ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-23b

MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0004587 hsa-miR-23b-5p	UGGGUUCCUGGCAUGCUGAUUU	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .
MI0000439	MIPF0000027	CUCAGGUGCUCUGGCUGCUUGGGUUCCUGGCAUGCUGAUUUGUGACUUAAGAUUAAAAUCACAUUGCCAGGGAUUACCACGCAACCACGACCUUGGC	MIMAT0000418 hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	This miRNA sequence is predicted based on homology to a verified miRNAfrom mouse , later verified in human .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

AARS2,WDR54,AP4B1,RPS27A,MPV17,NMT1,CDC73,TSR1,CEPT1,EP300,SNRPC,XPO1,EIF4B,EIF4A1,NSD1
more » AARS2,WDR54,AP4B1,RPS27A,MPV17,NMT1,CDC73,TSR1,CEPT1,EP300,SNRPC,XPO1,EIF4B,EIF4A1,NSD1,SORCS2,ZMYM2,FLNA,ITFG1,USP31,PRR14L,BBS12,CCNB2,CPSF7,GANAB,AKT1,HIF1AN,TAB3,CDCA8,UNC45A,PCMTD2,CUL4A,PPM1A,CCT7,EWSR1,SUPT7L,CEP104,PRODH,TCF25,RAF1,BLOC1S2,WWP2,SOS1,DGCR2,CYB561D1,UQCRC2,LASP1,AKAP11,CAP1,RBPMS2,SBF1,STK11IP,COX1,DNMBP,STAT5B,DDX27,ILVBL,CLUAP1,SLC9A6,TPCN1,PSAP,HK1,PPARGC1B,DHX33,ATG12,RAB5B,ILF2,ATP5A1,CD302,GHITM,CDC20,ATP1A1,RPL22,NHP2L1,ANKRD17,PI4KB,PHF10,AMOTL1,CHUK,PLAU,BCL7B,DHX57,JAK1,C11orf68,SLC6A15,PRDX1,ECH1,GNA12,PLOD1,ACTN4,PANK2,CPSF3L,RPN2,MET,HNRNPUL1,TAB2,DIAPH1,NPM1,GTF2I,G3BP1,CCDC88C,MLLT6,PSMD14,GAPDH,PRAP1,E2F4,RRAGD,RMND5A,LBR,HERC3,C8orf33,E2F1,HNRNPK,PDCD6IP,MAP4,DNAJC5,SPEN,UBR3,BCL2L1,SOCS6,ITPR3,FAM168B,RPL19,MSH6,COPA,KIAA1267,ZEB1,VHL,PTK2B,SLC16A1,DONSON,KIAA1279,MED4,GJA1,ATF7IP,SYDE2,SPTY2D1,ACAT1,ARFIP1,ALDOA,SSRP1,GNS,ZIC5,IMPDH2,ABCF1,RAD51,CATSPERB,TNRC6B,GNB2L1,DDX47,ABCC4,RB1,ABCC1,BCS1L,ZNFX1,KDM1A,CSDE1,CMTM4,CPEB3,INPP4A,MCFD2,CDK2,CRKL,ATXN10,EPB49,PNN,TCP1,PPP1CB,SRC,EEF1A1,PTEN,NOTCH1,CLTA,KIAA0090,MED13L,PRPF6,HIST2H4B,HNRNPL

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05220	Chronic myeloid leukemia	CRKL,E2F1,CHUK,BCL2L1,RAF1,STAT5B,RB1,AKT1,SOS1,	1.29E-5
hsa05200	Pathways in cancer	PTEN,E2F1,CHUK,RAF1,BCL2L1,EP300,CDK2,VHL,RB1,JAK1,AKT1,CRKL,STAT5B,RAD51,MSH6,MET,SOS1,	1.92E-5
hsa05215	Prostate cancer	PTEN,E2F1,CHUK,RAF1,EP300,CDK2,RB1,AKT1,SOS1,	4.57E-5
hsa05212	Pancreatic cancer	E2F1,CHUK,BCL2L1,RAF1,RAD51,RB1,JAK1,AKT1,	8.52E-5
hsa05211	Renal cell carcinoma	CRKL,RAF1,EP300,VHL,MET,AKT1,SOS1,	5.60E-4

