ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-26b

MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0004500 hsa-miR-26b-3p	CCUGUUCUCCAUUACUUGGCUC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0000083 hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0004500 hsa-miR-26b-3p	CCUGUUCUCCAUUACUUGGCUC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0000083 hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0000083 hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0004500 hsa-miR-26b-3p	CCUGUUCUCCAUUACUUGGCUC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0000083 hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0004500 hsa-miR-26b-3p	CCUGUUCUCCAUUACUUGGCUC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0000083 hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000084	MIPF0000043	CCGGGACCCAGUUCAAGUAAUUCAGGAUAGGUUGUGUGCUGUCCAGCCUGUUCUCCAUUACUUGGCUCGGGGACCGG	MIMAT0004500 hsa-miR-26b-3p	CCUGUUCUCCAUUACUUGGCUC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

ODAM,PTP4A1,DCAF16,HECA,GRIK2,HEXB,GP1BB,CCNL2,ISOC2,RASIP1,LACTB2,FAM105A,CMTM6,CCNE1,SCO2
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ODAM,PTP4A1,DCAF16,HECA,GRIK2,HEXB,GP1BB,CCNL2,ISOC2,RASIP1,LACTB2,FAM105A,CMTM6,CCNE1,SCO2,GBP2,MEP1A,TIPARP,SRRM2,IFRD2,SLC35F5,SMG6,SIRT4,TBC1D2B,BNC2,EXOC6B,UXT,WDHD1,KCNA5,C5AR1,GRWD1,GINS4,NSL1,EPHA2,LRRC40,ATP7B,CYB561D2,MPV17,REEP3,CAB39L,PRRG3,OAZ1,SMNDC1,C6orf97,HIVEP3,MTCH2,KAT2B,SEC61G,POLG,GALT,STON1-GTF2A1L,RAB23,AIFM1,FOXG1,SLC28A1,RABGGTA,MEGF8,UFSP2,PCYOX1,WDR60,TOX,DGAT1,JAM2,C14orf2,FMO3,GABRG3,LRRC20,IFRD1,MMP10,STAG1,KRTAP5-7,SPATA6,TSGA10,GTPBP4,TRIM6,ATAT1,ITM2A,BCLAF1,MTX1,TGFBI,XK,RAB27A,CH25H,STUB1,SRP9,DEFA1,PDLIM1,RPL28,G3BP2,LSM3,GDF11,C18orf25,ACSF2,SRP14,EP300,ABCB6,C7orf10,INPP5D,APOO,PPM1D,STARD7,TBC1D13,LY6D,DEFB4B,SLC19A2,CSPG5,MAFG,CYP11B2,RNF187,C17orf53,ZNF136,PPAP2A,SNRPC,FBXL6,LMNB1,CDH1,SH3BP1,ADAM18,SETD5,SLC10A3,SSX7,SLC6A14,OBFC2A,S100P,EFHA1,DHRS11,TAX1BP3,KIR3DX1,DHX30,ETV4,ARL5A,PDCL3,CAPN9,CCDC15,TMCC2,HIST2H4A,ZNF480,ZNF556,RAB40B,PFKFB3,CCNDBP1,MEF2D,CRTAM,GTF2A2,HDAC5,MAT2A,ASTN2,CDK19,BOLA2B,CEP85,CHST15,CAMKMT,RNF38,C9orf16,RAB30,SLC26A4,MTCP1NB,IPO13,ZNHIT1,BACE1,SRSF6,PLAG1,GNRHR,RAB36,FOLR2,DHODH,CTSZ,TRIM22,EED,TRIM44,GPR22,TMEM62,UNC13A,FAM20B,CST3,NAA50,DRD3,MYBPC1,ANXA5,KIAA0947,TNP2,ST8SIA2,UBB,CASD1,MED22,RORC,KDM5D,POTEF,AK4,EIF4A1,IL36RN,ANXA1,ALKBH4,OXSR1,NCBP1,MAGT1,MAGIX,PLOD2,TPRKB,NR4A3,VPREB1,AEN,GLRX,LRRC2,ACE2,FCN2,CCNI,CYP24A1,KIAA1462,CACNG3,GLI2,C11orf67,KRT4,CYLC2,LMCD1,SLC16A4,TEX2,SND1,TCEB3B,CASQ1,TRIM65,TET3,RAB8A,ELAVL2,ACAA2,ARHGEF5,ST18,SCARA3,SLC25A23,KLRC2,MTCP1,IL3,ERCC8,ANKRD36BP1,CBX6,DUSP21,ARFRP1,POU4F1,EAF2,FKTN,LUC7L,SESN1,NR2E1,CXADR,GSTT2B,TNS4,KIAA1033,ALG3,TRAM2,FBXO28,FSTL1,ARL4A,HOXA9,ADAM9,C1QTNF9B-AS1,CYTH2,MT1P3,LPHN2,IL13RA2,ADAP2,SLFN12,ITFG1,PAPPA,PSMD7,SMAD7,PFN2,HIST1H2BC,RNASEH1,MED9,ELAVL3,ZBTB38,DAB2,TIMP1,DDX6,DDX25,ICAM5,APBB2,C6orf15,FCGR1B,TMEM74B,RBM3,HOXB1,PTENP1,PITPNC1,OR10H1,BNC1,DCAF8,ARL8B,STRADB,MAP4K3,ARMC8,CDKL2,ANKRD46,CDK5R1,HAUS8,RXRB,FOXD2,FBXO11,SDHB,SERPINI2,MBIP,TMEM168,KCND1,PHLPP2,SLC2A6,COX7A2L,ZDHHC7,ZNF652,VPS54,NR0B2,KIAA0368,SLC39A6,FKBP9L,MPI,ID1,HOXB7,ZNF548,HTRA1,SPINLW1,MGP,TMX4,NTSR1,RRAGC,TM9SF3,MARC2,HSPB7,KIF21B,BAHD1,PRR7,STIL,VAV1,IDI1,FGGY,PTCD3,CTDSP2,IFNG,IER5,POLR2G,AKT1,PPT1,PRDM13,RNF125,COQ2,PAQR4,VIM,DVL3,VANGL2,INSL4,EDN2,PTGS2,PTPRJ,RUVBL1,SALL1,EFNA4,HLA-DQB2,C20orf30,SYNE1,TGFB1I1,RAD51D,GTF2IRD2B,KIAA1324,DYRK3,SLC6A9,CYP4A11,C9orf167,MTERF,BMPR2,KLHL21,TAB3,MCTP2,ERI2,ERCC6L,INPP5B,RBM19,PPP1CC,IL22RA1,PLXNA4,PTPN1,CPB2,TSPAN13,GREM2,ZNF423,POU2F3,SNAPC5,RBMY1HP,WBP5,CES3,DUSP1,TLE4,FBLN5,HMGN5,EIF1AY,GUSB,GPC4,CRIP2,DERA,GGH,PRY,C8orf33,INPP5J,HAGH,USP6,CXCR4,FKBP1B,TFPT,ZSCAN16,USP20,TAF12,FOXE1,TRAPPC6A,SCGB1D2,KIF1B,TLR1,PKIA,IFI16,SLC35D2,SSH1,VANGL1,CCL2,LDLR,HPS4,AP3M2,PSME1,PDGFRL,MUC7,PRR4,CEND1,MYEF2,PARK7,CLIC2,TRPS1,PAK6,RBMY1F,IL12A,TINF2,CCT7,WHAMMP3,ZNF238,SMARCE1,DNAJC11,POFUT2,TMEM156,CSGALNACT2,LIF,ACADS,GDAP1,GPRC5A,FOXF2,WISP3,HSD17B2,SLC35C1,CRLF1,LDB2,DDX60,TMEM206,IRGC,MKNK1,TULP2,HIST1H1D,GDE1,TYMS,CYP2F1,NMD3,RECQL,TFB2M,GSPT2,GABBR1,DLGAP4,MRPL22,PNKP,FAM136A,SLC1A6,TMEM165,SPRR1A,S100A2,FAM193A,NDUFS7,MESDC2,RPN1,SLC7A11,LRRC8D,ARPC5,OXA1L,RPL39,OSTF1,MAST4,CNOT4,CAV2,SLC13A4,FDFT1,TRIM58,RCBTB1,CXCL13,ANAPC13,IFNGR2,PCCA,RAPGEF4,PMP22,TMPRSS6,RAP1B,PEX5L,PDE11A,XRCC5,DERL1,KIF4A,PFDN5,CDH5,TRPC7,GRB7,DYNC2LI1,PIAS2,SFMBT1,CDK18,PER3,IFIH1,TMEM93,SOX5,FHL5,CYTIP,MAGEA9B,YIPF5,TCTN2,GPR107,FANCC,KIAA0232,PLXNA2,IDH2,FTH1,POMP,TAGLN3,COMMD3,BRD8,GSR,ASNS,TRANK1,COL5A1,CMPK1,BCL3,RBM12B,CASP8,ALG9,RNASE1,BRD4,B3GALT1,ACVR1B,CHORDC1,CLSTN1,NLGN4X,KIF1C,CBY1,ATF3,SMYD2,ERC1,MT1P2,ZBTB25,LINC00483,RAD51C,GABRB3,SAFB,G6PD,GPR27,EIF2B1,TRIOBP,ZNF549,TRAF3,FAHD2A,GSTT2,LRRC17,TCN1,SPRY1,CA9,SSH2,TSPAN3,ZNF584,FAM168B,LYZ,CBLL1,PBX3,SECISBP2,OR10H2,OR1A2,GAL3ST1,PHLDA2,SLC34A2,RAB32,LRRC8E,GNB5,FUT8,MAGEC3,IL1R2,SMAD6,MAP1LC3C,TMC7,MED23,ZWINT,GABRE,PSAT1,BRD3,LIN28A,ADAMTS12,FIGF,GRTP1,INHA,GUF1,SUSD5,SUPT3H,ACADSB,GPATCH2,COQ9,OAZ2,ZNF573,MCC,ERAP1,CPM,PIM2,EFNA2,WDR91,FZD5,SRP9P1,OR2W1,PPP1R14B,NUBP2,RORB,UBL3,LETM1,GFOD2,MAGEA9,RARS2,ZNF141,ATP6AP1,MTERFD2,TRIM68,HIST2H2BF,ZNF696,PVALB,SF3B2,F3,DFNA5,CDH9,ZNHIT2,PSMB8,HSF2,SULT1B1,MLNR,CYP2D7P1,UQCRC2,CNNM2,SLAMF1,KIAA0922,LAMP3,TAGLN,C5orf44,DTNB,ZNF195,TMEM2,ACBD3,USP18,YAP1,MLL3,ZFY,ASF1B,BRP44L,PNOC,HSPA1L,LEF1,SMN2,NIP7,FAM114A2,WRAP73,MADD,COASY,TDRD7,GALR3,ZNF468,MB,NR2C2,C11orf16,TM7SF4,GPR63,DCTN3,SV2B,ZCCHC8,ABCG2,KLRC4,TIMM10,C16orf57,SERPINB2,DTL,SIX1,KCNH4,C1orf9,EI24,RAB3A,VPS33A,APOF,NPTN,PIGA,IL20RA,ATP6V0D1,HSD17B14,RPS6KA6,SLC22A13,TRAFD1,CREG1,PPAT,IL17RC,RPL6,SDC3,LIG4,CNTFR,DEFA3,LILRA4,HERPUD1,UBE2E1,ATAD2B,TRAPPC3,S100A7,INSR,C6orf103,FOLH1,RSAD2,TMEM30A,S100A1,NXPH4,DONSON,SNRNP70,DPPA4,AFAP1,MRPL18,CYP4A22,DMXL2,TCF12,BTN3A3,PSTPIP2,KCNF1,SOX3,SEC22A,PDIA5,TBCCD1,DEFB4A,LOC100190938,CXorf38,NDUFB11,DHX35,TNKS,EXT2,KCTD9,CYP4F11,CDC14B,NVL,ITGAX,NTNG1,DNAL4,AUP1,NARS2,MUTED,MVD,ROM1,POU2F1,CADM1,PDHX,CASP4,BATF3,HSF4,PSMC6,STAT6,EVI2A,C17orf39,SRF,MRM1,TOR1B,HSD3B1,TLX3,ABCA1,GJA5,DNAJC2,POM121L1P,RAE1,SOWAHC,RAB3GAP1,ENDOG,COL4A5,MRPS34,FAM190B,ENOX1,MFHAS1,SNAP91,CXCL9,GPR183,FGFR3,TAS2R10,QDPR,KIAA1045,MARCH3,CHST4,CENPQ,KANK2,NDUFS8,DIS3,RBM41,ZNF839,RBMS2,TOP1,RPS6KB2,SLC6A16,CCL7,DNMBP,FAM49B,CRIM1,RPGRIP1,C13orf15,ZNF324B,CHMP3,TMEM187,ARL17A,MNDA,TFEB,CASP7,MFSD9,MTHFS,GADD45A,STARD5,RAP2C,CTSL2,ARRB1,CCDC90A,CXCR1,GNB3,KIAA1644,MREG,MRPS15,KDM4A,C17orf59,SPECC1L,CPA4,ROGDI,SNRPN,BAG3,SNRPD1,GABARAP,KIAA1107,IGFLR1,PMAIP1,DUSP12,PRYP4,NUP153,MANF,ACOX2,USP14,CDK6,ERAP2,TPPP,ZNF672,WLS,GNL3,GPR1,GALNT11,MCL1,NKX2-2,ICMT,CD36,MRPS18B,RCN2,RPA3,STOML2,HSD17B11,DDX3X,KCNQ2,KCTD14,KIAA0101,C14orf