ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-93

MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0004509 hsa-miR-93-3p	ACUGCUGAGCUAGCACUUCCCG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.
MI0000095	MIPF0000001	CUGGGGGCUCCAAAGUGCUGUUCGUGCAGGUAGUGUGAUUACCCAACCUACUGCUGAGCUAGCACUUCCCGAGCCCCCGG	MIMAT0000093 hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Mourelatos et al. identified two copies of this sequence mapping tochromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 .Subsequent genome assemblies suggest the presence of only one miR-93 locuson chromosome 7. The mature sequence shown here represents the mostcommonly cloned form from large-scale cloning studies . The 5' end ofthe miRNA may be offset with respect to previous annotations.

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

CNOT1,DZIP3,DPP8,ACTR2,LIMA1,DIDO1,ABR,KLB,KAT2B,TRIO,FDXACB1,KIAA1715,FASN,ARID4B,EIF4H
more » CNOT1,DZIP3,DPP8,ACTR2,LIMA1,DIDO1,ABR,KLB,KAT2B,TRIO,FDXACB1,KIAA1715,FASN,ARID4B,EIF4H,TYW5,LAPTM4B,EPHA7,N4BP1,KIAA1147,MAFG,NCAPD2,RBM23,WAC,MLL2,PTPN9,HSP90AB1,FBXL5,ARL9,PITRM1,ATP5B,EZH2,RMND5B,HUWE1,UBE3B,MED12L,SPTAN1,ZC3H18,FKBP7,EIF4A1,SLC19A1,PHC3,FAM3C,KLHDC3,FAM129A,SND1,TRIM65,BTG3,SLC25A23,RYBP,TSN,TBC1D20,PBRM1,VEGFA,USP21,KLF11,CENPF,NPEPPS,ZIC2,RPL5,C1QBP,APBB2,PTENP1,TMEM168,PHLPP2,BTBD10,TARDBP,GANAB,KDM3B,PARP1,COQ2,DVL3,NCSTN,PARD3,BMPR2,TMX3,STYX,UNC45A,ZNF417,UBE2J1,RBM15B,PPAN,TAF4,PGAM1,ZBTB33,NUP188,RPL9,H3F3B,C16orf70,SLC35A4,CYCS,RNF34,LRRC34,OXA1L,PYGL,ZC3H7A,CCT8,SAMD8,TMEM100,RABGAP1,FAM82A2,KIAA1826,TRIM28,MCM7,ADSL,GPR137C,SH3GLB1,CBX3,DCTN6,TMEM127,GPATCH2,ICAM4,DDX5,TAF6,PURA,ACSL1,LRRC58,UBE2Q1,MPP5,SF3B2,CDC42,GOT2,FYCO1,DNMT3B,NUCKS1,ITPA,LRBA,TYSND1,EIF4ENIF1,ZBTB41,SMG7,UBE2O,FAM89B,C1orf9,PRKCI,AKAP11,C5orf41,MYO19,MAN1C1,NUBP1,HERPUD1,DAPK3,CSAG1,PCID2,ZNF805,GSG2,ARSJ,UBXN2A,RRN3,CAP1,SPTBN1,TLK2,ATXN1,TOLLIP,SAMD12,SURF4,FKBP5,DCTN4,STC2,PSMD11,STAT3,SYBU,UPF1,ZMIZ1,STAT5B,NUP160,NUP153,ELAC2,PSMD13,GRID2IP,EZH1,WNK1,SQSTM1,KIAA1671,FMNL2,SERBP1,PRRC2A,IP6K1,MPG,PUF60,WDR33,ANKRD27,MON1B,CCND1,RNF220,TMEM194A,GRSF1,CASP2,ANAPC7,CCNG2,RNF145,LRIG3,FKBP3,CDC16,SLC9A6,MAD2L1,MCM3,SLC5A3,IPO5,ARHGAP1,HNRNPM,QTRTD1,RBBP7,PDE3B,C5orf22,HEG1,XBP1,ARFGAP3,HK1,SNAPIN,PPP1R15B,EPHA4,AP2A2,TRAM1,HARS,PLEKHA1,LHFPL2,RAB5B,GNB4,RAB11FIP1,ACTB,PPTC7,ZBTB7A,SUCLA2,EIF2AK1,SUPT5H,EIF4G2,REV3L,H1F0,HEYL,CLN8,ARCN1,MIDN,MAP2K1,RPL30,ZADH2,ZNF295,UBR1,MYO1E,EGLN3,FAR1,CTC1,CDC20,YWHAQ,WDR77,ATP1A1,TBCC,MAP3K13,FAM50A,DMKN,HIST3H2A,ZNF202,SGTB,TPD52L2,DUSP8,TNFRSF21,SIN3A,OTUB1,NONO,ZNF217,MAPRE1,BAG2,TGFBR2,ATIC,EEF1D,ASF1A,PHF10,KANSL3,ARIH2,E2F3P1,PGP,CSNK1G1,TCOF1,TRPC4AP,IRF1,PPP1R13B,TRIP10,APLP2,ZCCHC14,RFC3,NIN,SRPK1,PRPF8,IKBKAP,POGK,CCNY,PLEKHG4,UBE2M,MARK2,POLR2A,GNA12,PGM2L1,FEM1C,UBN1,C18orf32,PRKACB,TRIM8,SPATA2,CPPED1,SCN1A,PRUNE2,KIAA1191,EAPP,CBR1,YOD1,ZNF706,TOMM20,DDX39B,FAM210A,ZSWIM1,SUV420H1,RAB34,LOXL1,KLHDC2,VAMP7,HNRNPUL1,TULP3,EIF2C1,HDDC2,RPL27,SAMD4B,ARHGAP32,NAA30,MFN2,CUL2,GPN3,AP1G1,FUK,MAPRE3,NPM1,ZNF44,USF1,FOXJ3,CRY2,MOB1A,TIAM1,SMG6,PFAS,PDRG1,REEP3,C11orf41,DHX9,SP7,CCDC88C,MYLIP,SFXN5,MLLT6,NUPL1,ALS2,INPP5D,CD164,XYLT2,DHX30,LYST,GAPDH,ACTN1,CDC37L1,DMWD,MZT1,FAM193B,GCAT,RRP12,ZFP91,RPA2,ITGB8,JMJD8,RAB8B,RGPD5,ATP6,PPM1H,OSR1,NFKBIL1,HIST1H3B,CDKN1A,PAPOLA,SRSF2,ARL1,HSPA5,EGR2,MTPAP,KPNA2,ACIN1,TUT1,SC5DL,DCAF8,SCRIB,HAUS8,SH3PXD2A,TNKS1BP1,UBA2,VAT1,NDEL1,DSTYK,BNIP2,SMAD4,ANKFY1,ASB1,VARS,PI4KA,YTHDC1,SEC23IP,E2F1,IGF2,LUZP1,LDLR,TEX261,MYCBP,FRS2,MAP3K4,DNAJC5,ZNF143,SREBF1,BCL2L11,CNOT4,CAV2,ANKRD52,WDR1,VLDLR,NFIB,AP1AR,MTSS1L,C1orf21,HOOK1,VMA21,SPRED1,HCCS,CD46,EPHB4,ATP6V1G2-DDX39B,IFT140,KIAA0494,MED21,IBA57,PBX3,EIF1AD,RPS6KA5,TPRG1L,PAPD7,CALCOCO2,NCOA4,GPS1,ZNF76,F3,CERS2,DDX46,STK11,ZNF384,PPP1R12A,NOB1,NUP205,WASH3P,SPOPL,LRP3,PDZD11,THUMPD3,PDS5A,SH3BP4,PFDN2,HIST2H3A,NR2C2AP,KIAA1279,ZNF813,NBEAL2,CDHR1,IKZF4,ENO2,CIT,RIF1,SOWAHC,TAX1BP1,WDR26,MYO9B,SEL1L3,RUNX3,RND3,HACL1,GLUD1,WIZ,ZNF148,TMEM42,ICMT,ZBTB3,FBXL3,LATS2,NTHL1,NUAK1,JUN,MCM5,ZIC5,MAPK9,ARPC2,TESK2,NUP107,DCTN1,GARS,ACPL2,SMC1A,ZNF264,SGMS1,TRAK1,B2M,IRAK1,FAM98A,HYOU1,KLHL28,PSMD4,ZNF180,POLE,PTPN4,GPR162,NUFIP2,SEC16A,HPS1,PIK3R2,UBAP2L,FOXRED2,MICALL1,PBXIP1,BAZ2A,KATNAL1,ATG16L1,STX16,TSG101,ITPRIP,RB1,DAZAP1,C3orf38,TAF8,TLE3,ZNFX1,ANKRD29,ARHGAP12,CRELD2,FIGNL1,MYPOP,SCAP,ELAVL1,KLF9,FAH,HMMR,RAB13,GRAMD1A,BIRC5,SET,OTUD4,PKD2,ENAH,NHLRC3,UBR5,ANAPC5,FAM57A,TP53INP1,CCDC47,RUNDC3B,UBE2R2,ZC3H12C,ADARB1,BAP1,SERTAD2,ACLY,C6orf62,PPP6R2,YY1,MRPL49,ADAR,SEC23A,EPB49,FYN,ZNF703,FAM120A,RHEBL1,EEF1A1,GLI3,PTEN,TAGLN2,UQCRC1,CTTNBP2NL,NFE2L2,LRRC41,HDGF,DYRK2,LAMA4,SLC29A2,NBPF15,RNF44,SUFU,CAPRIN2,MED13L,CCDC22,ERLIN2,HIST2H4B,TUSC2,RPL7A,ATAD5,FCHO2,UTP14C,EXOC4,AAGAB,NUP62,MAP7,ATP5SL,LIX1L,DOCK5,ADRM1,ARHGEF33,PAMR1,POMGNT1,C1orf63,RRAS2,TELO2,NASP,NR4A1,UBE2L3,PRRG1,GRB2,ARFGAP1,NACC2

