The Detail page: representing the detail information for virus-host related ncRNA interaction;
The Network page: representing the interaction sub-network of interacting ncRNA/Interactor.
- Detail
- Binding
- Network
| Detail: | |
| Vhid: | VHID00005607 |
|---|---|
| Virus: | Herpesvirus saimiri(HVS) |
| Host Species: | Callithrix jacchus |
| ncRNA Source: | Virus |
| ncRNA Category: | LncRNA |
| ncRNA Symbol: | HSUR1 |
| Tissue: | HeLa cell line |
| Expression Direction of ncRNA: | - |
| Interactor in Virus or Host: | Host |
| Interactor Category: | Protein |
| Interactor Symbol: | SMN1 |
| Expression Direction of Interactor: | - |
| Validated Method: | Purification and analysis of native SMN complex, Transient-transfection and immunoprecipitation of HSURs, Indirect immunofluorescence. |
| PMID: | 15632062 |
| Detailed Description: | HVS encodes seven small RNAs (HSURs) of unknown function. The HSURs acquire host Sm proteins and assemble Sm cores similar to those found on the spliceosomal small nuclear RNPs (snRNPs). Here we show that, like host snRNPs, HSURs use the SMN (survival of motor neurons) complex to assemble Sm cores. As shown in Fig.1B, HSURs 1, 3, 4, and 5 bound specifically and efficiently to the SMN complex. |
The 'First Node' or 'Second Node' option represents the sub-network of interacting ncRNA/Interactor with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting ncRNA/Interactor with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.