133,STXBP3,MRPS28,ZBTB20,ELOVL2,CSN3,IGFBP4,KHK,PFKP,CRYL1,MEF2C,HMGB1,NFKBIE,TRIP6,MRPS2,PCDHB8,CERK,DEC1,TOP2B,POP4,CLINT1,JUN,ALX1,SELENBP1,SH2B3,INPP5K,SIPA1,C1orf216,ASPN,INPP5A,INTS7,CACNB2,ZNF167,CPA1,PRR14,C22orf28,TTI2,NOC3L,RNASET2,OR2S2,POLD4,AGL,MAP3K12,TAS2R13,CARS2,REPIN1,EPHX1,BDNF,CRYZ,MGST3,PLS1,TAF4B,ABCF1,ROS1,MATR3,LCAT,TMCO3,VPS13C,TASP1,LRP1B,PLCH2,SH3GL2,OR10H5,HTT,C13orf27,TUBD1,OFD1,CD97,MDH1,SERPINB1,HEXA,CD28,PIK3CG,RAD54L2,METRN,XDH,ZNF207,ACN9,CCDC109B,FAM208B,GRHL2,ATP6V1A,IVNS1ABP,TMSB15A,ACTR8,PDK4,RGS20,EIF2AK3,SCAND2,IGHMBP2,ANXA8L2,HMOX1,TNFSF9,CCND1,P2RY6,ATP2A2,DUT,ASXL3,CATSPERB,CDKN2D,NAE1,RFX7,C15orf24,SNORA70,SHOC2,C1D,NKX3-2,ANXA8,TGM1,SYNE2,ECT2,GADD45GIP1,N6AMT1,TAZ,HHLA3,RNF6,MMP8,RPLP1,TNFSF15,TAF9,IL1RL1,CLOCK,MRPS16,GNA13,CEMP1,MCM3,TRIM36,ANXA8L1,TMEM208,GALK1,SLC5A3,THAP3,FARP1,MYOG,SLC30A10,BOLA2,NUCB2,PKN1,GSTP1,TIPRL,WRB,TRIB1,FBXO3,TADA3,NPRL2,TMED5,SLC27A6,NDUFB4,FDXR,TCEAL1,TMEM111,NPTXR,FES,HNRNPM,MFSD12,NUDC,FAM98A,FGF9,PODNL1,CCDC41,TK1,TNFAIP3,UGT2A1,SNAI1,TARBP2,EMP3,CA1,UBE2K,NRD1,TENC1,TXK,SF3B3,DCAF10,ZNF862,TRIB3,BTG1,KEAP1,IL7R,SFRP4,STX1A,ARID3B,AGMAT,ZNF551,GPR39,CYBRD1,TRIM17,FAF1,RSRC2,NOP10,UNC93B1,GPBP1L1,POLR2F,WDR83OS,IMPG1,TSFM,IFI44,HECTD3,SI,SLCO1B1,NRN1,EBNA1BP2,NUFIP2,TMEM132A,CDIPT,PDGFB,DUSP14,LBH,FKBP9,LAMA3,PCNA,KCNN2,CNTRL,LMAN2L,XRCC2,TXLNA,POLE3,LGALSL,ZNF85,MCMBP,TRAM1,POTEG,SEC61A2,C3,CHD9,GCNT2,SLC3A2,PBXIP1,SKIV2L2,CXCL6,P2RX2,PLEKHA1,FAM212B,BATF,CELA3B,NT5DC2,VCP,DPYSL3,TSKU,ITGB2,TOM1L2,STK16,RAB11FIP1,PPTC7,LRFN3,RPRD2,CCDC25,C16orf61,GKN1,MED31,FNDC3B,LIG1,RACGAP1,CXCR6,ZBED1,FKRP,GMNN,BMP2,CISH,C12orf5,FBXO24,BCHE,GATA2,MT1M,CST2,WFDC6,PLCB2,PRR5L,GSTA1,PAK1,KRT222,CYTH1,CRADD,TESK1,CARD14,PCBP3,CHMP6,WDR25,SCP2,DSCC1,CRYGC,CCL27,RTF1,KIFC3,SUPT5H,IMP3,BLNK,NSMAF,GRM8,SMN1,PSMC4,KLRC1,CYP27B1,FAM135A,SYNCRIP,SCGB1D1,SHFM1,PRPS2,ARMCX2,DSC1,BRSK2,PANK3,MME,KHDC1,NOX3,DPY19L1,NDUFA5,PARK2,UPF3B,COL4A2,NAA40,FOXM1,AKAP5,CYB5R4,OR2J3,CREBZF,CD248,PPP2R2A,RNF24,FAM198B,CRELD1,DUSP22,CDK14,METTL16,SLC17A6,CAD,MDM2,SRPX,DOCK10,FAHD2B,LHX6,GYS1,RNF2,METTL9,SCN2A,FGF23,SLC22A8,CTH,SNURF,BGLAP,BTG2,C1QTNF1,DCUN1D2,NYX,ZC3H4,FAM127B,ATP1A1,TRAF1,SIX5,UBE2V2,C9orf114,DGKI,C9orf46,CRYAA,SACM1L,SREK1IP1,LTA4H,RRP15,GRB14,SORCS3,THOC7,BLVRB,RIPK4,MAPKAP1,ARFIP2,RMI1,ARHGAP44,SACS,USP3,CYP4F8,GLRX2,TSC22D2,TAC3,ABCD1,GREB1,ANO2,ADRA2A,SNX2,RDBP,IFITM3,GFOD1,TMEM50A,HIPK1,GPNMB,POLR3G,TMEM50B,TPD52L2,BRP44,NAT1,PARP11,C7orf42,DNAJC12,PKD2,ACADM,THAP10,CHMP7,RPS6KC1,UBQLN3,SUN1,DNAJB4,SIDT1,TMEM41B,EIF1AX,GHSR,ICT1,PRICKLE3,RGS3,AOX1,GABRA3,RNF111,BEND4,CDC25B,CHST7,CPN2,DUSP7,SLC38A6,DPF3,PRY2,HSPA12A,CASP9,DNAJC6,SLC25A28,GALNT7,AMDHD2,SLC17A5,S100A7A,ELF4,TP53I3,TAS2R9,SKIL,CBLC,C1orf114,ENTPD7,ZNF81,COL15A1,RYR3,WDR4,NEK9,OR2F2,GREB1L,POLR2H,CCNB1IP1,RRS1,FAM118A,ZMAT4,ANAPC5,COPZ2,CCDC53,PMF1,SMPD3,ITGA3,PPIC,CYR61,MSMO1,MPDZ,TSPAN12,HIST1H2BI,CTSD,LPCAT1,MANSC1,IGSF3,SMS,TERF2,ADARB1,DDB2,FADS2,CYP2D6,ZNF84,MMD,COL4A4,POLA1,KIAA1024,PCDHA6,DCTD,KANSL3,KRTAP5-3,TUSC3,GALR2,NSF,CSNK1G1,QARS,GCH1,PPP3R1,PLCB4,CDK2,KRT18,NRBP1,MAP2K4,USP32P1,PTPRO,RASAL2,RNF144A,GPR17,NME5,URB2,NDUFB5,KIAA1704,ADPGK,EGR3,TPO,SLC25A44,PDGFRA,PNMT,CCDC144A,CLEC2B,CHFR,ADI1,FICD,ACTR5,MATN3,ENOSF1,SERPINH1,PHKA2,LGMN,ABCA6,GPX4,VNN2,LRPAP1,PDK1,POTEJ,PEX11A,RNASE6,SLBP,TCTA,SP4,DCBLD2,HSPA4,ADAM29,MST4,DNAJA3,TRMT2A,PSMD5,MYT1L,MXI1,CA11,BABAM1,CDCA3,ARL4C,AGPAT3,DBNL,IGSF6,RAD54L,LIAS,GGA3,IKBKAP,EEF1A1,LGALS3BP,TEAD3,CCDC28A,GDI1,PIP5K1C,JHDM1D,DCTPP1,MAT2B,CHM,OXCT1,CHST12,IAPP,PMPCA,SLC38A10,FIG4,CNPY3,SPRY2,SMPDL3A,SMC4,PACRG,F13B,PCCB,RASGRF1,ARAP2,TRMT11,NET1,MIA3,CFI,PARP4,C1GALT1C1,C9orf82,PBLD,ECH1,YIF1A,MPDU1,CTNS,HADH,AGT,RCBTB2,SERPINB5,ASNA1,CLTA,HOXC4,NCAPG2,NFE2L2,ATP1A3,JARID2,C9orf95,CASP3,NOP2,PLXNC1,SLC2A4RG,UGDH,ZNF133,ADAMTS1,FKBP2,CACNB4,TSEN34,CHPF,ABCD4,QPRT,CCR6,ANAPC1,VTN,EIF4A3,PARP6,NFKB1,RELB,JOSD1,CNIH4,PCOLCE2,CACNA1S,ARNT2,LSM1,LONP1,ATP6AP2,TRIM13,SAMD14,DPM1,STX12,RABL3,ARMC1,CAV1,MAGEA11,TAF9B,PAF1,GPR135,NCAM2,ZKSCAN3,PQBP1,ATXN2L,PSMC1,FGL2,C11orf30,BCL11B,PCDHA4,BMP8B,TUBGCP4,FN1,RASSF9,UFC1,CIB1,CAMK4,TIA1,CTDNEP1,ZNF140,TLX1,PHGDH,NKX2-5,GPR126,CA2,POU4F3,FAM107B,BUD31,TMPRSS11E,LSAMP,UBE3C,NAGK,DCHS2,ITGB1BP3,IGF2R,PODXL,TSTA3,HIST2H4B,ING2,DIABLO,SEPT7,MNAT1,NAP1L1,MYBBP1A,HGD,ODF2,RAI14,ALPK3,PTRH2,TSHB,YOD1,TRIM6-TRIM34,PDSS2,ZNF23,DNAJA2,IBSP,ZNF35,WASF2,TRPC4,SPC25,PIDD,MPHOSPH8,OTC,PCNT,CHERP,CHCHD8,ABCG4,HSF1,MORC4,PUS7,GTF2IRD2,MEAF6,C1QB,BRDT,PRYP3,FAM3A,KRT32,FRS3,VAMP7,KREMEN2,SRPR,TPM3,OSTM1,ATP5SL,PSMB7,TRPV6,ERBB2IP,TRPM1,NDUFB1,MLXIP,ADM,WARS,PCDHA11,ADNP,C22orf29,NDUFA1,GAS2,IKZF1,CNTLN,KLHL24,TH1L,ANXA3,ANKRD36B,CIAO1,DGKZ,PRSS16,KRT8,ARMC7,LRP4,SRGN,CDK2AP2,CLSTN2,DAK,TMEM30B,TRMT2B,TP53TG5,FBXO5,IL17RB,MDM1,HSD11B1,KDELC1,MARCH1,C1orf63,RRAS2,FKBP14,TNFRSF11A,PAQR6,TXNRD1,GINS1,RXFP3,GDF10,ASPM,PDHA2,MIR22HG,ZFPM2,SPAG1,COLEC12,AGTR1,PDE12,NACC2,ALPI,PCSK1,COX8A,FASLG,GEM

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa04115	p53 signaling pathway	CCND1,CASP9,PPM1D,CASP8,PTENP1,CDK2,SESN1,MDM2,CASP3,TP53I3,PMAIP1,PIDD,CDK6,GADD45A,EI24,DDB2,CCNE1,SERPINB5,	3.94E-4
hsa05222	Small cell lung cancer	CCND1,CASP9,COL4A2,PTGS2,COL4A4,CDK2,PTENP1,RXRB,FN1,AKT1,LAMA3,PIAS2,CDK6,ITGA3,TRAF3,NFKB1,TRAF1,PIK3CG,CCNE1,	1.88E-2
hsa05010	Alzheimer's disease	COX8A,PLCB2,CASP9,CASP8,NAE1,CASP7,NDUFA5,NDUFB1,PLCB4,RYR3,EIF2AK3,ATP2A2,PPP3R1,NDUFS7,SDHB,COX7A2L,MME,CDK5R1,NDUFS8,CACNA1S,CASP3,BACE1,NDUFB4,NDUFB5,NDUFA1,UQCRC2,	2.69E-1
hsa03060	Protein export	SRPR,OXA1L,SRP9P1,SRP9,SRP14,	4.12E-1
hsa03050	Proteasome	IFNG,PSMC6,PSMC4,PSME1,POMP,PSMB7,PSMC1,PSMD7,SHFM1,PSMB8,	4.80E-1

hsa04010	MAPK signaling pathway	JUN,MEF2C,SRF,DUSP14,CACNB2,RELB,CACNB4,FGF9,RPS6KA6,FGF23,CACNG3,PPP3R1,DUSP1,MAP2K4,MKNK1,GADD45A,BDNF,DUSP7,RRAS2,IL1R2,MAP4K3,HSPA1L,PDGFB,RAP1B,PDGFRA,ACVR1B,RASGRF1,PAK1,CACNA1S,AKT1,FGFR3,CASP3,MAP3K12,ARRB1,CDC25B,FASLG,NFKB1,	5.43E-1
hsa00240	Pyrimidine metabolism	POLR2G,POLR2H,POLR2F,TYMS,POLE3,TXNRD1,NME5,DUT,POLD4,CAD,CMPK1,POLA1,POLR3G,DCTD,DHODH,TK1,	6.12E-1
hsa03440	Homologous recombination	RAD54L,XRCC2,RAD51D,RPA3,SHFM1,RAD51C,POLD4,	6.20E-1
hsa03030	DNA replication	MCM3,LIG1,POLA1,POLE3,RPA3,PCNA,RNASEH1,POLD4,	7.14E-1
hsa04070	Phosphatidylinositol signaling system	PLCB2,CDIPT,PLCB4,PTENP1,INPP5J,DGKI,INPP5K,DGKZ,PIP5K1C,INPP5A,INPP5B,PIK3CG,INPP5D,	7.48E-1
hsa00280	Valine, leucine and isoleucine degradation	OXCT1,ACAA2,HADH,PCCB,AOX1,ACADS,ACADSB,PCCA,ACADM,	7.79E-1
hsa00520	Amino sugar and nucleotide sugar metabolism	MPI,UGDH,GALK1,TSTA3,GALT,AMDHD2,HEXB,NAGK,HEXA,	7.79E-1
hsa00790	Folate biosynthesis	QDPR,GGH,GCH1,ALPI,	9.63E-1
