ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-22

MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0004495 hsa-miR-22-5p	AGUUCUUCAGUGGCAAGCUUUA
MI0000078	MIPF0000053	GGCUGAGCCGCAGUAGUUCUUCAGUGGCAAGCUUUAUGUCCUGACCCAGCUAAAGCUGCCAGUUGAAGAACUGUUGCCCUCUGCC	MIMAT0000077 hsa-miR-22-3p	AAGCUGCCAGUUGAAGAACUGU

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

CREBBP,SLC35B2,CCDC113,FUBP1,VAPB,ESR1,MAOA,TBX3,RPL10,H3F3B,HNRNPA1,HDAC4,C17orf81,RGS2,FKBP5
more » CREBBP,SLC35B2,CCDC113,FUBP1,VAPB,ESR1,MAOA,TBX3,RPL10,H3F3B,HNRNPA1,HDAC4,C17orf81,RGS2,FKBP5,KIAA0889,BMP7,SP1,RCOR1,LEMD3,PEX5,MIS18BP1,STX4,CSNK2A1,HDAC6,RAN,RAB5B,ALMS1,SIRT1,FRAT2,NUP214,NCOA1,NR3C1,RBM39,SFXN1,ZNF217,CCNT2,HTR2C,LRRC1,RPL24,PTMS,LIN7C,PIK3C2A,SMCR7L,ZFYVE20,DNHD1,SPG11,ARID5B,BCLAF1,RPS4X,CDKN1A,GLIS2,IRF5,FOXP1,MYCBP,PDHA1,ACVR1C,RPL35A,LBP,BTF3,ARPC5,C5orf24,BUB1B,ERBB3,SRSF7,CDK6,E2F2,HMGB1,BDNF,RAD51,PRKACA,RPS2,TCEAL1,MYO6,TSC22D4,RPSA,CLPTM1L,TFRC,PPARA,KCTD12,PTEN,EDC3,TBC1D12

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa03010	Ribosome	RPL10,RPSA,RPS4X,RPL35A,RPL24,RPS2,	5.36E-4
hsa05214	Glioma	CDK6,PTEN,CDKN1A,E2F2,	1.29E-1
hsa04144	Endocytosis	HSPA1B,ZFYVE20,ERBB3,TFRC,RAB5B,ACVR1C,	1.38E-1
hsa04110	Cell cycle	CDK6,CREBBP,BUB1B,CDKN1A,E2F2,	1.60E-1
hsa05218	Melanoma	CDK6,PTEN,CDKN1A,E2F2,	1.78E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0010033	response to organic substance	HSPA1B,PTEN,ERBB3,TFRC,NR3C1,PRKACA,HDAC4,ACVR1C,ESR1,CDKN1A,BMP7,PPARA,HTR2C,LBP,HDAC6,VAPB,	1.10E-5
GO:0018205	peptidyl-lysine modification	CREBBP,HDAC6,HDAC4,SIRT1,	1.13E-4
GO:0045449	regulation of transcription	FUBP1,BTF3,HMGB1,ESR1,FOXP1,PPARA,NCOA1,BCLAF1,ARID5B,CREBBP,HDAC6,MYCBP,TSC22D4,TBX3,C17orf81,NR3C1,GLIS2,HDAC4,ZNF217,BMP7,SP1,RAN,E2F2,RCOR1,RBM39,MYO6,CCNT2,IRF5,SIRT1,TCEAL1,	1.21E-4
GO:0006350	transcription	FUBP1,BTF3,ESR1,FOXP1,PPARA,NCOA1,BCLAF1,ARID5B,CREBBP,HDAC6,TSC22D4,MYCBP,TBX3,C17orf81,NR3C1,GLIS2,HDAC4,ZNF217,SP1,E2F2,RCOR1,RBM39,CCNT2,IRF5,SIRT1,TCEAL1,	1.60E-4
GO:0034983	peptidyl-lysine deacetylation	HDAC6,HDAC4,SIRT1,	1.90E-4