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05200	Pathways in cancer	JUN,E2F1,STAT3,NCOA4,BIRC5,PTENP1,CDKN1A,VEGFA,TGFBR2,MAPK9,CCND1,PTEN,DVL3,MAP2K1,SUFU,RB1,HSP90AB1,GLI3,CYCS,CUL2,GRB2,STAT5B,SMAD4,LAMA4,DAPK3,EGLN3,PIK3R2,CDC42,	2.52E-4
hsa04110	Cell cycle	CCND1,SMC1A,MCM3,CDC16,YWHAQ,E2F1,MCM5,MCM7,RB1,CDKN1A,CDC20,ANAPC7,ANAPC5,SMAD4,MAD2L1,	2.53E-4
hsa05212	Pancreatic cancer	MAPK9,CCND1,E2F1,VEGFA,STAT3,MAP2K1,SMAD4,TGFBR2,RB1,CDC42,PIK3R2,	3.52E-4
hsa04120	Ubiquitin mediated proteolysis	CDC16,UBA2,UBE2Q1,UBR5,HUWE1,UBE2R2,UBE2L3,CUL2,UBE3B,CDC20,UBE2O,ANAPC7,ANAPC5,UBE2M,UBE2J1,	6.54E-4
hsa05219	Bladder cancer	CCND1,E2F1,VEGFA,RPS6KA5,MAP2K1,RB1,CDKN1A,DAPK3,	9.14E-4

hsa05210	Colorectal cancer	JUN,MAPK9,CCND1,CYCS,DVL3,GRB2,MAP2K1,BIRC5,SMAD4,TGFBR2,PIK3R2,	1.21E-2
hsa04914	Progesterone-mediated oocyte maturation	MAPK9,CDC16,PDE3B,IGF2,MAP2K1,ANAPC7,PRKACB,ANAPC5,HSP90AB1,MAD2L1,PIK3R2,	1.46E-2
hsa04910	Insulin signaling pathway	MAPK9,HK1,PDE3B,MAP2K1,PRKACB,IGF2,FASN,GRB2,PYGL,TRIP10,SREBF1,PRKCI,PIK3R2,INPP5D,	1.76E-2
hsa05220	Chronic myeloid leukemia	CCND1,E2F1,GRB2,MAP2K1,STAT5B,SMAD4,TGFBR2,RB1,CDKN1A,PIK3R2,	2.01E-2
hsa05215	Prostate cancer	CCND1,IGF2,PTEN,E2F1,GRB2,MAP2K1,PTENP1,RB1,CDKN1A,HSP90AB1,PIK3R2,	6.45E-2
hsa04510	Focal adhesion	JUN,CCND1,MAPK9,PTEN,MAP2K1,PTENP1,CAV2,VEGFA,GRB2,ITGB8,PPP1R12A,LAMA4,FYN,ACTB,ACTN1,CDC42,PIK3R2,	9.30E-2
hsa05214	Glioma	CCND1,PTEN,E2F1,GRB2,MAP2K1,PTENP1,RB1,CDKN1A,PIK3R2,	9.56E-2
hsa03030	DNA replication	MCM3,MCM5,MCM7,POLE,RFC3,RPA2,	1.10E-1
hsa05211	Renal cell carcinoma	JUN,VEGFA,GRB2,CUL2,MAP2K1,EGLN3,CDC42,PIK3R2,	1.65E-1
hsa04114	Oocyte meiosis	SMC1A,YWHAQ,CDC16,IGF2,MAP2K1,CDC20,ANAPC7,PRKACB,ANAPC5,MAD2L1,	2.38E-1
hsa04530	Tight junction	RAB13,PTEN,PTENP1,EXOC4,RRAS2,PRKCI,PARD3,ACTB,ACTN1,SPTAN1,CDC42,MPP5,	3.11E-1
hsa04722	Neurotrophin signaling pathway	JUN,MAPK9,YWHAQ,FRS2,GRB2,RPS6KA5,MAP2K1,IRAK1,CDC42,PIK3R2,	4.63E-1
hsa05218	Melanoma	CCND1,PTEN,E2F1,MAP2K1,PTENP1,RB1,CDKN1A,PIK3R2,	5.25E-1
hsa05223	Non-small cell lung cancer	CCND1,E2F1,GRB2,MAP2K1,RB1,PIK3R2,	5.36E-1
hsa05221	Acute myeloid leukemia	CCND1,STAT3,GRB2,MAP2K1,STAT5B,PIK3R2,	6.89E-1
hsa04520	Adherens junction	SMAD4,FYN,TGFBR2,PARD3,ACTB,ACTN1,CDC42,	7.23E-1
hsa04144	Endocytosis	AP2A2,LDLR,ARFGAP1,SH3GLB1,RAB5B,PRKCI,ARFGAP3,TGFBR2,PARD3,CDC42,TSG101,RAB11FIP1,	9.18E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0046907	intracellular transport	JUN,STX16,MFN2,NUP160,ENAH,SEC23IP,SNAPIN,ALS2,TRAK1,SEC23A,ICMT,KIAA1279,SET,SQSTM1,PRKCI,ANKRD27,RBM15B,MYO9B,MAP2K1,ATXN1,TRAM1,ARCN1,HOOK1,NUP107,NUP205,AP2A2,AP1G1,UPF1,ARL1,MYO1E,YWHAQ,TOMM20,C16orf70,ARFGAP3,SMG7,VAMP7,IPO5,RGPD5,SMG6,NDEL1,LYST,EXOC4,TRPC4AP,NPM1,KPNA2,CRY2,ARFGAP1,SPTBN1,GLI3,ZNF384,DDX39B,	2.09E-7
GO:0007049	cell cycle	CDC16,E2F1,KLHDC3,SUPT5H,DMWD,BIRC5,RIF1,MFN2,TLK2,PRUNE2,TSG101,LATS2,GSG2,MAP2K1,RB1,NCAPD2,PBRM1,EIF4G2,TP53INP1,CUL2,UPF1,ANAPC7,ANAPC5,MAD2L1,TUSC2,PAPD7,SMC1A,PSMD11,PKD2,RABGAP1,PSMD13,SH3BP4,PSMD4,MAPRE1,STK11,CDKN1A,MAPRE3,GPS1,NASP,CCND1,HAUS8,PDS5A,MCM3,MCM7,KAT2B,NPM1,KPNA2,POLE,APBB2,CENPF,CIT,DCTN1,TARDBP,UTP14C,CDC20,PARD3,CCNG2,	2.16E-7
GO:0022402	cell cycle process	PKD2,PSMD11,SMC1A,CDC16,PSMD13,KLHDC3,E2F1,DMWD,BIRC5,PSMD4,MAPRE1,STK11,CDKN1A,MFN2,MAPRE3,PRUNE2,TSG101,PDS5A,HAUS8,CCND1,KAT2B,LATS2,NPM1,KPNA2,MAP2K1,POLE,APBB2,RB1,CENPF,NCAPD2,CIT,PBRM1,EIF4G2,TP53INP1,DCTN1,TARDBP,CUL2,UTP14C,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.57E-6
GO:0051276	chromosome organization	EZH2,SMC1A,EZH1,SUPT5H,H1F0,UBN1,DNMT3B,SMG6,ASF1A,BAZ2A,HIST3H2A,TLK2,SET,NASP,HIST2H4B,RPS6KA5,SUV420H1,USP21,KAT2B,GSG2,NPM1,ARID4B,RB1,CENPF,NCAPD2,ACIN1,PBRM1,MLL2,HUWE1,H3F3B,TNKS1BP1,KDM3B,DAPK3,HIST1H3B,MAD2L1,HIST2H3A,PARP1,PAPD7,RBBP7,CBX3,	3.30E-6