hsa00562	Inositol phosphate metabolism	PLCB2,INPP5J,CDIPT,INPP5K,PLCB4,INPP5A,PTENP1,PIP5K1C,INPP5B,PIK3CG,	9.92E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0042127	regulation of cell proliferation	CDH5,JUN,JARID2,CD28,CCL2,DNAJA2,PMP22,ADRA2A,CXADR,ICMT,TPD52L2,ATP6AP1,FOXG1,F3,NKX2-5,PPM1D,HIPK1,EMP3,PTGS2,KRT4,MDM2,HSF4,ARNT2,HSF1,EDN2,CYP27B1,MVD,MXI1,CTH,TIMP1,DRD3,GNL3,STAT6,NOP2,NR2E1,CNTFR,NACC2,TRIB1,GDF11,POLD4,MAFG,TGFB1I1,BCL11B,BDNF,CCND1,BTG1,PDGFB,KAT2B,PDGFRA,TINF2,FOXM1,FIGF,GNRHR,CRIP2,CDC25B,AGT,AGTR1,TNFSF15,BNC1,ROGDI,ADAMTS1,PTENP1,FGF9,WARS,INHA,TLX1,TENC1,INPP5D,BTG2,CIAO1,ANXA1,IL12A,CASP3,FGFR3,SLAMF1,TAX1BP3,SIX5,INSR,MNAT1,ADM,IL3,DUSP22,DNAJA3,CDKN2D,IFNG,TNFRSF11A,BMPR2,ACE2,NAP1L1,DEC1,CDK2,SESN1,CAV2,BMP2,CAV1,GLI2,LIG4,GTPBP4,PPAP2A,CDK6,HMOX1,LIF,ATF3,FTH1,GKN1,GPNMB,	1.47E-4
GO:0033273	response to vitamin	CCND1,PMF1,PTGS2,HSD17B2,CCL2,BGLAP,BMP2,DUSP1,CDKN2D,TSHB,CYP27B1,CYP24A1,SLC10A3,GDAP1,INSR,BCHE,CCNE1,SI,	3.30E-4
GO:0034612	response to tumor necrosis factor	CYP27B1,CASP8,GCH1,ENDOG,INSR,ADAM9,CASP3,	6.72E-4
GO:0044092	negative regulation of molecular function	LRPAP1,GRM8,FICD,OXA1L,ANAPC1,ADRA2A,TRIB3,MBIP,PSMC6,ID1,PSMC4,PSMB7,PSMC1,UBB,AKT1,CASP3,PSMB8,CYP27B1,HERPUD1,ANAPC5,DRD3,INSR,NFKB1,PKD2,DUSP22,PSMD5,TARBP2,DNAJA3,PSMD7,TRIB1,CDKN2D,GALR3,GADD45A,SMAD7,SMAD6,GABBR1,SPRY2,SPRY1,PSME1,CAV1,PKIA,FBXO5,CBLC,GTPBP4,HMOX1,RGS3,FKBP1B,TNKS,UBE2E1,NPRL2,CST3,	7.02E-4
GO:0043086	negative regulation of catalytic activity	GRM8,FICD,DUSP22,PSMD5,TARBP2,PSMD7,TRIB1,DNAJA3,CDKN2D,OXA1L,GALR3,ADRA2A,ANAPC1,GADD45A,SMAD7,SMAD6,TRIB3,MBIP,GABBR1,SPRY2,SPRY1,PSMC6,PSMC4,PSME1,PKIA,CAV1,PSMB7,FBXO5,UBB,PSMC1,AKT1,CBLC,CASP3,PSMB8,CYP27B1,RGS3,FKBP1B,UBE2E1,HERPUD1,NPRL2,ANAPC5,DRD3,NFKB1,CST3,	7.68E-4

GO:0007005	mitochondrion organization	JUN,CASP7,DNAJA3,LONP1,TIMM10,NDUFS7,OXA1L,CXADR,MTX1,TAZ,RNASEH1,TFB2M,RAB3A,CRYAA,POLG,PIM2,NDUFS8,CAV2,MTERF,AKT1,HSPA4,CASP3,PMAIP1,LETM1,MPV17,HTT,	1.08E-2
GO:0032269	negative regulation of cellular protein metabolic process	JUN,SRP9P1,SRP9,RAB23,SRP14,PSMD5,PSMD7,EIF2AK3,ANAPC1,EIF4A3,SMAD7,SMAD6,EIF2B1,PSMC6,PSMC4,PSME1,TINF2,CAV1,PSMB7,PSMC1,UBB,FBXO5,TAF9,PSMB8,GTPBP4,UBE2E1,G6PD,TIA1,ANAPC5,TIMP1,INSR,NFKB1,	1.49E-2
GO:0006694	steroid biosynthetic process	ACBD3,ADM,HSD11B1,HSD17B2,SCP2,HSD3B1,FDXR,HSD17B11,CYP11B2,ACAA2,MSMO1,CYP27B1,FDFT1,G6PD,CH25H,MVD,STARD5,IDI1,	2.22E-2
GO:0042981	regulation of apoptosis	MEF2C,JUN,STRADB,NAE1,GCH1,HMGB1,KRT18,CCL2,PPT1,EIF2AK3,PPP3R1,CRADD,IGF2R,GSTP1,MUTED,F3,NKX2-5,BCL3,ECT2,CADM1,HIPK1,PTGS2,VAV1,AKT1,ARNT2,TAF9,PMAIP1,TP53I3,MST4,TIA1,EI24,CARD14,ENDOG,NFKB1,IFIH1,NR2E1,XRCC2,VCP,NME5,DUSP1,TAF9B,DIABLO,TRAF3,BCLAF1,NET1,BCL11B,BDNF,XRCC5,ADNP,TRAF1,SMAD6,MADD,CDK5R1,BTG1,ACVR1B,APBB2,ADAM9,SERPINB2,MCL1,AGT,SMNDC1,IFI16,FAF1,CDH1,TNFSF15,CASP9,CRTAM,CASP8,PTENP1,INHA,GRIK2,NKX3-2,INPP5D,AEN,PIM2,BTG2,ANXA1,IL12A,CASP4,RASGRF1,ANXA5,UBB,CASP3,ASNS,HERPUD1,TNFAIP3,RAB27A,BAG3,MNAT1,IL3,DNAJA3,POU4F1,CDKN2D,IFNG,CRYAA,LIG4,HMOX1,FASLG,PIK3CG,AIFM1,HTT,	2.32E-2
GO:0010033	response to organic substance	JUN,SRF,CASP8,GCH1,SUPT5H,EPHX1,ACADS,PTENP1,CCL2,EIF2AK3,NR4A3,MGP,TSHB,GGH,LEF1,MB,NKX2-5,HSPA1L,AK4,BTG2,PTGS2,IL12A,ID1,ANXA5,HSPA4,AKT1,HSF1,CASP3,TAF9,ARNT2,HSPB7,PMAIP1,ATP7B,CYP27B1,CYR61,ASNS,HERPUD1,ENDOG,INSR,DRD3,STAT6,RBM3,DNAJB4,SERPINH1,PCSK1,NUDC,GLRX2,ADM,CA2,COLEC12,EP300,VCP,TRIB1,GNB3,DNAJA3,TARBP2,CA9,LIN28A,PPP2R2A,DUSP1,HDAC5,TAF9B,LDLR,IFNG,GPX4,SLC34A2,KHK,NFE2L2,SI,MANF,CCND1,EIF2B1,PDGFB,KAT2B,PDGFRA,CAV2,CAV1,ADAM9,MCL1,GHSR,DERL1,HMOX1,FKBP1B,C1QB,FASLG,PTPN1,MAT2A,TOR1B,BCHE,LCAT,CCNE1,CDH1,	2.33E-2