hsa04510	Focal adhesion	SRC,PTEN,CRKL,DIAPH1,RAF1,PPP1CB,FLNA,ACTN4,MET,AKT1,SOS1,	7.26E-4
hsa05222	Small cell lung cancer	PTEN,E2F1,CHUK,BCL2L1,CDK2,RB1,AKT1,	1.47E-2
hsa05214	Glioma	PTEN,E2F1,RAF1,RB1,AKT1,SOS1,	2.33E-2
hsa05218	Melanoma	PTEN,E2F1,RAF1,RB1,MET,AKT1,	3.94E-2
hsa05223	Non-small cell lung cancer	E2F1,RAF1,RB1,AKT1,SOS1,	8.28E-2
hsa04012	ErbB signaling pathway	SRC,CRKL,RAF1,STAT5B,AKT1,SOS1,	9.30E-2
hsa04110	Cell cycle	E2F1,CCNB2,EP300,CDC20,CDK2,RB1,E2F4,	1.05E-1
hsa05221	Acute myeloid leukemia	CHUK,RAF1,STAT5B,AKT1,SOS1,	1.06E-1
hsa05210	Colorectal cancer	RAF1,MSH6,MET,AKT1,SOS1,	3.61E-1
hsa04914	Progesterone-mediated oocyte maturation	CCNB2,RAF1,PPP1CB,CDK2,AKT1,	3.89E-1
hsa05213	Endometrial cancer	PTEN,RAF1,AKT1,SOS1,	4.20E-1
hsa04540	Gap junction	GJA1,SRC,RAF1,ITPR3,SOS1,	4.33E-1
hsa04010	MAPK signaling pathway	PPM1A,CRKL,CHUK,RAF1,TAB2,FLNA,GNA12,AKT1,SOS1,	4.45E-1
hsa04910	Insulin signaling pathway	HK1,CRKL,RAF1,PPP1CB,AKT1,SOS1,	5.04E-1
hsa04912	GnRH signaling pathway	SRC,RAF1,ITPR3,PTK2B,SOS1,	5.80E-1
hsa04062	Chemokine signaling pathway	CRKL,CHUK,RAF1,STAT5B,PTK2B,AKT1,SOS1,	5.96E-1
hsa04720	Long-term potentiation	RAF1,ITPR3,EP300,PPP1CB,	8.06E-1
hsa04630	Jak-STAT signaling pathway	BCL2L1,EP300,STAT5B,JAK1,AKT1,SOS1,	8.10E-1
hsa04114	Oocyte meiosis	CCNB2,ITPR3,PPP1CB,CDC20,CDK2,	8.13E-1
hsa04070	Phosphatidylinositol signaling system	PTEN,ITPR3,PI4KB,INPP4A,	9.80E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0065003	macromolecular complex assembly	SRC,CCDC88C,XPO1,NPM1,ITPR3,FLNA,VHL,TCP1,TSR1,PRPF6,GJA1,DIAPH1,MED4,RAD51,PTK2B,SNRPC,HIST2H4B,GTF2I,BCS1L,	2.45E-4
GO:0010604	positive regulation of macromolecule metabolic process	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,PSMD14,BLOC1S2,RB1,AKT1,PRPF6,RPS27A,PPARGC1B,GJA1,PPM1A,CDC20,STAT5B,RAD51,PTK2B,NSD1,ZEB1,	2.84E-4
GO:0031328	positive regulation of cellular biosynthetic process	E2F1,ILF2,EP300,NPM1,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,AKT1,PRPF6,RPS27A,PPARGC1B,PPM1A,STAT5B,PTK2B,NSD1,ZEB1,	3.51E-4
GO:0009891	positive regulation of biosynthetic process	E2F1,ILF2,EP300,NPM1,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,AKT1,PRPF6,RPS27A,PPARGC1B,PPM1A,STAT5B,PTK2B,NSD1,ZEB1,	4.17E-4
GO:0051173	positive regulation of nitrogen compound metabolic process	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,AKT1,PRPF6,RPS27A,PPARGC1B,PPM1A,STAT5B,RAD51,NSD1,ZEB1,	4.91E-4