GO:0044265	cellular macromolecule catabolic process	MPG,CDC16,CLN8,YOD1,UBE2Q1,LRRC41,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,RPA2,UBE2M,UBE2J1,TSG101,UBA2,EIF2C1,ASB1,UBR5,UBE2R2,BAP1,OTUB1,CUL2,UPF1,UBE3B,ANAPC7,FEM1C,ANAPC5,CNOT4,MAD2L1,PSMD11,PSMD13,PSMD4,SMG7,ARIH2,SMG6,LDLR,UBE2L3,FOXRED2,FBXL5,USP21,MYLIP,RNF34,ERLIN2,HUWE1,DZIP3,CYCS,NTHL1,CDC20,NCSTN,	8.38E-6

GO:0000278	mitotic cell cycle	SMC1A,PSMD11,CDC16,PSMD13,E2F1,BIRC5,PSMD4,MAPRE1,CDKN1A,MAPRE3,PDS5A,HAUS8,CCND1,LATS2,KPNA2,MAP2K1,POLE,RB1,CENPF,CIT,NCAPD2,PBRM1,DCTN1,CUL2,TARDBP,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.87E-5
GO:0016071	mRNA metabolic process	SMC1A,SF3B2,SMG7,HNRNPUL1,SMG6,VEGFA,DDX46,WDR77,ELAVL1,ADARB1,ADAR,RBM15B,HNRNPM,SRPK1,PUF60,NONO,RBM23,MTPAP,GRSF1,SERBP1,EIF2C1,YTHDC1,DHX9,PAPOLA,TARDBP,DDX5,UPF1,PRPF8,POLR2A,DDX39B,SRSF2,	1.87E-5
GO:0008104	protein localization	JUN,NUP188,RAB34,STX16,MFN2,NUP160,AP1AR,SEC23IP,SNAPIN,ALS2,OXA1L,TRAK1,SEC23A,ICMT,SQSTM1,PRKCI,EIF4ENIF1,NUP153,TSG101,SEC16A,ATG16L1,AAGAB,NUPL1,TRAM1,ARCN1,HOOK1,NUP107,NUP205,RAB11FIP1,AP2A2,AP1G1,RAB8B,NFKBIL1,NUP62,YWHAQ,RAB13,TOMM20,C16orf70,SH3GLB1,ARFGAP3,VAMP7,IPO5,RGPD5,LYST,RAB5B,NASP,EXOC4,TRPC4AP,NPM1,KPNA2,CRY2,ARFGAP1,SPTBN1,CENPF,GLI3,CDC42,	2.32E-5
GO:0022403	cell cycle phase	SMC1A,CDC16,PSMD13,KLHDC3,E2F1,DMWD,BIRC5,MAPRE1,CDKN1A,MAPRE3,PRUNE2,PDS5A,HAUS8,CCND1,LATS2,KPNA2,MAP2K1,POLE,RB1,CENPF,NCAPD2,CIT,PBRM1,DCTN1,TARDBP,CUL2,UTP14C,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	2.58E-5
GO:0009057	macromolecule catabolic process	MPG,CDC16,CLN8,YOD1,UBE2Q1,LRRC41,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,RPA2,UBE2J1,TSG101,UBA2,EIF2C1,ASB1,UBR5,UBE2R2,BAP1,OTUB1,CUL2,UPF1,UBE3B,PYGL,ANAPC7,FEM1C,ANAPC5,CNOT4,MAD2L1,PSMD11,PSMD13,PSMD4,SMG7,ARIH2,SMG6,LDLR,UBE2L3,FOXRED2,FBXL5,USP21,MYLIP,RNF34,ERLIN2,HUWE1,DZIP3,CYCS,NTHL1,CDC20,NCSTN,	2.84E-5
GO:0015031	protein transport	JUN,NUP188,RAB34,STX16,MFN2,NUP160,SEC23IP,SNAPIN,AP1AR,TRAK1,SEC23A,ICMT,PRKCI,EIF4ENIF1,NUP153,TSG101,SEC16A,ATG16L1,AAGAB,NUPL1,TRAM1,ARCN1,HOOK1,NUP107,NUP205,RAB11FIP1,AP2A2,AP1G1,RAB8B,NUP62,YWHAQ,RAB13,TOMM20,C16orf70,ARFGAP3,VAMP7,IPO5,RGPD5,LYST,RAB5B,NASP,EXOC4,TRPC4AP,NPM1,KPNA2,CRY2,ARFGAP1,SPTBN1,CENPF,GLI3,	3.05E-5
GO:0006913	nucleocytoplasmic transport	JUN,NPM1,KPNA2,CRY2,SPTBN1,ATXN1,IPO5,SMG7,NUP107,GLI3,NUP160,NUP205,SMG6,ZNF384,SET,UPF1,RBM15B,DDX39B,	3.50E-5
GO:0045184	establishment of protein localization	JUN,NUP188,RAB34,STX16,MFN2,NUP160,SEC23IP,SNAPIN,AP1AR,TRAK1,SEC23A,ICMT,PRKCI,EIF4ENIF1,NUP153,TSG101,SEC16A,ATG16L1,AAGAB,NUPL1,TRAM1,ARCN1,HOOK1,NUP107,NUP205,RAB11FIP1,AP2A2,AP1G1,RAB8B,NUP62,YWHAQ,RAB13,TOMM20,C16orf70,ARFGAP3,VAMP7,IPO5,RGPD5,LYST,RAB5B,NASP,EXOC4,TRPC4AP,NPM1,KPNA2,CRY2,ARFGAP1,SPTBN1,CENPF,GLI3,	3.91E-5
GO:0051169	nuclear transport	JUN,NPM1,KPNA2,CRY2,SPTBN1,ATXN1,IPO5,SMG7,NUP107,GLI3,NUP160,NUP205,SMG6,ZNF384,SET,UPF1,RBM15B,DDX39B,	4.13E-5
GO:0006325	chromatin organization	EZH2,EZH1,SUPT5H,H1F0,UBN1,DNMT3B,ASF1A,BAZ2A,HIST3H2A,TLK2,SET,NASP,HIST2H4B,KAT2B,USP21,SUV420H1,RPS6KA5,GSG2,NPM1,ARID4B,RB1,PBRM1,MLL2,HUWE1,H3F3B,KDM3B,DAPK3,HIST1H3B,HIST2H3A,RBBP7,CBX3,	7.03E-5
GO:0044257	cellular protein catabolic process	PSMD11,CDC16,PSMD13,CLN8,PSMD4,YOD1,ARIH2,UBE2Q1,UBE2L3,LRRC41,FOXRED2,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,UBE2J1,TSG101,FBXL5,UBA2,USP21,MYLIP,RNF34,ASB1,ERLIN2,UBR5,HUWE1,DZIP3,UBE2R2,BAP1,CUL2,OTUB1,UBE3B,CDC20,ANAPC7,FEM1C,ANAPC5,NCSTN,CNOT4,MAD2L1,	8.74E-5
GO:0010605	negative regulation of macromolecule metabolic process	JUN,SND1,PSMD11,YWHAQ,CDC16,SIN3A,PSMD13,CLN8,E2F1,STAT3,ZNF202,SUPT5H,ZNF148,NACC2,PSMD4,DNMT3B,IGF2,BAZ2A,KLF11,ZBTB7A,SET,RYBP,ADAR,RBM15B,TRIM28,TSG101,INPP5D,NPM1,EIF2C1,ATXN1,RB1,CENPF,ASB1,MYPOP,HSP90AB1,GLI3,FAM129A,PURA,PBXIP1,EIF2AK1,CDC20,ANAPC7,SMAD4,ANAPC5,MAD2L1,RBBP7,CBX3,	1.00E-4
GO:0000280	nuclear division	PDS5A,SMC1A,HAUS8,CDC16,LATS2,MAP2K1,BIRC5,MAPRE1,CENPF,NCAPD2,CIT,PBRM1,MAPRE3,DCTN1,TARDBP,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.00E-4
GO:0007067	mitosis	PDS5A,SMC1A,HAUS8,CDC16,LATS2,MAP2K1,BIRC5,MAPRE1,CENPF,NCAPD2,CIT,PBRM1,MAPRE3,DCTN1,TARDBP,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.00E-4
GO:0000279	M phase	SMC1A,CDC16,PSMD13,KLHDC3,DMWD,BIRC5,MAPRE1,MAPRE3,HAUS8,PDS5A,LATS2,KPNA2,MAP2K1,RB1,CENPF,CIT,NCAPD2,PBRM1,DCTN1,TARDBP,UTP14C,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.03E-4