GO:0034097	response to cytokine stimulus	JUN,SRF,CASP8,GCH1,PDGFRA,PTGS2,DNAJA3,ADAM9,TAF9,CASP3,MCL1,CYP27B1,ENDOG,INSR,STAT6,PCSK1,CCNE1,	2.58E-2
GO:0051248	negative regulation of protein metabolic process	JUN,SRP9P1,SRP9,RAB23,SRP14,PSMD5,PSMD7,EIF2AK3,ANAPC1,EIF4A3,SMAD7,SMAD6,EIF2B1,PSMC6,PSMC4,PSME1,TINF2,CAV1,PSMB7,PSMC1,UBB,FBXO5,TAF9,PSMB8,GTPBP4,UBE2E1,G6PD,TIA1,ANAPC5,TIMP1,INSR,NFKB1,	2.73E-2
GO:0043067	regulation of programmed cell death	MEF2C,JUN,STRADB,NAE1,GCH1,HMGB1,KRT18,CCL2,PPT1,EIF2AK3,PPP3R1,CRADD,IGF2R,GSTP1,MUTED,F3,NKX2-5,BCL3,ECT2,CADM1,HIPK1,PTGS2,VAV1,AKT1,ARNT2,TAF9,PMAIP1,TP53I3,MST4,TIA1,EI24,CARD14,ENDOG,NFKB1,IFIH1,NR2E1,XRCC2,VCP,NME5,DUSP1,TAF9B,DIABLO,TRAF3,BCLAF1,NET1,BCL11B,BDNF,XRCC5,ADNP,TRAF1,SMAD6,MADD,CDK5R1,BTG1,ACVR1B,APBB2,ADAM9,SERPINB2,MCL1,AGT,SMNDC1,IFI16,FAF1,CDH1,TNFSF15,CASP9,CRTAM,CASP8,PTENP1,INHA,GRIK2,NKX3-2,INPP5D,AEN,PIM2,BTG2,ANXA1,IL12A,CASP4,RASGRF1,ANXA5,UBB,CASP3,ASNS,HERPUD1,TNFAIP3,RAB27A,BAG3,MNAT1,IL3,DNAJA3,POU4F1,CDKN2D,IFNG,CRYAA,LIG4,HMOX1,FASLG,PIK3CG,AIFM1,HTT,	3.12E-2
GO:0010035	response to inorganic substance	JUN,GLRX2,MNAT1,CA2,XDH,EP300,PTENP1,CYBRD1,DUSP1,NPTXR,TSHB,MGP,GGH,LEF1,GPX4,FANCC,KHK,MB,ASNA1,CCND1,PDGFRA,S100A7,PTGS2,CAV1,ADAM9,ATP7B,PARK7,HMOX1,INSR,TPO,LCAT,PCSK1,HTT,	3.13E-2
GO:0006260	DNA replication	GINS4,NAE1,HMGB1,POLE3,IGHMBP2,TYMS,DNAJA3,POLD4,CDKN2D,POLA1,RPA3,TK1,PCNA,RNASEH1,DTL,MCM3,POLG,TERF2,PDGFB,TOP1,NAP1L1,GINS1,CDK2,DSCC1,DUT,LIG4,PNKP,RMI1,LIG1,REPIN1,DNAJC2,	3.48E-2
GO:0010941	regulation of cell death	MEF2C,JUN,STRADB,NAE1,GCH1,HMGB1,KRT18,CCL2,PPT1,EIF2AK3,PPP3R1,CRADD,IGF2R,GSTP1,MUTED,F3,NKX2-5,BCL3,ECT2,CADM1,HIPK1,PTGS2,VAV1,AKT1,ARNT2,TAF9,PMAIP1,TP53I3,MST4,TIA1,EI24,CARD14,ENDOG,NFKB1,IFIH1,NR2E1,XRCC2,VCP,NME5,DUSP1,TAF9B,DIABLO,TRAF3,BCLAF1,NET1,BCL11B,BDNF,XRCC5,ADNP,TRAF1,SMAD6,MADD,CDK5R1,BTG1,ACVR1B,APBB2,ADAM9,SERPINB2,MCL1,AGT,SMNDC1,IFI16,FAF1,CDH1,TNFSF15,CASP9,CRTAM,CASP8,PTENP1,INHA,GRIK2,NKX3-2,INPP5D,AEN,PIM2,BTG2,ANXA1,IL12A,CASP4,RASGRF1,ANXA5,UBB,CASP3,ASNS,HERPUD1,TNFAIP3,RAB27A,BAG3,MNAT1,IL3,DNAJA3,POU4F1,CDKN2D,IFNG,CRYAA,LIG4,HMOX1,FASLG,PIK3CG,AIFM1,HTT,	3.49E-2
GO:0055114	oxidation reduction	CYP2F1,TET3,NDUFA5,XDH,PDIA5,ACADS,ACADSB,PDHA2,HGD,TXNRD1,HSD3B1,ACADM,CYP4A11,BLVRB,HSD17B14,HSD17B11,GLRX,FADS2,CYBRD1,NDUFS7,OXA1L,UGDH,SDHB,DHODH,PHGDH,TMX4,CYP2D7P1,CYP2D6,HSD11B1,PTGS2,HSD17B2,MDH1,CRYZ,CYP4F11,CYP11B2,DHRS11,MARC2,ACOX2,FMO3,TP53I3,CYP27B1,MSMO1,CYP24A1,CYP4F8,CYB5R4,TPO,NDUFA1,KDM4A,UQCRC2,NDUFB11,GLRX2,GFOD1,NDUFB1,GSR,AOX1,FDXR,ADI1,PLOD2,HADH,FDFT1,PCYOX1,CH25H,KDM5D,CYP4A22,IDH2,GPX4,TAZ,ENOX1,QDPR,NDUFS8,SCO2,NDUFB4,NDUFB5,HMOX1,G6PD,GFOD2,FTH1,NOX3,TSTA3,CYB561D2,AIFM1,	5.19E-2
GO:0006790	sulfur metabolic process	EXT2,GSTA1,GLRX2,GSR,HAGH,ADI1,CTNS,CHST7,SLC19A2,ICMT,MAT2B,G6PD,CSGALNACT2,GPX4,SMS,PHGDH,MAT2A,CTH,CHST12,CHST4,LIAS,	5.29E-2
GO:0051054	positive regulation of DNA metabolic process	JUN,TERF2,PDGFB,IL3,PDGFRA,TINF2,GLI2,IFNG,TNKS,BABAM1,INSR,STAT6,ERCC8,	5.31E-2
GO:0051384	response to glucocorticoid stimulus	CCND1,ADM,EP300,PTGS2,ACADS,CCL2,CAV1,ADAM9,DUSP1,C1QB,INSR,LCAT,BCHE,CCNE1,PCSK1,SI,	5.76E-2
