intronic chr6:167434241(+) A-I      intronic chr6:167434470(+) A-I      intronic chr6:167434573(+) A-I      intronic chr6:167432064(+) A-I      intronic chr6:167452770(+) A-I      intronic chr6:167434238(+) A-I      intronic chr6:167419816(+) A-I      intronic chr6:167434276(+) A-I      intronic chr6:167422236(+) A-I      intronic chr6:167427346(+) A-I      intronic chr6:167429874(+) A-I      intronic chr6:167430744(+) A-I      intronic chr6:167422859(+) A-I      intronic chr6:167429882(+) A-I      intronic chr6:167434347(+) A-I      intronic chr6:167427207(+) A-I      intronic chr6:167432062(+) A-I      intronic chr6:167422943(+) A-I      intronic chr6:167419965(+) A-I      intronic chr6:167434235(+) A-I      intronic chr6:167422904(+) A-I      intronic chr6:167422073(+) A-I      intronic chr6:167455509(+) A-I      3'UTR chr6:167455557(+) A-I      3'UTR chr6:167455512(+) A-I      3'UTR chr6:167455429(+) A-I      3'UTR chr6:167455365(+) A-I      3'UTR chr6:167430601(+) A-I      intronic chr6:167427308(+) A-I      intronic chr6:167434317(+) A-I      intronic chr6:167434357(+) A-I      intronic chr6:167430623(+) A-I      intronic chr6:167419888(+) A-I      intronic chr6:167427314(+) A-I      intronic chr6:167432008(+) A-I      intronic chr6:167419925(+) A-I      intronic chr6:167430665(+) A-I      intronic chr6:167422694(+) A-I      intronic chr6:167423201(+) A-I      intronic chr6:167434306(+) A-I      intronic chr6:167434282(+) A-I      intronic chr6:167434190(+) A-I      intronic chr6:167422022(+) A-I      intronic chr6:167432079(+) A-I      intronic chr6:167429931(+) A-I      intronic chr6:167422887(+) A-I      intronic chr6:167427341(+) A-I      intronic chr6:167434239(+) A-I      intronic chr6:167422085(+) A-I      intronic chr6:167429791(+) A-I      intronic chr6:167434133(+) A-I      intronic chr6:167434211(+) A-I      intronic chr6:167434277(+) A-I      intronic chr6:167427309(+) A-I      intronic chr6:167422015(+) A-I      intronic chr6:167434141(+) A-I      intronic chr6:167423341(+) A-I      intronic chr6:167422095(+) A-I      intronic chr6:167422223(+) A-I      intronic chr6:167434210(+) A-I      intronic chr6:167434309(+) A-I      intronic chr6:167431979(+) A-I      intronic chr6:167430743(+) A-I      intronic chr6:167429985(+) A-I      intronic chr6:167434574(+) A-I      intronic chr6:167422799(+) A-I      intronic chr6:167427350(+) A-I      intronic chr6:167422820(+) A-I      intronic chr6:167434566(+) A-I      intronic chr6:167430548(+) A-I      intronic chr6:167434213(+) A-I      intronic chr6:167429879(+) A-I      intronic chr6:167423204(+) A-I      intronic chr6:167422205(+) A-I      intronic chr6:167422587(+) A-I      intronic chr6:167429772(+) A-I      intronic chr6:167423102(+) A-I      intronic chr6:167423124(+) A-I      intronic chr6:167434245(+) A-I      intronic chr6:167422822(+) A-I      intronic chr6:167434219(+) A-I      intronic chr6:167419892(+) A-I      intronic chr6:167430011(+) A-I      intronic chr6:167430024(+) A-I      intronic chr6:167422097(+) A-I      intronic chr6:167434379(+) A-I      intronic chr6:167434220(+) A-I      intronic chr6:167434221(+) A-I      intronic chr6:167432139(+) A-I      intronic chr6:167434237(+) A-I      intronic chr6:167434142(+) A-I      intronic chr6:167430564(+) A-I      intronic chr6:167434303(+) A-I      intronic chr6:167422877(+) A-I      intronic chr6:167422488(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-451a	Exosome Primary T lymphocytes     24356509 Exosome Plasma     29130611 Exosome Peripheral blood|Portal vein blood     30561106 Exosome Serum     18589210 Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438 Exosome Renal cancer cells     21670082 Exosome HCC cell line (Hep3B|HepG2|PLC/PRF/5)     21721029 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Plasma     24130905 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Blood|B lymphoblastoid cells|Endothelial cells|Lymphoma tissue|Mast cells     - Extracellular Vesicle Liposarcoma cell lines (Lipo224B|Lipo246|Lipo863|LPS141)|Preadipocytes     28588009 Extracellular vesicle HEK-293T cells     22849433 Extracellular vesicle Colon cancer cell line (LIM1863)     25330373 Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Liver resident stem cells|Mesenchymal stem cells     20668554 Microvesicle Plasma     23077538 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
	CEP43	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-451a
Interactor2: CEP43

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.