GO:0008219	cell death	NUP62,JUN,C3orf38,CLN8,BAG2,E2F1,SCRIB,SH3GLB1,TAX1BP1,BIRC5,PTENP1,BNIP2,ALS2,IGF2,KLF11,PLEKHG4,RYBP,SQSTM1,PRUNE2,BCL2L11,F3,DYRK2,INPP5D,SGMS1,PTEN,PUF60,GARS,ATXN1,RNF34,PPP1R13B,ACIN1,CASP2,TNFRSF21,ABR,EIF4G2,FAM82A2,CYCS,TP53INP1,DCTN1,TARDBP,TIAM1,NCSTN,DAPK3,EGLN3,TRIO,NFKBIL1,DIDO1,	1.22E-4
GO:0000087	M phase of mitotic cell cycle	PDS5A,SMC1A,HAUS8,CDC16,LATS2,MAP2K1,BIRC5,MAPRE1,CENPF,NCAPD2,CIT,PBRM1,MAPRE3,DCTN1,TARDBP,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.28E-4
GO:0019941	modification-dependent protein catabolic process	PSMD11,CDC16,PSMD13,PSMD4,YOD1,ARIH2,UBE2Q1,UBE2L3,LRRC41,FOXRED2,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,UBE2J1,TSG101,FBXL5,UBA2,USP21,MYLIP,RNF34,ASB1,ERLIN2,UBR5,HUWE1,DZIP3,UBE2R2,BAP1,CUL2,OTUB1,UBE3B,CDC20,ANAPC7,FEM1C,ANAPC5,CNOT4,MAD2L1,	1.36E-4
GO:0043632	modification-dependent macromolecule catabolic process	PSMD11,CDC16,PSMD13,PSMD4,YOD1,ARIH2,UBE2Q1,UBE2L3,LRRC41,FOXRED2,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,UBE2J1,TSG101,FBXL5,UBA2,USP21,MYLIP,RNF34,ASB1,ERLIN2,UBR5,HUWE1,DZIP3,UBE2R2,BAP1,CUL2,OTUB1,UBE3B,CDC20,ANAPC7,FEM1C,ANAPC5,CNOT4,MAD2L1,	1.36E-4
GO:0016265	death	NUP62,JUN,C3orf38,CLN8,BAG2,E2F1,SCRIB,SH3GLB1,TAX1BP1,BIRC5,PTENP1,BNIP2,ALS2,IGF2,KLF11,PLEKHG4,RYBP,SQSTM1,PRUNE2,BCL2L11,F3,DYRK2,INPP5D,SGMS1,PTEN,PUF60,GARS,ATXN1,RNF34,PPP1R13B,ACIN1,CASP2,TNFRSF21,ABR,EIF4G2,FAM82A2,CYCS,TP53INP1,DCTN1,TARDBP,TIAM1,NCSTN,DAPK3,EGLN3,TRIO,NFKBIL1,DIDO1,	1.41E-4
GO:0051236	establishment of RNA localization	NUP62,NUP188,NPM1,NUPL1,SMG7,NUP160,NUP107,NUP205,SMG6,RGPD5,UPF1,NUP153,DDX39B,	1.47E-4
GO:0050657	nucleic acid transport	NUP62,NUP188,NPM1,NUPL1,SMG7,NUP160,NUP107,NUP205,SMG6,RGPD5,UPF1,NUP153,DDX39B,	1.47E-4
GO:0050658	RNA transport	NUP62,NUP188,NPM1,NUPL1,SMG7,NUP160,NUP107,NUP205,SMG6,RGPD5,UPF1,NUP153,DDX39B,	1.47E-4
GO:0051603	proteolysis involved in cellular protein catabolic process	PSMD11,CDC16,PSMD13,PSMD4,YOD1,ARIH2,UBE2Q1,UBE2L3,LRRC41,FOXRED2,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,UBE2J1,TSG101,FBXL5,UBA2,USP21,MYLIP,RNF34,ASB1,ERLIN2,UBR5,HUWE1,DZIP3,UBE2R2,BAP1,CUL2,OTUB1,UBE3B,CDC20,ANAPC7,FEM1C,ANAPC5,NCSTN,CNOT4,MAD2L1,	1.64E-4
GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	NUP62,NUP188,NPM1,NUPL1,SMG7,NUP160,NUP107,NUP205,RGPD5,SMG6,SLC29A2,UPF1,NUP153,DDX39B,	1.66E-4
GO:0030163	protein catabolic process	PSMD11,CDC16,PSMD13,CLN8,PSMD4,YOD1,ARIH2,UBE2Q1,UBE2L3,LRRC41,FOXRED2,UBE2O,UBR1,SQSTM1,FBXL3,SPOPL,UBE2M,UBE2J1,TSG101,FBXL5,UBA2,USP21,MYLIP,RNF34,ASB1,ERLIN2,UBR5,HUWE1,DZIP3,UBE2R2,BAP1,CUL2,OTUB1,UBE3B,CDC20,ANAPC7,FEM1C,ANAPC5,NCSTN,CNOT4,MAD2L1,	1.68E-4
GO:0048285	organelle fission	PDS5A,SMC1A,HAUS8,CDC16,LATS2,MAP2K1,BIRC5,MAPRE1,CENPF,NCAPD2,CIT,PBRM1,MAPRE3,DCTN1,TARDBP,CDC20,ANAPC7,ANAPC5,MAD2L1,PAPD7,CCNG2,	1.73E-4
GO:0006403	RNA localization	NUP62,NUP188,NPM1,NUPL1,SMG7,NUP160,NUP107,NUP205,SMG6,RGPD5,UPF1,NUP153,DDX39B,	1.98E-4
GO:0033554	cellular response to stress	JUN,SMC1A,MPG,RIF1,CDKN1A,SCAP,ASF1A,GPS1,TLK2,WDR33,RPA2,NFE2L2,DYRK2,CCND1,BMPR2,MAPK9,NONO,MCM7,ATG16L1,MAP3K4,POLE,CRY2,REV3L,RFC3,HSPA5,DHX9,UBR5,ATAD5,FAM129A,NTHL1,MAP3K13,HERPUD1,UPF1,SREBF1,CCDC47,PPP1R15B,PARP1,PAPD7,	2.13E-4
GO:0051028	mRNA transport	RGPD5,NUP62,SMG6,NUP188,UPF1,NUPL1,SMG7,NUP153,NUP107,NUP160,DDX39B,NUP205,	2.28E-4
GO:0045449	regulation of transcription	JUN,MLLT6,EZH2,KLF9,XBP1,EZH1,ZNF417,STAT3,ZNF202,TAF4,UBN1,TRAK1,IGF2,ZMIZ1,SQSTM1,TRIM28,ZNF813,FOXJ3,RPS6KA5,ZBTB41,MYPOP,TULP3,PBRM1,ZFP91,TAF6,ZNFX1,ZNF180,STAT5B,ZBTB33,CBX3,RBBP7,NUP62,ZNF44,NACC2,NCOA4,DNMT3B,MAFG,MAPRE3,ZNF76,VEGFA,CNOT1,RYBP,NFIB,NFE2L2,ZNF295,MCM3,YY1,MCM5,ZNF264,KAT2B,USP21,MCM7,SUV420H1,MED13L,APBB2,SUFU,CENPF,TAF8,PURA,MAP3K13,ZNF384,TARDBP,KDM3B,POLR2A,ZNF143,E2F1,SUPT5H,ZNF148,ZBTB3,MED21,SCAP,USF1,SERTAD2,KLF11,PHF10,MYCBP,RBM15B,TSG101,C5orf41,CERS2,DVL3,NONO,MAP2K1,EIF2C1,ATXN1,RB1,PBXIP1,ZNF703,DDX5,SMAD4,CNOT4,SND1,YWHAQ,SIN3A,EGR2,RUNX3,IKBKAP,SP7,ZNF805,HNRNPUL1,ASF1A,BAZ2A,ZBTB7A,IKZF4,IRF1,IRAK1,RHEBL1,MED12L,RRN3,POGK,PUF60,NPM1,CRY2,ARID4B,HEYL,ZNF217,GLI3,PBX3,MLL2,NR4A1,SREBF1,HDGF,TLE3,	2.96E-4