GO:0043933	macromolecular complex subunit organization	SRC,CCDC88C,XPO1,NPM1,ITPR3,FLNA,VHL,TCP1,TSR1,PRPF6,GJA1,DIAPH1,MED4,RAD51,PTK2B,SNRPC,HIST2H4B,GTF2I,BCS1L,	5.37E-4
GO:0001666	response to hypoxia	BCL2L1,EP300,STAT5B,VHL,PTK2B,ACTN4,PLOD1,PLAU,	5.70E-4
GO:0010557	positive regulation of macromolecule biosynthetic process	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,AKT1,PRPF6,RPS27A,PPARGC1B,PPM1A,STAT5B,PTK2B,NSD1,ZEB1,	5.84E-4
GO:0034622	cellular macromolecular complex assembly	SRC,DIAPH1,XPO1,NPM1,FLNA,PTK2B,SNRPC,TCP1,TSR1,HIST2H4B,BCS1L,PRPF6,	5.92E-4
GO:0070482	response to oxygen levels	BCL2L1,EP300,STAT5B,VHL,PTK2B,ACTN4,PLOD1,PLAU,	7.74E-4
GO:0051329	interphase of mitotic cell cycle	E2F1,PPP1CB,CUL4A,CDK2,RB1,E2F4,AKT1,	8.03E-4
GO:0051325	interphase	E2F1,PPP1CB,CUL4A,CDK2,RB1,E2F4,AKT1,	9.33E-4
GO:0006461	protein complex assembly	SRC,CCDC88C,XPO1,NPM1,ITPR3,FLNA,VHL,TCP1,GJA1,DIAPH1,MED4,RAD51,PTK2B,GTF2I,BCS1L,	9.85E-4
GO:0070271	protein complex biogenesis	SRC,CCDC88C,XPO1,NPM1,ITPR3,FLNA,VHL,TCP1,GJA1,DIAPH1,MED4,RAD51,PTK2B,GTF2I,BCS1L,	9.85E-4
GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,PRPF6,RPS27A,PPARGC1B,PPM1A,STAT5B,RAD51,NSD1,ZEB1,	9.85E-4
GO:0045941	positive regulation of transcription	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,RPS27A,PRPF6,PPARGC1B,PPM1A,STAT5B,NSD1,ZEB1,	9.88E-4
GO:0007015	actin filament organization	DIAPH1,ALDOA,FLNA,PTK2B,ACTN4,EPB49,	1.00E-2
GO:0010628	positive regulation of gene expression	E2F1,ILF2,EP300,ATF7IP,NOTCH1,CDK2,VHL,BLOC1S2,RB1,RPS27A,PRPF6,PPARGC1B,PPM1A,STAT5B,NSD1,ZEB1,	1.33E-2
GO:0034621	cellular macromolecular complex subunit organization	SRC,DIAPH1,XPO1,NPM1,FLNA,PTK2B,SNRPC,TCP1,TSR1,HIST2H4B,BCS1L,PRPF6,	1.51E-2
GO:0000278	mitotic cell cycle	CDCA8,E2F1,CCNB2,PPP1CB,CDC20,CUL4A,CDK2,PSMD14,RB1,E2F4,AKT1,RPS27A,	2.01E-2
GO:0010605	negative regulation of macromolecule metabolic process	WWP2,E2F1,BCL2L1,NPM1,ATF7IP,FLNA,PSMD14,VHL,TCF25,RB1,RPS27A,SPEN,CDC20,KDM1A,MSH6,NSD1,ZEB1,TNRC6B,	2.05E-2
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	SRC,PTEN,RAF1,STAT5B,FLNA,PTK2B,MET,AKT1,SOS1,	2.73E-2
GO:0022402	cell cycle process	CDCA8,E2F1,NPM1,CDK2,PSMD14,RB1,E2F4,AKT1,RPS27A,CCNB2,CUL4A,CDC20,PPP1CB,RAD51,MSH6,	2.80E-2
GO:0000082	G1/S transition of mitotic cell cycle	PPP1CB,CUL4A,RB1,E2F4,AKT1,	2.94E-2
GO:0048011	nerve growth factor receptor signaling pathway	SRC,RAF1,SOS1,	3.02E-2
GO:0007049	cell cycle	CDCA8,E2F1,EP300,NPM1,CDC73,CDK2,PSMD14,RB1,E2F4,AKT1,RPS27A,PDCD6IP,CCNB2,PPP1CB,CUL4A,CDC20,RAD51,MSH6,	3.64E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	E2F1,EP300,ATF7IP,NOTCH1,MED13L,VHL,TCF25,RB1,E2F4,PRPF6,PPARGC1B,SPEN,MED4,STAT5B,KDM1A,NSD1,ZEB1,	4.57E-2
GO:0022403	cell cycle phase	CDCA8,E2F1,CCNB2,PPP1CB,CDC20,CUL4A,CDK2,RAD51,MSH6,RB1,E2F4,AKT1,	4.73E-2
GO:0007265	Ras protein signal transduction	SRC,CRKL,RAF1,GNA12,G3BP1,SOS1,	5.25E-2
GO:0000398	nuclear mRNA splicing, via spliceosome	CPSF7,HNRNPL,HNRNPK,SNRPC,HNRNPUL1,PRPF6,NHP2L1,	5.88E-2
GO:0000375	RNA splicing, via transesterification reactions	CPSF7,HNRNPL,HNRNPK,SNRPC,HNRNPUL1,PRPF6,NHP2L1,	5.88E-2
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	CPSF7,HNRNPL,HNRNPK,SNRPC,HNRNPUL1,PRPF6,NHP2L1,	5.88E-2
GO:0007243	protein kinase cascade	SRC,CRKL,CHUK,AKAP11,SOCS6,STAT5B,GNA12,PTK2B,JAK1,MET,AKT1,	6.22E-2
GO:0006091	generation of precursor metabolites and energy	HK1,ECH1,GAPDH,ALDOA,PPP1CB,CYB561D1,COX1,AKT1,UQCRC2,ATP5A1,	6.30E-2
GO:0010608	posttranscriptional regulation of gene expression	PTEN,CCDC88C,EIF4B,FLNA,VHL,PTK2B,AKT1,TNRC6B,	7.39E-2
GO:0043623	cellular protein complex assembly	SRC,DIAPH1,XPO1,FLNA,PTK2B,TCP1,BCS1L,	7.72E-2
GO:0042127	regulation of cell proliferation	PTEN,BCL2L1,NPM1,NOTCH1,CDK2,VHL,BLOC1S2,RB1,E2F4,ATP5A1,GJA1,PPP1CB,CUL4A,STAT5B,PTK2B,ZEB1,PLAU,	9.55E-2
GO:0031647	regulation of protein stability	PTEN,CCDC88C,FLNA,VHL,	1.00E-1

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value