ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-222

MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0004569 hsa-miR-222-5p	CUCAGUAGCCAGUGUAGAUCCU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .
MI0000299	MIPF0000051	GCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCU	MIMAT0000279 hsa-miR-222-3p	AGCUACAUCUGGCUACUGGGU	This human miRNA was predicted by computational methods using conservationwith mouse and Fugu rubripes sequences . Expression of the excised miRwas validated in zebrafish, and the ends mapped by cloning. Subsequentcloning studies have also verified the expression of miR-222 in human EScells. The mature sequence shown here represents the most commonly clonedform from large-scale cloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

SPTBN2,TMED7,ACTG1,RECK,PIGQ,DPP8,ATF5,WDR6,AUTS2,SRRM2,PCBP2,ACACA,SERTAD4,TNFSF10,USP9X
more » SPTBN2,TMED7,ACTG1,RECK,PIGQ,DPP8,ATF5,WDR6,AUTS2,SRRM2,PCBP2,ACACA,SERTAD4,TNFSF10,USP9X,ZFYVE20,ATP7B,BBC3,STOX2,PRICKLE4,LUC7L2,IRF2BP2,PRRC2A,ZMYND11,MTA2,TEX10,FASN,SHISA2,PIP5K1A,ILK,NSUN5,HDLBP,SCARB2,TRAP1,PKP2,ISG20L2,APP,NCAPD2,SEPT11,BAG6,MLL2,UBR7,RNF215,HIPK2,DMWD,C11orf57,COIL,MCM3,TNRC6B,RPS2,CKAP2,DCAF7,IPO5,ETS1,C9orf140,TRIM44,POM121,ICAM1,DIRAS3,IRAK1,TCEAL1,GCN1L1,SLC35A2,JTB,FAM126B,OGFOD1,SNTB1,IRS4,SF3B3,RPL12,POLE,ATXN7L3,TATDN2,PPM1H,STAT5A,HMGA1,PHAX,THOP1,NLE1,PFN1,HERC4,PPRC1,ENO1,DBN1,SELE,CDK4,C12orf65,EZR,FLNA,VCP,ALG3,ACTB,USP15,FUBP1,TMUB1,FAM53C,ZNF772,ZBTB7A,DAZAP1,FPGS,MEA1,KPNA6,PAK1,TLE3,MGAT4B,RNF10,HAUS8,PSMC4,UBIAD1,ESR1,PANK3,POLD2,SART1,TP53,PPP2R2A,LYN,RPS17,ATP11B,CORO1A,TOM1,GANAB,SAP30L,SKIV2L,HCFC1,C15orf23,TCEB2,NARS,DAG1,NCKAP5L,UHRF2,RFC1,EIF3B,MINK1,ERCC6L,SMC6,NKRF,NGRN,MORF4L1,QKI,HSP90AA1,KPNB1,RBM15B,CASC3,TNF,DDX21,HES1,TMCO7,TOP3A,DERA,C8orf33,TCERG1,PRDX4,EIF2S1,XPO6,TXN,EPB41L2,PARK7,TRPS1,ZW10,HEXIM1,FBXW2,GLRX5,SETD1B,CLDN23,SON,MAK16,CEP250,HEATR7A,KITLG,CDKN1C,CCDC47,PDXDC1,YY1AP1,HSPA14,MESDC2,EIF3I,GDI2,MCART1,PTDSS2,BCL2L11,RAP1GAP2,SLFN11,PKM2,PBX2,KIF4A,PELI2,CSNK1G1,CDK18,TCOF1,TMEM48,BPTF,CAST,UROD,PEBP1,OLA1,AP1B1,SDHA,ZFYVE9,PAIP2,C20orf132,CDKN1B,KIT,YWHAG,GRB10,MDN1,NOLC1,SSH2,CASKIN2,KIF5C,DBNL,MCM7,FOXO3,LGALS3BP,SLC25A36,GDI1,PTEN,AHSA1,SLC25A10,RNF4,HNRNPD,MAZ,PACS2,GTF3C5,CAPRIN1,RPL8,OSBPL10,ZNF714,MACF1,FOS,EXOSC10,FBXO21,TIMP3,DICER1,OAZ2,C9orf86,FAM83G,HDGF,PHRF1,PAN2,ZFYVE16,YLPM1,CDKL5,IPP,RBM10,TIMM50,CERS2,FYTTD1,TRMT5,NFS1,HOXA13,TLN1,HNRNPH1,SRRT,MCM3AP,EEF2,RANBP10,HIST2H4B,CSAG1,NELF,FAT1,LRP10,UBA1,PCNT,MDH2,SOD2,SMARCA4,CANX,SS18,ZNF131,IARS,PPP2R1A,EXOSC1,CBX2,PPP6C,ZNF460,VCL,ZNF770,COL5A2,MMP1,GLO1,DOCK5,SLC37A4,DAXX,DARS2,KIF3B,SORT1,POMGNT1,SEC24C,CABYR,SUN2,ADAM17,SV2A,C9orf5,MARS,PLXNB2,MAP1B

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa03030	DNA replication	MCM3,MCM7,POLD2,POLE,RFC1,	5.30E-2
hsa04530	Tight junction	PTEN,PPP2R1A,EPB41L2,CDK4,ACTG1,ACTB,PPP2R2A,CLDN23,	1.66E-1
hsa04110	Cell cycle	MCM3,MCM7,CDK4,CDKN1C,YWHAG,CDKN1B,TP53,	3.72E-1
hsa00620	Pyruvate metabolism	ACACA,MDH2,PKM2,GLO1,	4.42E-1
hsa04510	Focal adhesion	COL5A2,PTEN,TLN1,FLNA,VCL,PAK1,ACTG1,ILK,ACTB,	4.53E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0010608	posttranscriptional regulation of gene expression	QKI,GCN1L1,PTEN,SRRT,CASC3,FLNA,TNF,EIF3B,EIF2S1,CDK4,APP,HNRNPD,DICER1,PAIP2,TNRC6B,	3.48E-5
GO:0007049	cell cycle	DMWD,CEP250,SUN2,CDKN1C,PPP6C,UHRF2,CDKN1B,NOLC1,SART1,ADAM17,USP9X,HCFC1,ZMYND11,HAUS8,PCNT,MCM3,MCM7,POLE,PSMC4,TOP3A,CDK4,WDR6,ILK,SEPT11,CKAP2,NCAPD2,TP53,APP,ZW10,MACF1,DAXX,ERCC6L,	3.56E-5
GO:0046907	intracellular transport	MCM3AP,TOM1,TRPS1,TNF,FLNA,VCP,IPO5,KIF4A,KPNA6,PHAX,HSP90AA1,SEC24C,RBM15B,XPO6,SLC25A10,ZFYVE20,KPNB1,SORT1,ZFYVE9,TP53,APP,KIF3B,ATP7B,ZW10,MACF1,AP1B1,ZFYVE16,YWHAG,	7.41E-5
GO:0022402	cell cycle process	DMWD,CEP250,SUN2,CDKN1C,PPP6C,CDKN1B,SART1,NOLC1,ADAM17,USP9X,HAUS8,PCNT,POLE,PSMC4,TOP3A,CDK4,WDR6,ILK,NCAPD2,TP53,APP,ZW10,DAXX,MACF1,ERCC6L,	1.14E-4
GO:0051726	regulation of cell cycle	PTEN,SMARCA4,HOXA13,TNF,CDK4,CDKN1C,UHRF2,CDKN1B,TP53,DIRAS3,PEBP1,APP,ZW10,ADAM17,HEXIM1,ETS1,STAT5A,HCFC1,	1.31E-4

GO:0070271	protein complex biogenesis	XPO6,SOD2,KPNB1,FLNA,VCP,IPO5,ILK,HMGA1,SF3B3,SEPT11,DAG1,TP53,ZFYVE9,PEBP1,ZW10,MDN1,HSP90AA1,PPP2R1A,MAZ,NFS1,IRAK1,TCEB2,TMEM48,	1.55E-4
GO:0006461	protein complex assembly	XPO6,SOD2,KPNB1,FLNA,VCP,IPO5,ILK,HMGA1,SF3B3,SEPT11,DAG1,TP53,ZFYVE9,PEBP1,ZW10,MDN1,HSP90AA1,PPP2R1A,MAZ,NFS1,IRAK1,TCEB2,TMEM48,	1.55E-4
GO:0006606	protein import into nucleus	XPO6,MCM3AP,KPNB1,TRPS1,TNF,IPO5,KPNA6,ZFYVE9,TP53,	1.76E-4
GO:0051170	nuclear import	XPO6,MCM3AP,KPNB1,TRPS1,TNF,IPO5,KPNA6,ZFYVE9,TP53,	2.06E-4
GO:0070727	cellular macromolecule localization	XPO6,MCM3AP,KPNB1,TRPS1,TOM1,CASC3,TNF,FLNA,VCP,IPO5,SORT1,KPNA6,TP53,ZFYVE9,ZW10,MACF1,AP1B1,ZFYVE16,SEC24C,YWHAG,	2.27E-4
GO:0034504	protein localization in nucleus	XPO6,MCM3AP,KPNB1,TRPS1,TNF,IPO5,KPNA6,ZFYVE9,TP53,	3.26E-4
GO:0010629	negative regulation of gene expression	SRRT,TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,DICER1,HEXIM1,ENO1,BPTF,RBM15B,TNRC6B,ZMYND11,TCEAL1,	3.98E-4
GO:0010605	negative regulation of macromolecule metabolic process	SRRT,TRPS1,SMARCA4,CBX2,HES1,TNF,FLNA,CDKN1C,CDKN1B,NKRF,HIPK2,MTA2,PPP2R1A,ZBTB7A,DICER1,HEXIM1,RBM15B,ZMYND11,TNRC6B,PSMC4,TP53,PEBP1,DAXX,PAIP2,ENO1,BPTF,TIMP3,TCEAL1,	4.37E-4
GO:0065003	macromolecular complex assembly	FLNA,VCP,IPO5,DAG1,MDN1,PHAX,HSP90AA1,PPP2R1A,DICER1,MAZ,HIST2H4B,IRAK1,TCEB2,XPO6,SOD2,KPNB1,HMGA1,SF3B3,SEPT11,ILK,ZFYVE9,TP53,PEBP1,ZW10,NFS1,TMEM48,	5.28E-4
GO:0034613	cellular protein localization	XPO6,MCM3AP,KPNB1,TRPS1,TOM1,TNF,FLNA,VCP,IPO5,SORT1,KPNA6,TP53,ZFYVE9,ZW10,MACF1,AP1B1,ZFYVE16,SEC24C,YWHAG,	5.82E-4
GO:0045787	positive regulation of cell cycle	ADAM17,HOXA13,TNF,STAT5A,HCFC1,APP,PEBP1,	5.93E-4
GO:0043933	macromolecular complex subunit organization	FLNA,VCP,IPO5,DAG1,MDN1,PHAX,HSP90AA1,PPP2R1A,DICER1,C12orf65,MAZ,HIST2H4B,IRAK1,TCEB2,XPO6,KPNB1,SOD2,HMGA1,SF3B3,SEPT11,ILK,ZFYVE9,TP53,PEBP1,ZW10,NFS1,TMEM48,	6.02E-4
GO:0006913	nucleocytoplasmic transport	XPO6,MCM3AP,PHAX,KPNB1,TRPS1,TNF,IPO5,RBM15B,KPNA6,ZFYVE9,TP53,	6.03E-4
GO:0045859	regulation of protein kinase activity	PTEN,TNF,KIT,PAK1,CDKN1C,ILK,CDKN1B,DBNL,DIRAS3,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,	6.37E-4
GO:0051169	nuclear transport	XPO6,MCM3AP,PHAX,KPNB1,TRPS1,TNF,IPO5,RBM15B,KPNA6,ZFYVE9,TP53,	6.66E-4
GO:0008104	protein localization	MCM3AP,TOM1,TRPS1,TNF,FLNA,VCP,CEP250,IPO5,KPNA6,CANX,POM121,PHAX,SEC24C,XPO6,ZFYVE20,KPNB1,SORT1,ZFYVE9,TP53,ZW10,MACF1,AP1B1,EZR,GDI1,GDI2,ZFYVE16,TLN1,TIMM50,YWHAG,LYN,TMEM48,	7.75E-4
GO:0006917	induction of apoptosis	PTEN,FOXO3,TNF,TNFSF10,CDKN1B,SORT1,SART1,TP53,APP,DAXX,HIPK2,BBC3,PPP2R1A,ETS1,TIMP3,BCL2L11,	8.43E-4
GO:0012502	induction of programmed cell death	PTEN,FOXO3,TNF,TNFSF10,CDKN1B,SORT1,SART1,TP53,APP,DAXX,HIPK2,BBC3,PPP2R1A,ETS1,TIMP3,BCL2L11,	8.68E-4