GO:0042981	regulation of apoptosis	JUN,CLN8,SCRIB,TAX1BP1,PTENP1,BIRC5,IGF2,SQSTM1,PRUNE2,PRKCI,F3,ACTN1,INPP5D,MAPK9,HSPA5,PPP1R13B,ABR,CASP2,ZFP91,TP53INP1,CUL2,HERPUD1,TIAM1,STAT5B,DAPK3,TEX261,TRIO,NFKBIL1,NUP62,RUNX3,SH3GLB1,BNIP2,CDKN1A,PGP,VEGFA,LYST,DNAJC5,BCL2L11,IRAK1,DYRK2,SGMS1,PTEN,EPHA7,NPM1,APBB2,GLI3,CYCS,NR4A1,NCSTN,	4.20E-4
GO:0019220	regulation of phosphate metabolic process	JUN,NUP62,FRS2,CCDC88C,PTENP1,SMG7,CDKN1A,APLP2,ALS2,SMG6,IGF2,GPS1,TGFBR2,IRAK1,CCND1,BMPR2,PTEN,MCM7,NPM1,LATS2,MAP2K1,MAP3K4,ATXN1,DUSP8,PRKACB,RB1,FAM129A,ZFP91,VLDLR,MAP3K13,SMAD4,PARD3,CDC42,SPRED1,	4.88E-4
GO:0051174	regulation of phosphorus metabolic process	JUN,NUP62,FRS2,CCDC88C,PTENP1,SMG7,CDKN1A,APLP2,ALS2,SMG6,IGF2,GPS1,TGFBR2,IRAK1,CCND1,BMPR2,PTEN,MCM7,NPM1,LATS2,MAP2K1,MAP3K4,ATXN1,DUSP8,PRKACB,RB1,FAM129A,ZFP91,VLDLR,MAP3K13,SMAD4,PARD3,CDC42,SPRED1,	4.88E-4
GO:0043067	regulation of programmed cell death	JUN,CLN8,SCRIB,TAX1BP1,PTENP1,BIRC5,IGF2,SQSTM1,PRUNE2,PRKCI,F3,ACTN1,INPP5D,MAPK9,HSPA5,PPP1R13B,ABR,CASP2,ZFP91,TP53INP1,CUL2,HERPUD1,TIAM1,STAT5B,DAPK3,TEX261,TRIO,NFKBIL1,NUP62,RUNX3,SH3GLB1,BNIP2,CDKN1A,PGP,VEGFA,LYST,DNAJC5,BCL2L11,IRAK1,DYRK2,SGMS1,PTEN,EPHA7,NPM1,APBB2,GLI3,CYCS,NR4A1,NCSTN,	5.14E-4
GO:0010604	positive regulation of macromolecule metabolic process	JUN,CDC16,E2F1,STAT3,SUPT5H,ZNF148,SCRIB,MED21,SCAP,USF1,IGF2,SERTAD2,SQSTM1,ZMIZ1,TRIM28,MAPK9,DVL3,MAP2K1,ATXN1,RB1,FAM129A,ZFP91,DDX5,STAT5B,ANAPC7,ANAPC5,SMAD4,PSMD11,NUP62,PSMD13,EGR2,NCOA4,PSMD4,DNMT3B,ASF1A,MAPRE3,VEGFA,IRF1,NFIB,IRAK1,NFE2L2,DYRK2,CCND1,BMPR2,USP21,TAF8,GLI3,NR4A1,CDC20,SREBF1,	5.19E-4
GO:0045786	negative regulation of cell cycle	BTG3,RUNX3,SCRIB,TAF6,LATS2,APBB2,RB1,CENPF,CDKN1A,MAD2L1,PPP1R13B,	5.29E-4
GO:0010941	regulation of cell death	JUN,CLN8,SCRIB,TAX1BP1,PTENP1,BIRC5,IGF2,SQSTM1,PRUNE2,PRKCI,F3,ACTN1,INPP5D,MAPK9,HSPA5,PPP1R13B,ABR,CASP2,ZFP91,TP53INP1,CUL2,HERPUD1,TIAM1,STAT5B,DAPK3,TEX261,TRIO,NFKBIL1,NUP62,RUNX3,SH3GLB1,BNIP2,CDKN1A,PGP,VEGFA,LYST,DNAJC5,BCL2L11,IRAK1,DYRK2,SGMS1,PTEN,EPHA7,NPM1,APBB2,GLI3,CYCS,NR4A1,NCSTN,	5.63E-4
GO:0032269	negative regulation of cellular protein metabolic process	JUN,PSMD11,CDC16,PSMD13,CLN8,EIF2C1,PSMD4,HSP90AB1,FAM129A,DNMT3B,IGF2,EIF2AK1,SET,CDC20,ANAPC7,ANAPC5,MAD2L1,	6.23E-4
GO:0034613	cellular protein localization	JUN,YWHAQ,TOMM20,C16orf70,SH3GLB1,STX16,ARFGAP3,IPO5,MFN2,SNAPIN,SEC23IP,TRAK1,OXA1L,SEC23A,ICMT,EXOC4,PRKCI,TRPC4AP,NPM1,KPNA2,CRY2,SPTBN1,ARCN1,TRAM1,GLI3,NUP205,AP2A2,AP1G1,CDC42,	6.58E-4
GO:0051726	regulation of cell cycle	SMC1A,JUN,CDC16,E2F1,BTG3,RUNX3,SCRIB,BIRC5,PTENP1,CDKN1A,IGF2,CCND1,PTEN,LATS2,NPM1,APBB2,CAV2,RB1,CENPF,PPP1R13B,TAF6,STAT5B,MAD2L1,NFKBIL1,CDC42,CCNG2,	6.68E-4
GO:0016568	chromatin modification	EZH2,EZH1,USP21,SUPT5H,KAT2B,SUV420H1,RPS6KA5,GSG2,UBN1,RB1,PBRM1,DNMT3B,MLL2,ASF1A,HUWE1,BAZ2A,TLK2,NASP,KDM3B,DAPK3,RBBP7,CBX3,	7.02E-4
GO:0070727	cellular macromolecule localization	JUN,YWHAQ,TOMM20,C16orf70,SH3GLB1,STX16,ARFGAP3,IPO5,MFN2,SNAPIN,SEC23IP,TRAK1,OXA1L,SEC23A,ICMT,EXOC4,PRKCI,TRPC4AP,NPM1,KPNA2,CRY2,SPTBN1,ARCN1,TRAM1,GLI3,NUP205,AP2A2,AP1G1,CDC42,	7.33E-4
GO:0051301	cell division	PDS5A,SMC1A,CCND1,HAUS8,CDC16,MCM5,LATS2,BIRC5,MAPRE1,RB1,CENPF,NCAPD2,CIT,MAPRE3,CDC20,ANAPC7,ANAPC5,PARD3,MAD2L1,CDC42,PAPD7,TSG101,CCNG2,	7.60E-4
GO:0043086	negative regulation of catalytic activity	NUP62,PSMD11,CDC16,PSMD13,CLN8,LATS2,BIRC5,DUSP8,PSMD4,RB1,HSPA5,CDKN1A,OXA1L,IGF2,GPS1,NR4A1,HERPUD1,CDC20,ANAPC7,ANAPC5,MAD2L1,SPRED1,	8.05E-4
GO:0032870	cellular response to hormone stimulus	NUP62,PDE3B,STAT3,KAT2B,LATS2,PRKACB,GNB4,USF1,IGF2,VLDLR,GRB2,STAT5B,PRKCI,PARP1,	8.22E-4
GO:0051248	negative regulation of protein metabolic process	JUN,PSMD11,CDC16,PSMD13,CLN8,EIF2C1,PSMD4,HSP90AB1,FAM129A,DNMT3B,IGF2,EIF2AK1,SET,CDC20,ANAPC7,ANAPC5,MAD2L1,	9.42E-4
GO:0006397	mRNA processing	SMC1A,HNRNPM,SRPK1,NONO,PUF60,RBM23,MTPAP,GRSF1,YTHDC1,SF3B2,DHX9,HNRNPUL1,PAPOLA,TARDBP,DDX46,WDR77,DDX5,PRPF8,POLR2A,ADARB1,ADAR,RBM15B,DDX39B,SRSF2,	1.00E-2
GO:0034976	response to endoplasmic reticulum stress	CCND1,HERPUD1,CCDC47,PPP1R15B,NFE2L2,HSPA5,FAM129A,	1.06E-2
GO:0042325	regulation of phosphorylation	JUN,NUP62,FRS2,CCDC88C,PTENP1,CDKN1A,APLP2,ALS2,IGF2,GPS1,TGFBR2,IRAK1,CCND1,BMPR2,PTEN,MCM7,NPM1,LATS2,MAP2K1,MAP3K4,ATXN1,DUSP8,PRKACB,RB1,FAM129A,ZFP91,VLDLR,MAP3K13,SMAD4,PARD3,CDC42,SPRED1,	1.07E-2
