Basic Information
| RNALocate ID: | RLID:01001240 |
| RNA Symbol: | hsa-let-7e-5p |
| Localization: | Nucleus |
RNA Information
| RNA Name: | hsa-let-7e |
| RNA ID: | miRBase:MIMAT0000066 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22058130 |
| Tissue/Cell Line: | HeLa cells |
| Method: | Next-generation RNA sequencing |
| Description: | Here, we present a data set excluding these RNA before sequencing through locked nucleic acids (LNA), greatly increasing pre-miRNA sequence counts with no discernable effect on pre-miRNA or mature miRNA sequencing. Analysis of profiles generated in total, nuclear and cytoplasmic cell fractions reveals that pre-miRNAs are subject to a wide range of regulatory processes involving loci-specific 3'- and 5'-end variation entailing complex cleavage patterns with co-occurring polyuridylation. Data were collected from Supplementary Table S2, S3. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001230 | Cytoplasm | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001231 | Cytoplasm | Cell line (HeLa) | 21695135 |
| RLID:01001232 | Cytoplasm | HeLa cells | 22058130 |
| RLID:01001233 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001234 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01001235 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001236 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01001237 | Nucleolus | Myoblasts | 19628621 |
| RLID:01001238 | Nucleolus | Breast adenocarcinoma cells (MCF-7) | 24918059 |
| RLID:01001239 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:11000626 | Apoptotic body | Human umbilical vein endothelial cells | 19996457 |
| RLID:11000627 | Exosome | Primary ovarian tumor cells|Serum | 18589210 |
| RLID:11000628 | Exosome | Hetastatic gastric cancer cell line (AZ-P7a) | 20949044 |
| RLID:11000629 | Exosome | Breast cancer cell line (MCF-7) | 20976003 |
| RLID:11000630 | Exosome | Primary dendritic cells | 21505438 |
| RLID:11000631 | Exosome | Breast milk | 22211110 |
| RLID:11000632 | Exosome | Epidermal melanocytes (HEMa-LP) | 23056502 |
| RLID:11000633 | Exosome | Brain tissue | 23382797 |
| RLID:11000634 | Exosome | Plasma | 23663360 |
| RLID:11000635 | Exosome | K562 cells | 24460325 |
| RLID:11000636 | Exosome | Breast cancer cell lines (MCF-7|MDA-MB-231) | 24468161 |
| RLID:11000637 | Extracellular vesicle | HEK-293T cells | 22849433 |
| RLID:11000638 | Microvesicle | Plasma | 23077538 |
| RLID:11000639 | Microvesicle | Seminal plasma | 23539611 |
| RLID-D:11000005 | Exosome | Endothelial cells|Epithelial cells|Mast cells|Seminal fluid | |
| RLID-D:11000265 | Microvesicle | Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-let-7e-5p | Diffuse large b cell lymphoma | MNDR-E-MI-01439 |
| MNDR | hsa-let-7e-5p | Splenic marginal zone lymphoma | MNDR-E-MI-01440 |
| MNDR | hsa-let-7e-5p | Colorectal adenoma | MNDR-E-MI-01441 |
| MNDR | hsa-let-7e-5p | Oral squamous cell carcinoma | MNDR-E-MI-01442 |
| MNDR | hsa-let-7e-5p | Lymphoma non-hodgkin | MNDR-E-MI-01443 |
| MNDR | hsa-let-7e-5p | Estrogen-receptor positive breast cancer | MNDR-E-MI-01444 |
| MNDR | hsa-let-7e-5p | Estrogen-receptor negative breast cancer | MNDR-E-MI-01445 |
| MNDR | hsa-let-7e-5p | Progesterone-receptor positive breast cancer | MNDR-E-MI-01446 |
| MNDR | hsa-let-7e-5p | Progesterone-receptor negative breast cancer | MNDR-E-MI-01447 |
| MNDR | hsa-let-7e-5p | Breast cancer luminal | MNDR-E-MI-01448 |
| MNDR | hsa-let-7e-5p | Prostate cancer | MNDR-E-MI-01449 |
| MNDR | hsa-let-7e-5p | Gastric cancer | MNDR-E-MI-01450 |
| MNDR | hsa-let-7e-5p | Gastric lymphoma | MNDR-E-MI-01451 |
| MNDR | hsa-let-7e-5p | Alzheimer disease | MNDR-E-MI-01452 |
| MNDR | hsa-let-7e-5p | Dysautonomia familial | MNDR-E-MI-01453 |
| MNDR | hsa-let-7e-5p | Head and neck cancer | MNDR-E-MI-01454 |
| MNDR | hsa-let-7e-5p | Leukemia | MNDR-E-MI-01455 |
| MNDR | hsa-let-7e-5p | Cardiovascular disease | MNDR-E-MI-01456 |
| MNDR | hsa-let-7e-5p | Lung cancer | MNDR-E-MI-01457 |
| MNDR | hsa-let-7e-5p | Metabolic syndrome x | MNDR-E-MI-01458 |
| MNDR | hsa-let-7e-5p | Parkinson disease | MNDR-E-MI-01459 |
| MNDR | hsa-let-7e-5p | Colonic adenomas | MNDR-E-MI-01460 |
| MNDR | hsa-let-7e-5p | Basal-like breast cancer | MNDR-E-MI-01461 |
| MNDR | hsa-let-7e-5p | Thyroid cancer | MNDR-E-MI-01462 |
| MNDR | hsa-let-7e-5p | Pancreatic cancer | MNDR-E-MI-01463 |
| MNDR | hsa-let-7e-5p | Melanoma | MNDR-E-MI-01464 |
| MNDR | hsa-let-7e-5p | Nephroblastoma | MNDR-E-MI-01465 |
| MNDR | hsa-let-7e-5p | Colon cancer | MNDR-E-MI-01466 |
| MNDR | hsa-let-7e-5p | Ischemic attack transient | MNDR-E-MI-01467 |
| MNDR | hsa-let-7e-5p | Colon adenocarcinoma | MNDR-E-MI-01468 |
| MNDR | hsa-let-7e-5p | Familial ovarian cancer | MNDR-E-MI-01469 |
| MNDR | hsa-let-7e-5p | Prostate adenocarcinoma | MNDR-E-MI-01470 |
| MNDR | hsa-let-7e-5p | Carcinoma ductal breast | MNDR-E-MI-01471 |
| MNDR | hsa-let-7e-5p | Glioblastoma | MNDR-E-MI-01472 |
| MNDR | hsa-let-7e-5p | Malignant glioma | MNDR-E-MI-01473 |
| MNDR | hsa-let-7e-5p | Chordoma | MNDR-E-MI-01474 |
| MNDR | hsa-let-7e-5p | Amyotrophic lateral sclerosis | MNDR-E-MI-01475 |
| MNDR | hsa-let-7e-5p | Temporal lobe epilepsy | MNDR-E-MI-01476 |
| MNDR | hsa-let-7e-5p | Osteosarcoma | MNDR-E-MI-01477 |
| MNDR | hsa-let-7e-5p | Liver cancer | MNDR-E-MI-01478 |
| MNDR | hsa-let-7e-5p | Uterine cancer | MNDR-E-MI-01479 |
| MNDR | hsa-let-7e-5p | Cervical adenocarcinoma | MNDR-E-MI-01480 |
| MNDR | hsa-let-7e-5p | Gastric adenocarcinoma | MNDR-E-MI-01481 |
| MNDR | hsa-let-7e-5p | Lung squamous cell carcinoma | MNDR-E-MI-01482 |