GO:0045892	negative regulation of transcription, DNA-dependent	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,BPTF,ZMYND11,TCEAL1,	8.91E-4
GO:0045184	establishment of protein localization	MCM3AP,TOM1,TRPS1,TNF,FLNA,VCP,IPO5,KPNA6,CANX,POM121,PHAX,SEC24C,XPO6,ZFYVE20,KPNB1,SORT1,ZFYVE9,TP53,ZW10,MACF1,AP1B1,GDI1,GDI2,ZFYVE16,TIMM50,YWHAG,LYN,TMEM48,	9.02E-4
GO:0043549	regulation of kinase activity	PTEN,TNF,KIT,PAK1,CDKN1C,ILK,CDKN1B,DBNL,DIRAS3,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,	9.18E-4
GO:0006417	regulation of translation	QKI,GCN1L1,CASC3,TNF,PAIP2,EIF3B,EIF2S1,CDK4,TNRC6B,APP,	9.45E-4
GO:0042325	regulation of phosphorylation	PTEN,MCM7,TNF,KIT,CDKN1C,PAK1,ILK,CDKN1B,DBNL,DIRAS3,PEBP1,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,LYN,	9.76E-4
GO:0051253	negative regulation of RNA metabolic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,BPTF,ZMYND11,TCEAL1,	1.06E-2
GO:0007010	cytoskeleton organization	HAUS8,PCNT,CORO1A,SS18,FLNA,CEP250,SUN2,PAK1,ZW10,EZR,MACF1,DBN1,TLN1,EPB41L2,SSH2,ACTG1,RANBP10,MAP1B,PFN1,	1.14E-2
GO:0032268	regulation of cellular protein metabolic process	QKI,GCN1L1,CASC3,TNF,PSMC4,EIF3B,EIF2S1,CDK4,PAK1,DBNL,PEBP1,APP,DAXX,ADAM17,KITLG,PPP2R1A,PAIP2,TIMP3,LYN,TNRC6B,	1.20E-2
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	HES1,CBX2,SMARCA4,TNF,CDKN1C,TP53,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,BPTF,ZMYND11,TCEAL1,	1.27E-2
GO:0051338	regulation of transferase activity	PTEN,TNF,KIT,PAK1,CDKN1C,ILK,CDKN1B,DBNL,DIRAS3,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,	1.41E-2
GO:0033365	protein localization in organelle	XPO6,MCM3AP,MACF1,KPNB1,TRPS1,TNF,IPO5,KPNA6,ZFYVE9,TP53,	1.47E-2
GO:0006886	intracellular protein transport	XPO6,MCM3AP,KPNB1,TRPS1,TOM1,TNF,VCP,IPO5,SORT1,KPNA6,TP53,ZFYVE9,MACF1,AP1B1,ZFYVE16,SEC24C,YWHAG,	1.49E-2
GO:0006607	NLS-bearing substrate import into nucleus	KPNB1,TRPS1,IPO5,KPNA6,	1.51E-2
GO:0019220	regulation of phosphate metabolic process	PTEN,MCM7,TNF,KIT,CDKN1C,PAK1,ILK,CDKN1B,DBNL,DIRAS3,PEBP1,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,LYN,	1.52E-2
GO:0051174	regulation of phosphorus metabolic process	PTEN,MCM7,TNF,KIT,CDKN1C,PAK1,ILK,CDKN1B,DBNL,DIRAS3,PEBP1,APP,DAXX,ADAM17,KITLG,PPP2R1A,HEXIM1,YWHAG,IRAK1,LYN,	1.52E-2