GO:0051241	negative regulation of multicellular organismal process	LRPAP1,ADM,FGF23,EIF2AK3,ATP2A2,GRIK2,CXADR,IFNG,LGMN,INPP5D,BMPR2,PDGFB,CPB2,PTGS2,ATP1A1,ANXA5,CAV1,IAPP,HSF1,GHSR,TMPRSS6,SRGN,HMOX1,FKBP1B,CST3,NFKB1,BCHE,	5.91E-2
GO:0008219	cell death	POLR2G,MEF2C,JUN,TNFSF15,MEF2D,CASP9,CASP8,NAE1,CASP7,EAF2,PTENP1,KRT18,PPT1,TNFSF9,EIF2AK3,PPP3R1,CRADD,GRIK2,CXCR4,ATP6AP1,F3,TRIB3,INPP5D,ECT2,RRAGC,AEN,CADM1,PIM2,VAV1,CASP4,RASGRF1,UBB,AKT1,CASP3,KRT8,PMAIP1,SRGN,PIDD,C1D,TNS4,MST4,ITGB2,TIA1,TNFAIP3,ENDOG,NFKB1,SMN2,SMN1,GAS2,BAG3,GLRX2,PTRH2,EP300,MMD,DUSP22,IGHMBP2,VCP,POU4F3,DNAJA3,L1CAM,CDKN2D,TAF9B,IFNG,DIABLO,TRAF3,NET1,GADD45A,TRAF1,CTSD,PARP4,MADD,PDCL3,CIB1,TOP1,PAK1,FIG4,IAPP,SYNE1,MCL1,LIG4,SCN2A,HMOX1,SMNDC1,FASLG,TSTA3,PHLDA2,FAF1,AIFM1,HTT,LYZ,	6.41E-2
GO:0043066	negative regulation of apoptosis	MEF2C,STRADB,HMGB1,PTENP1,KRT18,CCL2,PPT1,GRIK2,GSTP1,MUTED,F3,NKX2-5,NKX3-2,BCL3,PIM2,BTG2,ANXA1,ANXA5,UBB,AKT1,ARNT2,TAF9,CASP3,ASNS,TNFAIP3,NFKB1,MNAT1,NR2E1,BAG3,IL3,XRCC2,NME5,DNAJA3,TAF9B,CDKN2D,BCL11B,BDNF,XRCC5,ADNP,SMAD6,CRYAA,APBB2,SERPINB2,LIG4,MCL1,HMOX1,AGT,PIK3CG,HTT,	6.63E-2
GO:0051259	protein oligomerization	TRIM6-TRIM34,TRIM22,SEPT7,KCNA5,CASP8,GCH1,COLEC12,NACC2,IGHMBP2,VCP,TRIM6,LONP1,EIF2AK3,OTC,C1QTNF1,SKIL,CRYAA,STXBP3,CAV2,ANXA5,CAV1,HSF4,DCTPP1,PDSS2,QPRT,CTH,INSR,PFKP,CDH1,	6.82E-2
GO:0045862	positive regulation of proteolysis	IFNG,EP300,STUB1,MDM2,ADAM9,NRD1,AKT1,SMAD7,	6.92E-2
GO:0006575	cellular amino acid derivative metabolic process	GLRX2,GSTA1,GSR,GCH1,HAGH,ACADM,CTNS,SULT1B1,PCYOX1,ICMT,OAZ2,GPX4,OAZ1,SMS,PHGDH,VNN2,PARK2,AGMAT,PNMT,MAT2B,G6PD,MAT2A,CTH,DRD3,BCHE,LCAT,HTT,	6.94E-2
GO:0032270	positive regulation of cellular protein metabolic process	IL3,EP300,CD28,STUB1,PSMD5,PSMD7,DNAJA3,NRD1,IFNG,ANAPC1,SMAD7,BCL3,CCND1,BMPR2,IL12A,PSMC6,PSMC4,MDM2,PSME1,BMP2,CAV1,PSMB7,ADAM9,PSMC1,UBB,FBXO5,AKT1,PSMB8,LIF,UBE2E1,AGT,AGTR1,CARD14,ANAPC5,INSR,	6.96E-2
GO:0012501	programmed cell death	POLR2G,MEF2C,JUN,TNFSF15,MEF2D,CASP9,CASP8,NAE1,CASP7,EAF2,PTENP1,KRT18,PPT1,TNFSF9,EIF2AK3,PPP3R1,CRADD,GRIK2,CXCR4,F3,TRIB3,INPP5D,ECT2,RRAGC,AEN,CADM1,PIM2,VAV1,CASP4,RASGRF1,UBB,AKT1,CASP3,KRT8,PMAIP1,SRGN,PIDD,C1D,TNS4,MST4,ITGB2,TIA1,TNFAIP3,ENDOG,NFKB1,GAS2,BAG3,GLRX2,PTRH2,EP300,DUSP22,VCP,POU4F3,DNAJA3,CDKN2D,TAF9B,IFNG,DIABLO,TRAF3,NET1,GADD45A,TRAF1,MADD,PDCL3,CIB1,TOP1,PAK1,IAPP,MCL1,LIG4,SCN2A,SMNDC1,FASLG,PHLDA2,FAF1,AIFM1,HTT,	7.47E-2
GO:0048534	hemopoietic or lymphoid organ development	IKZF1,CASP8,HOXB7,RELB,CACNB4,JARID2,VPS33A,ROGDI,CD28,DNAJA3,INHA,HDAC5,CXCL13,TLX1,TNFRSF11A,BCL11B,XRCC5,TAZ,MB,DYRK3,NKX3-2,NKX2-5,SIX1,SH2B3,IL7R,BCL3,BLNK,HOXA9,TIPARP,LIG4,GPR183,CRIP2,CDK6,G6PD,OSTM1,TIMP1,IFI16,TM7SF4,	7.55E-2
GO:0048545	response to steroid hormone stimulus	ADM,CA2,EP300,ACADS,PTENP1,CCL2,CA9,DUSP1,LDLR,TSHB,GPX4,SLC34A2,NKX2-5,SI,CCND1,PDGFB,PDGFRA,PTGS2,CAV2,CAV1,ADAM9,ARNT2,CYP27B1,HMOX1,C1QB,INSR,BCHE,LCAT,CCNE1,PCSK1,	7.56E-2
GO:0016265	death	POLR2G,MEF2C,JUN,TNFSF15,MEF2D,CASP9,CASP8,NAE1,CASP7,EAF2,PTENP1,KRT18,PPT1,TNFSF9,EIF2AK3,PPP3R1,CRADD,GRIK2,CXCR4,ATP6AP1,F3,TRIB3,INPP5D,ECT2,RRAGC,AEN,CADM1,PIM2,VAV1,CASP4,RASGRF1,UBB,AKT1,CASP3,KRT8,PMAIP1,SRGN,PIDD,C1D,TNS4,MST4,ITGB2,TIA1,TNFAIP3,ENDOG,NFKB1,SMN2,SMN1,GAS2,BAG3,GLRX2,PTRH2,EP300,MMD,DUSP22,IGHMBP2,VCP,POU4F3,DNAJA3,L1CAM,CDKN2D,TAF9B,IFNG,DIABLO,TRAF3,NET1,GADD45A,TRAF1,CTSD,PARP4,MADD,PDCL3,CIB1,TOP1,PAK1,FIG4,IAPP,SYNE1,MCL1,LIG4,SCN2A,HMOX1,SMNDC1,FASLG,TSTA3,PHLDA2,FAF1,AIFM1,HTT,LYZ,	7.69E-2