| MNDR | hsa-let-7e-5p | Lung adenocarcinoma | MNDR-E-MI-01483 |
| MNDR | hsa-let-7e-5p | Adrenocortical cancer | MNDR-E-MI-01484 |
| MNDR | hsa-let-7e-5p | Thyroid carcinoma | MNDR-E-MI-01485 |
| MNDR | hsa-let-7e-5p | Pancreatic adenocarcinoma | MNDR-E-MI-01486 |
| MNDR | hsa-let-7e-5p | Kidney renal clear cell carcinoma | MNDR-E-MI-01487 |
| MNDR | hsa-let-7e-5p | Kidney renal papillary cell carcinoma | MNDR-E-MI-01488 |
| MNDR | hsa-let-7e-5p | Renal clear cell carcinoma | MNDR-E-MI-01489 |
| MNDR | hsa-let-7e-5p | Biliary tract cancer | MNDR-E-MI-01490 |
| MNDR | hsa-let-7e-5p | Cholangiocarcinoma | MNDR-E-MI-01491 |
| MNDR | hsa-let-7e-5p | Esophageal cancer | MNDR-E-MI-01492 |
| MNDR | hsa-let-7e-5p | Liver cirrhosis | MNDR-E-MI-01493 |
| MNDR | hsa-let-7e-5p | Synovial sarcoma | MNDR-E-MI-01494 |
| MNDR | hsa-let-7e-5p | Head and neck squamous cell carcinoma | MNDR-E-MI-01495 |
| MNDR | hsa-let-7e-5p | Adenoma | MNDR-E-MI-01496 |
| MNDR | hsa-let-7e-5p | Breast invasive carcinoma | MNDR-E-MI-01497 |
| MNDR | hsa-let-7e-5p | Early hepatocellular carcinoma | MNDR-E-MI-01498 |
| MNDR | hsa-let-7e-5p | Familiar ovarian carcinoma | MNDR-E-MI-01499 |
| MNDR | hsa-let-7e-5p | B-cell lymphoma | MNDR-E-MI-01500 |
| MNDR | hsa-let-7e-5p | Rheumatoid arthritis | MNDR-E-MI-01501 |
| MNDR | hsa-let-7e-5p | T-cell leukemia | MNDR-E-MI-01502 |
| MNDR | hsa-let-7e-5p | Retinoblastoma | MNDR-E-MI-01503 |
| MNDR | hsa-let-7e-5p | Neuroblastoma | MNDR-E-MI-01504 |
| MNDR | hsa-let-7e-5p | Hodgkin lymphoma | MNDR-E-MI-01505 |
| MNDR | hsa-let-7e-5p | Burkitt lymphoma | MNDR-E-MI-01506 |
| MNDR | hsa-let-7e-5p | Tonsil cancer | MNDR-E-MI-01507 |
| MNDR | hsa-let-7e-5p | Neuromyelitis optica | MNDR-E-MI-01508 |
| MNDR | hsa-let-7e-5p | Acute myelogenous leukemia | MNDR-E-MI-01509 |
| MNDR | hsa-let-7e-5p | Colorectal cancer | MNDR-E-MI-01510 |
| MNDR | hsa-let-7e-5p | Nasopharynx carcinoma | MNDR-E-MI-01511 |
| MNDR | hsa-let-7e-5p | Multiple myeloma | MNDR-E-MI-01512 |
| MNDR | hsa-let-7e-5p | Nasopharyngeal cancer | MNDR-E-MI-01513 |
| MNDR | hsa-let-7e-5p | Prostatic neoplasms | MNDR-E-MI-01514 |
| MNDR | hsa-let-7e-5p | Epstein-barr virus infections | MNDR-E-MI-01515 |
| MNDR | hsa-let-7e-5p | Cerebral hemorrhage traumatic | MNDR-E-MI-01516 |
| MNDR | hsa-let-7e-5p | Intracranial hemorrhage hypertensive | MNDR-E-MI-01517 |
| MNDR | hsa-let-7e-5p | Stroke | MNDR-E-MI-01518 |
| MNDR | hsa-let-7e-5p | Stroke lacunar | MNDR-E-MI-01519 |
| MNDR | hsa-let-7e-5p | Duke C | MNDR-E-MI-01520 |
| MNDR | hsa-let-7e-5p | Low grade dysplastic nodule | MNDR-E-MI-01521 |
| MNDR | hsa-let-7e-5p | Solid-pseudopapillary neoplasm of pancreas | MNDR-E-MI-01522 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | ACVR1B | Homo sapiens | RR00038913 |
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