GO:0051325	interphase	CCND1,E2F1,CUL2,LATS2,KPNA2,POLE,BIRC5,PRUNE2,ANAPC5,RB1,CENPF,CDKN1A,	1.24E-2
GO:0006984	ER-nuclear signaling pathway	CCND1,HERPUD1,CCDC47,PPP1R15B,NFE2L2,HSPA5,SCAP,	1.25E-2
GO:0001701	in utero embryonic development	PKD2,GNA12,TAF8,TULP3,MED21,MFN2,GLI3,ALS2,MLL2,MAFG,NDEL1,ICMT,ZMIZ1,NASP,BCL2L11,MYO1E,	1.39E-2
GO:0007243	protein kinase cascade	PKD2,FRS2,STAT3,IKBKAP,GNA12,GPS1,IGF2,MARK2,IRAK1,MAPK9,SRPK1,AKAP11,RPS6KA5,LATS2,GSG2,MAP3K4,MAP2K1,DUSP8,PRKACB,WNK1,MAP3K13,GRB2,STAT5B,FYN,DAPK3,SPRED1,	1.40E-2
GO:0006350	transcription	EZH2,KLF9,JUN,XBP1,EZH1,ZNF417,STAT3,ZNF202,TAF4,ZMIZ1,TRIM28,ZNF813,FOXJ3,ZBTB41,MYPOP,PBRM1,ZFP91,PAPOLA,TAF6,ZBTB33,ZNF180,STAT5B,CBX3,DIDO1,RBBP7,ZNF44,NCOA4,MAFG,CNOT1,ZNF76,RYBP,NFIB,TCOF1,NFE2L2,ZNF295,MCM3,YY1,MCM5,ZNF264,SUV420H1,KAT2B,USP21,MCM7,MED13L,TAF8,PURA,ZNF384,TARDBP,KDM3B,POLR2A,E2F1,ZNF143,SUPT5H,ZNF148,ZBTB3,MED21,USF1,SERTAD2,PHF10,KLF11,MYCBP,RBM15B,NONO,EIF2C1,RB1,ZNF703,SMAD4,CNOT4,ADRM1,SND1,SIN3A,EGR2,IKBKAP,RUNX3,SP7,ZNF805,HNRNPUL1,ASF1A,BAZ2A,ZBTB7A,IKZF4,IRF1,MED12L,BMPR2,RRN3,PUF60,CRY2,MTPAP,HEYL,ARID4B,ZNF217,GLI3,MLL2,PBX3,NR4A1,SREBF1,HDGF,TLE3,PARP1,	1.63E-2
GO:0006886	intracellular protein transport	JUN,YWHAQ,TOMM20,C16orf70,STX16,ARFGAP3,IPO5,MFN2,SEC23IP,SNAPIN,TRAK1,SEC23A,ICMT,EXOC4,PRKCI,TRPC4AP,NPM1,KPNA2,CRY2,SPTBN1,ARCN1,TRAM1,GLI3,NUP205,AP2A2,AP1G1,	1.64E-2
GO:0044092	negative regulation of molecular function	NUP62,PKD2,PSMD11,CDC16,PSMD13,CLN8,LATS2,BIRC5,DUSP8,PSMD4,RB1,HSPA5,CDKN1A,OXA1L,IGF2,GPS1,NR4A1,HERPUD1,CDC20,ANAPC7,ANAPC5,IRAK1,MAD2L1,SPRED1,	1.68E-2
GO:0008285	negative regulation of cell proliferation	NUP62,JUN,BTG3,RUNX3,PTENP1,STK11,CDKN1A,CD164,MFN2,KLF11,TGFBR2,NFIB,TSG101,INPP5D,PTEN,KAT2B,NPM1,CAV2,RB1,GLI3,BAP1,CUL2,TAF6,EIF2AK1,SMAD4,NFKBIL1,	2.16E-2
GO:0006511	ubiquitin-dependent protein catabolic process	PSMD11,CDC16,PSMD13,USP21,PSMD4,ERLIN2,ARIH2,UBR5,UBE2L3,BAP1,CUL2,FOXRED2,CDC20,UBR1,ANAPC7,SQSTM1,ANAPC5,MAD2L1,TSG101,	2.29E-2
GO:0010639	negative regulation of organelle organization	NPM1,SET,SPTBN1,MAPRE1,CENPF,MAD2L1,LIMA1,SPTAN1,EPB49,DNMT3B,	2.30E-2
GO:0006915	apoptosis	JUN,C3orf38,BAG2,E2F1,SCRIB,TAX1BP1,SH3GLB1,BIRC5,PTENP1,BNIP2,KLF11,RYBP,SQSTM1,PRUNE2,F3,BCL2L11,DYRK2,INPP5D,SGMS1,PTEN,PUF60,RNF34,PPP1R13B,ACIN1,CASP2,ABR,TNFRSF21,FAM82A2,CYCS,TP53INP1,TIAM1,NCSTN,DAPK3,EGLN3,TRIO,NFKBIL1,DIDO1,	2.46E-2
GO:0010628	positive regulation of gene expression	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,DNMT3B,ASF1A,USF1,MAPRE3,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,MAPK9,DVL3,USP21,ATXN1,RB1,TAF8,GLI3,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	2.55E-2
GO:0007346	regulation of mitotic cell cycle	CCND1,CDC16,BTG3,SCRIB,APBB2,BIRC5,CAV2,RB1,CENPF,IGF2,STAT5B,MAD2L1,NFKBIL1,CDC42,	2.76E-2
GO:0006405	RNA export from nucleus	SMG6,NPM1,UPF1,SMG7,NUP107,NUP160,DDX39B,	2.90E-2
GO:0006260	DNA replication	MCM3,MCM5,MCM7,POLE,REV3L,RFC3,CENPF,PURA,TNKS1BP1,SET,UPF1,NASP,NFIB,RPA2,PAPD7,RBBP7,	2.95E-2
GO:0051252	regulation of RNA metabolic process	EZH2,MLLT6,KLF9,JUN,XBP1,ZNF143,E2F1,ZNF417,STAT3,ZNF202,SUPT5H,ZNF148,TAF4,UBN1,MED21,SCAP,TRAK1,USF1,SERTAD2,IGF2,KLF11,ZMIZ1,SQSTM1,RBM15B,TRIM28,ZNF813,TSG101,C5orf41,CERS2,SRPK1,DVL3,FOXJ3,RPS6KA5,MAP2K1,ATXN1,RB1,DHX9,TULP3,MYPOP,ZNFX1,ZNF180,STAT5B,SMAD4,RBBP7,CBX3,ZNF44,YWHAQ,SIN3A,EGR2,RUNX3,IKBKAP,SP7,NCOA4,ZNF805,DNMT3B,ASF1A,MAFG,MAPRE3,ZNF76,BAZ2A,VEGFA,ZBTB7A,ELAVL1,RYBP,IRF1,NFIB,NFE2L2,MED12L,YY1,POGK,ZNF264,KAT2B,USP21,NPM1,SERBP1,MED13L,HEYL,SUFU,TAF8,MLL2,PBX3,PURA,NR4A1,SREBF1,POLR2A,TLE3,	3.06E-2
GO:0031400	negative regulation of protein modification process	JUN,PSMD11,CDC16,PSMD13,CDC20,SET,ANAPC7,PSMD4,ANAPC5,MAD2L1,FAM129A,DNMT3B,	3.14E-2
GO:0012501	programmed cell death	JUN,C3orf38,BAG2,E2F1,SCRIB,TAX1BP1,SH3GLB1,BIRC5,PTENP1,BNIP2,KLF11,RYBP,SQSTM1,PRUNE2,F3,BCL2L11,DYRK2,INPP5D,SGMS1,PTEN,PUF60,RNF34,PPP1R13B,ACIN1,CASP2,ABR,TNFRSF21,FAM82A2,CYCS,TP53INP1,TIAM1,NCSTN,DAPK3,EGLN3,TRIO,NFKBIL1,DIDO1,	3.15E-2
GO:0051329	interphase of mitotic cell cycle	CCND1,E2F1,CUL2,LATS2,KPNA2,POLE,BIRC5,ANAPC5,RB1,CENPF,CDKN1A,	3.35E-2
GO:0007050	cell cycle arrest	PKD2,EIF4G2,TP53INP1,CUL2,KAT2B,APBB2,RB1,STK11,CDKN1A,MFN2,TSG101,	3.35E-2
GO:0032535	regulation of cellular component size	CAPRIN2,CLN8,NPM1,NUBP1,SPTBN1,APBB2,RB1,VAT1,CDKN1A,SPTAN1,ALS2,ZFP91,SERTAD2,IGF2,DDX5,SMAD4,ARPC2,LIMA1,SGMS1,EPB49,	3.42E-2