GO:0015031	protein transport	MCM3AP,TOM1,TRPS1,TNF,VCP,IPO5,KPNA6,CANX,POM121,PHAX,SEC24C,XPO6,ZFYVE20,KPNB1,SORT1,ZFYVE9,TP53,ZW10,AP1B1,MACF1,GDI1,GDI2,ZFYVE16,TIMM50,YWHAG,LYN,TMEM48,	1.67E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	PBX2,SOD2,SMARCA4,ATXN7L3,FOXO3,HES1,TNF,HOXA13,HMGA1,TP53,PEBP1,APP,ICAM1,HIPK2,KITLG,RNF4,RNF10,HSP90AA1,MTA2,STAT5A,ETS1,BPTF,FOS,IRAK1,	1.74E-2
GO:0045637	regulation of myeloid cell differentiation	KITLG,ZBTB7A,FOXO3,TNF,ETS1,STAT5A,HIST2H4B,	1.75E-2
GO:0043067	regulation of programmed cell death	TNF,VCP,TNFSF10,CDKN1B,ESR1,SART1,HIPK2,ADAM17,BBC3,PPP2R1A,ATF5,BCL2L11,IRAK1,PTEN,SOD2,FOXO3,HOXA13,KIT,ILK,SORT1,TP53,APP,GLO1,DAXX,STAT5A,ETS1,TIMP3,SON,	1.98E-2
GO:0016481	negative regulation of transcription	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,RBM15B,BPTF,ZMYND11,TCEAL1,	2.02E-2
GO:0006605	protein targeting	XPO6,MCM3AP,MACF1,KPNB1,TRPS1,ZFYVE16,TNF,YWHAG,IPO5,KPNA6,ZFYVE9,TP53,	2.07E-2
GO:0010941	regulation of cell death	TNF,VCP,TNFSF10,CDKN1B,ESR1,SART1,HIPK2,ADAM17,BBC3,PPP2R1A,ATF5,BCL2L11,IRAK1,PTEN,SOD2,FOXO3,HOXA13,KIT,ILK,SORT1,TP53,APP,GLO1,DAXX,STAT5A,ETS1,TIMP3,SON,	2.08E-2
GO:0042493	response to drug	PARK7,PTEN,ADAM17,SOD2,FPGS,SS18,ACACA,FOS,LYN,MAP1B,TP53,PEBP1,	2.14E-2
GO:0010627	regulation of protein kinase cascade	PTEN,TMED7,FLNA,TNF,PAK1,TNFSF10,ILK,DBNL,PEBP1,DAXX,HIPK2,PPP2R1A,LYN,	2.18E-2
GO:0007017	microtubule-based process	HAUS8,PCNT,KIF5C,SS18,CEP250,SUN2,KIF4A,KIF3B,APP,ZW10,MACF1,RANBP10,MAP1B,	2.48E-2
GO:0006396	RNA processing	SRRM2,QKI,SRRT,EXOSC1,CASC3,RPS17,PCBP2,SF3B3,NOLC1,SART1,RBM10,APP,HNRNPH1,EXOSC10,PHAX,PHRF1,HNRNPD,PPP2R1A,DICER1,TRMT5,RBM15B,	2.62E-2
GO:0017038	protein import	XPO6,MCM3AP,KPNB1,TRPS1,TNF,IPO5,KPNA6,ZFYVE9,TP53,	2.84E-2
GO:0000079	regulation of cyclin-dependent protein kinase activity	PTEN,ADAM17,HEXIM1,CDKN1C,CDKN1B,DIRAS3,	3.02E-2
GO:0000278	mitotic cell cycle	HAUS8,POLE,PSMC4,CEP250,SUN2,PPP6C,CDKN1C,CDK4,CDKN1B,NOLC1,NCAPD2,APP,ZW10,ADAM17,USP9X,ERCC6L,	3.46E-2
GO:0042981	regulation of apoptosis	TNF,VCP,TNFSF10,CDKN1B,ESR1,SART1,HIPK2,ADAM17,BBC3,PPP2R1A,ATF5,BCL2L11,IRAK1,PTEN,SOD2,FOXO3,HOXA13,ILK,SORT1,TP53,APP,GLO1,DAXX,ETS1,STAT5A,TIMP3,SON,	3.49E-2