GO:0031400	negative regulation of protein modification process	JUN,PSMC6,PSMC4,PSME1,PSMD5,TINF2,CAV1,UBB,PSMB7,PSMD7,FBXO5,PSMC1,PSMB8,GTPBP4,ANAPC1,UBE2E1,G6PD,ANAPC5,INSR,SMAD7,SMAD6,	7.78E-2
GO:0051051	negative regulation of transport	CRYAA,PKD2,KCNA5,G3BP2,STXBP3,PTGS2,PTENP1,PKIA,FGF23,AKT1,INHA,EDN2,GHSR,SRGN,HMOX1,SIRT4,LIF,MXI1,INSR,DRD3,NFKB1,FAF1,NFKBIE,	7.83E-2
GO:0033554	cellular response to stress	JUN,STRADB,CASP9,NAE1,HMGB1,RAD51D,TYMS,EIF2AK3,MAP2K4,DGKZ,RPA3,PKN1,RAD51C,BCL3,HSPA1L,AEN,MAP4K3,MBIP,HIPK1,BTG2,SHFM1,DBNL,MAP3K12,CASP3,PNKP,ASNS,HERPUD1,TPO,RAD54L,GLRX2,MNAT1,ADM,C11orf30,XRCC2,IGHMBP2,VCP,TRIB1,LONP1,POLD4,CDKN2D,IFNG,BABAM1,GADD45A,UBE2V2,RECQL,GPX4,POLA1,XRCC5,DDB2,FANCC,PCNA,CTSD,NFE2L2,DTL,PARP4,CCND1,BMPR2,POLG,TERF2,EIF2B1,CIB1,SESN1,CAV1,LIG4,DERL1,HMOX1,G6PD,LIG1,IFI16,ERCC8,AIFM1,OBFC2A,	7.84E-2
GO:0001990	regulation of systemic arterial blood pressure by hormone	ACE2,AGT,AGTR1,ATP6AP2,DRD3,CYP11B2,EDN2,	8.52E-2
GO:0043069	negative regulation of programmed cell death	MEF2C,STRADB,HMGB1,PTENP1,KRT18,CCL2,PPT1,GRIK2,GSTP1,MUTED,F3,NKX2-5,NKX3-2,BCL3,PIM2,BTG2,ANXA1,ANXA5,UBB,AKT1,ARNT2,TAF9,CASP3,ASNS,TNFAIP3,NFKB1,MNAT1,NR2E1,BAG3,IL3,XRCC2,NME5,DNAJA3,TAF9B,CDKN2D,BCL11B,BDNF,XRCC5,ADNP,SMAD6,CRYAA,APBB2,SERPINB2,LIG4,MCL1,HMOX1,AGT,PIK3CG,HTT,	8.56E-2
GO:0009628	response to abiotic stimulus	JUN,CASP9,CASP7,CCL2,MGP,PKN1,BCL3,AEN,HSPA1L,MBIP,PPM1D,BTG2,IL12A,ATP1A3,HSPA4,AKT1,HSPB7,CASP3,HSF1,ARRB1,PNKP,DRD3,SCARA3,RBM3,DNAJB4,RAD54L,PKD2,GLRX2,ADM,CA2,XRCC2,STX1A,CLOCK,DUSP1,CDKN2D,BABAM1,DDB2,RAB3A,CRYAA,CCND1,EIF2B1,CAV1,BMP2,LIG4,AGT,NOX3,MAT2A,ERCC8,OBFC2A,HTT,	8.61E-2
GO:0031397	negative regulation of protein ubiquitination	PSMC6,PSMC4,PSME1,PSMD5,UBB,PSMD7,FBXO5,PSMC1,PSMB7,PSMB8,GTPBP4,ANAPC1,UBE2E1,ANAPC5,SMAD7,	8.69E-2
GO:0051353	positive regulation of oxidoreductase activity	CYP27B1,IFNG,GCH1,AGT,AGTR1,FGF23,AKT1,EDN2,	8.71E-2
GO:0001558	regulation of cell growth	DAB2,EP300,N6AMT1,PPT1,CDKN2D,TAF9B,NET1,IL17RB,WISP3,RNF6,HTRA1,CISH,SIPA1,BTG1,ACVR1B,APBB2,FOXM1,IGFBP4,CRIM1,AKT1,TAF9,DCBLD2,CYP27B1,CYR61,TP53TG5,AGT,AGTR1,EI24,CTH,DNAJC2,	8.71E-2
GO:0060548	negative regulation of cell death	MEF2C,STRADB,HMGB1,PTENP1,KRT18,CCL2,PPT1,GRIK2,GSTP1,MUTED,F3,NKX2-5,NKX3-2,BCL3,PIM2,BTG2,ANXA1,ANXA5,UBB,AKT1,ARNT2,TAF9,CASP3,ASNS,TNFAIP3,NFKB1,MNAT1,NR2E1,BAG3,IL3,XRCC2,NME5,DNAJA3,TAF9B,CDKN2D,BCL11B,BDNF,XRCC5,ADNP,SMAD6,CRYAA,APBB2,SERPINB2,LIG4,MCL1,HMOX1,AGT,PIK3CG,HTT,	9.02E-2
GO:0051444	negative regulation of ubiquitin-protein ligase activity	PSMC6,PSMC4,PSMD5,PSME1,UBB,PSMD7,FBXO5,PSMC1,PSMB7,PSMB8,ANAPC1,UBE2E1,ANAPC5,SMAD7,	9.08E-2
GO:0051352	negative regulation of ligase activity	PSMC6,PSMC4,PSMD5,PSME1,UBB,PSMD7,FBXO5,PSMC1,PSMB7,PSMB8,ANAPC1,UBE2E1,ANAPC5,SMAD7,	9.08E-2
GO:0043627	response to estrogen stimulus	CCND1,PDGFB,PDGFRA,CA2,PTGS2,PTENP1,CAV2,CAV1,ARNT2,DUSP1,TSHB,CYP27B1,LDLR,HMOX1,GPX4,INSR,SLC34A2,CCNE1,NKX2-5,	9.16E-2
GO:0008285	negative regulation of cell proliferation	JUN,CDH5,TNFSF15,JARID2,ADAMTS1,PTENP1,WARS,PMP22,CXADR,TENC1,INPP5D,PPM1D,BTG2,EMP3,IL12A,PTGS2,KRT4,CASP3,HSF1,TAX1BP3,CYP27B1,SIX5,MXI1,CTH,ADM,DNAJA3,TRIB1,GDF11,CDKN2D,TGFB1I1,IFNG,BCL11B,BDNF,BTG1,KAT2B,DEC1,SESN1,TINF2,CAV2,CAV1,GNRHR,BMP2,PPAP2A,GTPBP4,HMOX1,CDK6,AGT,FTH1,GPNMB,	9.51E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value