GO:0051254	positive regulation of RNA metabolic process	JUN,EGR2,E2F1,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,MAPRE3,USF1,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,TRIM28,DVL3,USP21,MAP2K1,ATXN1,RB1,TAF8,NR4A1,STAT5B,SREBF1,SMAD4,	3.47E-2
GO:0016310	phosphorylation	FRS2,IKBKAP,EPHB4,TESK2,IP6K1,DSTYK,STK11,NIN,TOLLIP,TLK2,FUK,MARK2,TGFBR2,PRKCI,TRIM28,IRAK1,DYRK2,CCND1,BMPR2,MAPK9,NUAK1,ATP5B,SRPK1,RPS6KA5,EPHA7,GSG2,LATS2,MAP2K1,EPHA4,CSNK1G1,SPTBN1,MAP3K4,PRKACB,CAV2,CIT,WNK1,ATP6,MAP3K13,EIF2AK1,FYN,DAPK3,TRIO,PI4KA,UQCRC1,	3.69E-2
GO:0006259	DNA metabolic process	SMC1A,MPG,KLHDC3,DNMT3B,ASF1A,SMG6,BAZ2A,WDR33,SET,NASP,NFIB,RPA2,MCM3,MCM5,NONO,MCM7,KPNA2,CRY2,POLE,REV3L,RFC3,CENPF,PURA,CYCS,TNKS1BP1,NTHL1,TSN,UPF1,PARP1,PAPD7,RBBP7,	3.71E-2
GO:0033043	regulation of organelle organization	CDC16,NPM1,SPTBN1,MAPRE1,CAV2,CENPF,SPTAN1,DNMT3B,IGF2,TLK2,SET,ARPC2,LIMA1,MAD2L1,CDC42,NFKBIL1,EPB49,	4.28E-2
GO:0051168	nuclear export	SMG6,NPM1,UPF1,ATXN1,SMG7,NUP107,NUP160,DDX39B,	4.92E-2
GO:0051640	organelle localization	NDEL1,NIN,NPM1,ARFGAP1,MAP2K1,BIRC5,ARCN1,CENPF,MFN2,CDC42,	5.01E-2
GO:0043065	positive regulation of apoptosis	JUN,RUNX3,SCRIB,SH3GLB1,PTENP1,CDKN1A,LYST,SQSTM1,PRUNE2,BCL2L11,DYRK2,INPP5D,MAPK9,PTEN,EPHA7,APBB2,PPP1R13B,ABR,CASP2,TP53INP1,NR4A1,CUL2,TIAM1,NCSTN,TEX261,DAPK3,TRIO,NFKBIL1,	5.18E-2
GO:0045941	positive regulation of transcription	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DVL3,USP21,ATXN1,RB1,TAF8,GLI3,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	5.39E-2
GO:0006406	mRNA export from nucleus	SMG6,UPF1,SMG7,NUP107,NUP160,DDX39B,	5.55E-2
GO:0008380	RNA splicing	SMC1A,PPAN,HNRNPM,SRPK1,NONO,PUF60,YTHDC1,SF3B2,DHX9,HNRNPUL1,PAPOLA,TARDBP,DDX46,WDR77,DDX5,PRPF8,POLR2A,RBM15B,DDX39B,SRSF2,	5.62E-2
GO:0043068	positive regulation of programmed cell death	JUN,RUNX3,SCRIB,SH3GLB1,PTENP1,CDKN1A,LYST,SQSTM1,PRUNE2,BCL2L11,DYRK2,INPP5D,MAPK9,PTEN,EPHA7,APBB2,PPP1R13B,ABR,CASP2,TP53INP1,NR4A1,CUL2,TIAM1,NCSTN,TEX261,DAPK3,TRIO,NFKBIL1,	5.65E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	JUN,KLF9,SIN3A,ZNF143,E2F1,EGR2,STAT3,SUPT5H,IKBKAP,ZNF202,SP7,ZNF148,TAF4,UBN1,MED21,SCAP,USF1,TRAK1,VEGFA,ZNF76,KLF11,ZBTB7A,ZMIZ1,RYBP,SQSTM1,IRF1,NFIB,TRIM28,MED12L,YY1,MED13L,MAP2K1,ATXN1,RB1,MYPOP,NR4A1,SREBF1,STAT5B,SMAD4,RBBP7,	5.67E-2
GO:0045893	positive regulation of transcription, DNA-dependent	JUN,EGR2,E2F1,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,MAPRE3,USF1,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,TRIM28,DVL3,USP21,ATXN1,RB1,TAF8,NR4A1,STAT5B,SREBF1,SMAD4,	5.70E-2
GO:0007242	intracellular signaling cascade	KLF9,FRS2,STAT3,RAB34,GNB4,IGF2,TLK2,SQSTM1,MARK2,PRKCI,RRAS2,INPP5D,MAPK9,MYO9B,SRPK1,DVL3,RPS6KA5,LATS2,GSG2,MAP3K4,MAP2K1,DUSP8,RB1,ASB1,UBR5,ABR,GRB2,TIAM1,ZBTB33,STAT5B,ARL1,RAB8B,DAPK3,NFKBIL1,SPRED1,NUP62,SMC1A,PKD2,YWHAQ,RAB13,IKBKAP,NCOA4,GNA12,GPS1,TOLLIP,RAB5B,IRAK1,HIST2H4B,DYRK2,RHEBL1,CCND1,RND3,AKAP11,ARHGAP1,APBB2,PRKACB,CIT,WNK1,MAP3K13,FYN,CDC42,PI4KA,	5.87E-2
GO:0010942	positive regulation of cell death	JUN,RUNX3,SCRIB,SH3GLB1,PTENP1,CDKN1A,LYST,SQSTM1,PRUNE2,BCL2L11,DYRK2,INPP5D,MAPK9,PTEN,EPHA7,APBB2,PPP1R13B,ABR,CASP2,TP53INP1,NR4A1,CUL2,TIAM1,NCSTN,TEX261,DAPK3,TRIO,NFKBIL1,	6.00E-2
GO:0031328	positive regulation of cellular biosynthetic process	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,IGF2,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DYRK2,DVL3,USP21,NPM1,ATXN1,RB1,TAF8,HSP90AB1,GLI3,FAM129A,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	6.30E-2
GO:0051338	regulation of transferase activity	NUP62,FRS2,CLN8,PTENP1,CDKN1A,APLP2,ALS2,GPS1,IGF2,TGFBR2,IRAK1,CCND1,PTEN,LATS2,NPM1,MAP3K4,MAP2K1,PRKACB,DUSP8,RB1,VLDLR,MAP3K13,PARD3,SPRED1,CDC42,	6.39E-2
GO:0009890	negative regulation of biosynthetic process	YWHAQ,SIN3A,E2F1,STAT3,ZNF202,SUPT5H,ZNF148,NACC2,SCAP,DNMT3B,IGF2,BAZ2A,KLF11,ZBTB7A,RYBP,RBM15B,TRIM28,TSG101,INPP5D,EIF2C1,ATXN1,ATP1A1,RB1,CENPF,ASB1,MYPOP,GLI3,PURA,PBXIP1,EIF2AK1,SMAD4,RBBP7,CBX3,	6.68E-2
GO:0006468	protein amino acid phosphorylation	FRS2,IKBKAP,EPHB4,TESK2,DSTYK,STK11,NIN,TLK2,MARK2,TGFBR2,PRKCI,TRIM28,IRAK1,DYRK2,BMPR2,CCND1,MAPK9,NUAK1,SRPK1,RPS6KA5,EPHA7,GSG2,LATS2,MAP2K1,CSNK1G1,SPTBN1,MAP3K4,EPHA4,PRKACB,CAV2,CIT,WNK1,MAP3K13,EIF2AK1,FYN,DAPK3,TRIO,	6.87E-2
