• Detail
  • Binding
  • Network
Detail:
Vhid: VHID00005662
Virus: Human cytomegalovirus(HCMV)
Host Species: Homo sapiens
ncRNA Source: Virus
ncRNA Category: miRNA
ncRNA Symbol: hcmv-mir-US25-1
Tissue: -
Expression Direction of ncRNA: -
Interactor in Virus or Host: Host
Interactor Category: mRNA
Interactor Symbol: H3F3B
Expression Direction of Interactor: Downregulation
Validated Method: -
PMID: 22568714
Detailed Description: Table2. Human CMV miRNAs and their functions. Inhibits HCMV IE1 gene expression, and acts as an immune response inhibitor to help viral replication.Inhibits HCMV IE1gene expression, and acts as an immune response inhibitor to help viral replication Specifically downregulates MICB expression during viral infection, leading to decreased binding of NKG2D and reduced killing by NK cells.
Select the mature miRNA of hcmv-mir-US25-1 and the transcript of H3F3B
Mature miRNA of hcmv-mir-US25-1:    Transcript of H3F3B:
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour
It needs some time to initialize of Cytoscape web tool, please wait a while. The Cytoscape web tool also needs the Flash Player installed and supported.

The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.

The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Binding page: representing the predicted binding sites.
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.