GO:0010033	response to organic substance	SRRT,CORO1A,TNF,SELE,SLC25A36,VCP,ESR1,PPP2R2A,ADAM17,HSP90AA1,PPP2R1A,DICER1,SKIV2L,IRAK1,MAP1B,PTEN,SORT1,PEBP1,ATP7B,GRB10,ACACA,STAT5A,FOS,TIMP3,LYN,	3.49E-2
GO:0050767	regulation of neurogenesis	DBN1,HES1,PLXNB2,KIT,YWHAG,ILK,ATF5,LYN,MAP1B,TP53,	3.53E-2
GO:0031328	positive regulation of cellular biosynthetic process	PBX2,SOD2,SMARCA4,ATXN7L3,FOXO3,HES1,TNF,HOXA13,CDK4,HMGA1,TP53,APP,ICAM1,HIPK2,KITLG,RNF4,RNF10,HSP90AA1,MTA2,STAT5A,ETS1,BPTF,FOS,IRAK1,	3.78E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	PBX2,SMARCA4,CBX2,HES1,TNF,CDKN1C,HIPK2,RNF4,MTA2,ZBTB7A,HEXIM1,ATF5,ZMYND11,SOD2,FOXO3,HOXA13,TP53,APP,ETS1,STAT5A,ENO1,BPTF,FOS,PFN1,TCEAL1,	3.81E-2
GO:0033554	cellular response to stress	SOD2,SMC6,MCM7,POLD2,FOXO3,POLE,TNF,RFC1,VCP,EIF2S1,DBNL,TP53,MORF4L1,DAXX,HIPK2,MINK1,BBC3,CCDC47,FOS,MAP1B,LYN,	3.87E-2
GO:0008088	axon cargo transport	MACF1,KIF4A,APP,KIF3B,	4.05E-2
GO:0022403	cell cycle phase	HAUS8,PCNT,POLE,DMWD,TOP3A,SUN2,CDK4,PPP6C,CDKN1C,CDKN1B,NOLC1,NCAPD2,APP,ZW10,ADAM17,USP9X,ERCC6L,	4.06E-2
GO:0006261	DNA-dependent DNA replication	MCM3,MCM7,POLD2,RFC1,TOP3A,HMGA1,	4.13E-2
GO:0009891	positive regulation of biosynthetic process	PBX2,SOD2,SMARCA4,ATXN7L3,FOXO3,HES1,TNF,HOXA13,CDK4,HMGA1,TP53,APP,ICAM1,HIPK2,KITLG,RNF4,RNF10,HSP90AA1,MTA2,STAT5A,ETS1,BPTF,FOS,IRAK1,	4.51E-2
GO:0010628	positive regulation of gene expression	PBX2,SMARCA4,FOXO3,HES1,ATXN7L3,TNF,HOXA13,KIT,HMGA1,ESR1,TP53,APP,HIPK2,RNF4,RNF10,MTA2,STAT5A,ETS1,BPTF,FOS,IRAK1,	5.16E-2
GO:0000226	microtubule cytoskeleton organization	ZW10,HAUS8,MACF1,PCNT,SS18,CEP250,SUN2,RANBP10,MAP1B,	5.71E-2
GO:0010558	negative regulation of macromolecule biosynthetic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,PAIP2,ENO1,BPTF,RBM15B,ZMYND11,TCEAL1,	5.77E-2
GO:0043065	positive regulation of apoptosis	PTEN,FOXO3,TNF,HOXA13,TNFSF10,CDKN1B,SORT1,SART1,TP53,APP,DAXX,HIPK2,BBC3,PPP2R1A,ETS1,TIMP3,BCL2L11,	5.87E-2
GO:0043068	positive regulation of programmed cell death	PTEN,FOXO3,TNF,HOXA13,TNFSF10,CDKN1B,SORT1,SART1,TP53,APP,DAXX,HIPK2,BBC3,PPP2R1A,ETS1,TIMP3,BCL2L11,	6.24E-2
GO:0045429	positive regulation of nitric oxide biosynthetic process	SOD2,HSP90AA1,TNF,ICAM1,	6.34E-2