GO:0010564	regulation of cell cycle process	CDC16,IGF2,NPM1,BIRC5,APBB2,CAV2,RB1,CENPF,MAD2L1,CDC42,NFKBIL1,	6.88E-2
GO:0006793	phosphorus metabolic process	FRS2,PTPN9,EPHB4,PTENP1,TLK2,MARK2,PRKCI,TRIM28,PTPN4,INPP5D,MAPK9,ATP5B,SRPK1,RPS6KA5,GSG2,LATS2,MAP2K1,CSNK1G1,MAP3K4,DUSP8,ATP6,DAPK3,TRIO,UQCRC1,IKBKAP,IP6K1,TESK2,STK11,DSTYK,TOLLIP,NIN,FUK,TGFBR2,IRAK1,DYRK2,CCND1,BMPR2,NUAK1,PTEN,STYX,EPHA7,EPHA4,SPTBN1,PRKACB,CAV2,CIT,WNK1,MAP3K13,EIF2AK1,FYN,PI4KA,	6.92E-2
GO:0006796	phosphate metabolic process	FRS2,PTPN9,EPHB4,PTENP1,TLK2,MARK2,PRKCI,TRIM28,PTPN4,INPP5D,MAPK9,ATP5B,SRPK1,RPS6KA5,GSG2,LATS2,MAP2K1,CSNK1G1,MAP3K4,DUSP8,ATP6,DAPK3,TRIO,UQCRC1,IKBKAP,IP6K1,TESK2,STK11,DSTYK,TOLLIP,NIN,FUK,TGFBR2,IRAK1,DYRK2,CCND1,BMPR2,NUAK1,PTEN,STYX,EPHA7,EPHA4,SPTBN1,PRKACB,CAV2,CIT,WNK1,MAP3K13,EIF2AK1,FYN,PI4KA,	6.92E-2
GO:0045655	regulation of monocyte differentiation	JUN,ACIN1,INPP5D,	7.07E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,IGF2,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DVL3,USP21,MAP2K1,ATXN1,RB1,HSP90AB1,TAF8,GLI3,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	7.11E-2
GO:0007163	establishment or maintenance of cell polarity	SCRIB,CAP1,MARK2,PRKCI,PARD3,CDC42,MAP7,	7.13E-2
GO:0046578	regulation of Ras protein signal transduction	NUP62,RABGAP1,SCRIB,MAP2K1,ARFGAP1,ARFGAP3,MFN2,ALS2,ABR,NDEL1,ICMT,TBC1D20,PLEKHG4,TIAM1,ARHGEF33,TRIO,	7.40E-2
GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,IGF2,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DVL3,USP21,MAP2K1,ATXN1,RB1,TAF8,GLI3,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	7.64E-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	PSMD11,CDC16,PSMD13,CDC20,ANAPC7,PSMD4,ANAPC5,MAD2L1,	7.64E-2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	PSMD11,CDC16,PSMD13,CDC20,ANAPC7,PSMD4,ANAPC5,MAD2L1,	7.64E-2
GO:0043549	regulation of kinase activity	NUP62,CCND1,FRS2,PTEN,NPM1,LATS2,MAP2K1,MAP3K4,PTENP1,DUSP8,PRKACB,RB1,CDKN1A,APLP2,ALS2,IGF2,GPS1,VLDLR,MAP3K13,TGFBR2,PARD3,IRAK1,CDC42,SPRED1,	7.84E-2
GO:0009891	positive regulation of biosynthetic process	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,IGF2,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DYRK2,DVL3,USP21,NPM1,ATXN1,RB1,TAF8,HSP90AB1,GLI3,FAM129A,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	7.86E-2
GO:0006323	DNA packaging	ASF1A,H3F3B,HIST3H2A,NPM1,SET,H1F0,HIST2H4B,NCAPD2,HIST1H3B,ACIN1,HIST2H3A,PAPD7,	8.22E-2
GO:0031327	negative regulation of cellular biosynthetic process	YWHAQ,SIN3A,E2F1,STAT3,ZNF202,SUPT5H,ZNF148,NACC2,DNMT3B,IGF2,BAZ2A,KLF11,ZBTB7A,RYBP,RBM15B,TRIM28,TSG101,INPP5D,EIF2C1,ATXN1,ATP1A1,RB1,CENPF,ASB1,MYPOP,GLI3,PURA,PBXIP1,EIF2AK1,SMAD4,RBBP7,CBX3,	8.67E-2
GO:0051444	negative regulation of ubiquitin-protein ligase activity	PSMD11,CDC16,PSMD13,CDC20,ANAPC7,PSMD4,ANAPC5,MAD2L1,	8.99E-2
GO:0051352	negative regulation of ligase activity	PSMD11,CDC16,PSMD13,CDC20,ANAPC7,PSMD4,ANAPC5,MAD2L1,	8.99E-2
GO:0010557	positive regulation of macromolecule biosynthetic process	NUP62,JUN,E2F1,EGR2,STAT3,SUPT5H,ZNF148,NCOA4,MED21,SCAP,ASF1A,USF1,MAPRE3,IGF2,SERTAD2,VEGFA,ZMIZ1,SQSTM1,IRF1,NFIB,NFE2L2,IRAK1,TRIM28,DYRK2,DVL3,USP21,ATXN1,RB1,TAF8,GLI3,FAM129A,NR4A1,DDX5,SREBF1,STAT5B,SMAD4,	9.04E-2
GO:0006917	induction of apoptosis	MAPK9,PTEN,RUNX3,SH3GLB1,PTENP1,CDKN1A,PPP1R13B,ABR,CASP2,TP53INP1,NR4A1,CUL2,LYST,TIAM1,SQSTM1,PRUNE2,NCSTN,BCL2L11,DAPK3,DYRK2,TRIO,NFKBIL1,	9.48E-2
GO:0007167	enzyme linked receptor protein signaling pathway	JUN,BMPR2,FRS2,PTEN,STAT3,RPS6KA5,EPHB4,EPHA7,SPTBN1,EPHA4,PLEKHA1,PTENP1,IGF2,NIN,VEGFA,GRB2,TIAM1,STAT5B,SMAD4,TGFBR2,IRAK1,TRIO,MYO1E,	9.64E-2
GO:0032869	cellular response to insulin stimulus	USF1,PDE3B,IGF2,VLDLR,GRB2,KAT2B,PRKCI,PARP1,	9.73E-2
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	PSMD11,CDC16,PSMD13,FOXRED2,CDC20,ANAPC7,PSMD4,ANAPC5,ERLIN2,MAD2L1,	9.73E-2
GO:0010498	proteasomal protein catabolic process	PSMD11,CDC16,PSMD13,FOXRED2,CDC20,ANAPC7,PSMD4,ANAPC5,ERLIN2,MAD2L1,	9.73E-2
GO:0012502	induction of programmed cell death	MAPK9,PTEN,RUNX3,SH3GLB1,PTENP1,CDKN1A,PPP1R13B,ABR,CASP2,TP53INP1,NR4A1,CUL2,LYST,TIAM1,SQSTM1,PRUNE2,NCSTN,BCL2L11,DAPK3,DYRK2,TRIO,NFKBIL1,	9.78E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value