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,RBM15B,BPTF,ZMYND11,TCEAL1,	6.35E-2
GO:0043069	negative regulation of programmed cell death	PTEN,SOD2,TNF,KIT,ESR1,ILK,SORT1,TP53,GLO1,HIPK2,ADAM17,STAT5A,ATF5,IRAK1,SON,	6.44E-2
GO:0010942	positive regulation of cell death	PTEN,FOXO3,TNF,HOXA13,TNFSF10,CDKN1B,SORT1,SART1,TP53,APP,DAXX,HIPK2,BBC3,PPP2R1A,ETS1,TIMP3,BCL2L11,	6.52E-2
GO:0060548	negative regulation of cell death	PTEN,SOD2,TNF,KIT,ESR1,ILK,SORT1,TP53,GLO1,HIPK2,ADAM17,STAT5A,ATF5,IRAK1,SON,	6.69E-2
GO:0051172	negative regulation of nitrogen compound metabolic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,ENO1,RBM15B,BPTF,ZMYND11,TCEAL1,	7.24E-2
GO:0031327	negative regulation of cellular biosynthetic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,PAIP2,ENO1,BPTF,RBM15B,ZMYND11,TCEAL1,	7.46E-2
GO:0010604	positive regulation of macromolecule metabolic process	PBX2,SMARCA4,HES1,TNF,SELE,ESR1,HIPK2,ADAM17,KITLG,RNF4,MTA2,IRAK1,FOXO3,ATXN7L3,HOXA13,PSMC4,KIT,CDK4,HMGA1,TP53,APP,RNF10,STAT5A,ETS1,BPTF,FOS,LYN,	7.90E-2
GO:0016071	mRNA metabolic process	QKI,SRRM2,CASC3,PAN2,PCBP2,SF3B3,SART1,RBM10,APP,HNRNPH1,EXOSC10,PHAX,PHRF1,HNRNPD,RBM15B,	8.41E-2
GO:0070302	regulation of stress-activated protein kinase signaling pathway	DAXX,HIPK2,TNF,PAK1,LYN,DBNL,	8.61E-2
GO:0051960	regulation of nervous system development	DBN1,HES1,PLXNB2,KIT,YWHAG,ILK,ATF5,LYN,MAP1B,TP53,	8.99E-2
GO:0051272	positive regulation of cell motion	ADAM17,CORO1A,ETS1,KIT,ILK,LYN,ICAM1,	9.25E-2
GO:0051270	regulation of cell motion	PTEN,ADAM17,CORO1A,VCL,ETS1,KIT,CDKN1B,ILK,LYN,ICAM1,	9.29E-2
GO:0009890	negative regulation of biosynthetic process	TRPS1,SMARCA4,HES1,CBX2,TNF,CDKN1C,CDKN1B,TP53,NKRF,DAXX,HIPK2,MTA2,ZBTB7A,HEXIM1,PAIP2,ENO1,BPTF,RBM15B,ZMYND11,TCEAL1,	9.31E-2
GO:0045449	regulation of transcription	FUBP1,ZNF460,SMARCA4,HES1,CBX2,TNF,ESR1,ICAM1,SAP30L,HEXIM1,MAZ,RBM15B,TCEB2,HCFC1,CERS2,SOD2,SETD1B,RFC1,HOXA13,TCERG1,DAXX,RNF10,HNRNPD,ZNF131,STAT5A,ETS1,ENO1,PFN1,PBX2,ZNF714,TRPS1,FLNA,CDKN1C,CDKN1B,NKRF,IRF2BP2,HIPK2,RNF4,MTA2,ZBTB7A,PPP2R1A,ATF5,IRAK1,ZMYND11,ZNF708,ZNF772,MCM3,MCM7,FOXO3,ATXN7L3,SS18,YY1AP1,HMGA1,TP53,APP,MLL2,MORF4L1,ZNF770,HDGF,FOS,PPRC1,BPTF,TLE3,TCEAL1,	9.56E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value