GO:0045596	negative regulation of cell differentiation	PPARA,CDK6,CREBBP,BDNF,HDAC4,BMP7,SIRT1,TBX3,	2.23E-4
GO:0006414	translational elongation	RPL10,RPSA,RPS4X,RPL35A,RPL24,RPS2,	2.71E-4
GO:0042981	regulation of apoptosis	HSPA1B,PTEN,ERBB3,HMGB1,NR3C1,ACVR1C,ESR1,CDKN1A,BMP7,BCLAF1,HDAC6,BDNF,TBX3,SIRT1,	5.58E-4
GO:0051726	regulation of cell cycle	CDK6,PTEN,BUB1B,CCNT2,RPL24,CDKN1A,BMP7,TBX3,E2F2,	5.72E-4
GO:0043067	regulation of programmed cell death	HSPA1B,PTEN,ERBB3,HMGB1,NR3C1,ACVR1C,ESR1,CDKN1A,BMP7,BCLAF1,HDAC6,BDNF,TBX3,SIRT1,	6.13E-4
GO:0010941	regulation of cell death	HSPA1B,PTEN,ERBB3,HMGB1,NR3C1,ACVR1C,ESR1,CDKN1A,BMP7,BCLAF1,HDAC6,BDNF,TBX3,SIRT1,	6.35E-4
GO:0010604	positive regulation of macromolecule metabolic process	GLIS2,HDAC4,ESR1,SP1,BMP7,RAN,PPARA,NCOA1,CREBBP,HDAC6,MYO6,RAD51,RPS4X,TBX3,	1.01E-2
GO:0010557	positive regulation of macromolecule biosynthetic process	PPARA,NCOA1,CREBBP,HDAC6,GLIS2,MYO6,HDAC4,RPS4X,BMP7,SP1,RAN,TBX3,	1.12E-2
GO:0016481	negative regulation of transcription	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	1.14E-2
GO:0006351	transcription, DNA-dependent	FUBP1,PPARA,BTF3,NR3C1,ZNF217,CCNT2,ESR1,E2F2,	1.34E-2
GO:0003001	generation of a signal involved in cell-cell signaling	STX4,LIN7C,BDNF,MYO6,TBX3,	1.38E-2
GO:0032774	RNA biosynthetic process	FUBP1,PPARA,BTF3,NR3C1,ZNF217,CCNT2,ESR1,E2F2,	1.45E-2
GO:0009991	response to extracellular stimulus	PPARA,PTEN,HDAC6,TFRC,CDKN1A,BMP7,SIRT1,	1.56E-2
GO:0010628	positive regulation of gene expression	PPARA,NCOA1,CREBBP,GLIS2,MYO6,HDAC4,ESR1,BMP7,SP1,RAN,TBX3,	1.62E-2
GO:0009891	positive regulation of biosynthetic process	PPARA,NCOA1,CREBBP,HDAC6,GLIS2,MYO6,HDAC4,RPS4X,BMP7,SP1,RAN,TBX3,	1.83E-2
GO:0007423	sensory organ development	ERBB3,BDNF,ALMS1,MYO6,RPL24,BMP7,SP1,	1.92E-2
GO:0009719	response to endogenous stimulus	PPARA,PTEN,ERBB3,HDAC6,PRKACA,ACVR1C,ESR1,CDKN1A,BMP7,	2.08E-2
GO:0010629	negative regulation of gene expression	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	2.18E-2
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	2.43E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	PPARA,NCOA1,HMGB1,CREBBP,MYO6,HDAC4,FOXP1,BMP7,SP1,SIRT1,TBX3,TCEAL1,	2.61E-2
GO:0051172	negative regulation of nitrogen compound metabolic process	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	2.66E-2
GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	PPARA,NCOA1,CREBBP,GLIS2,MYO6,HDAC4,RAD51,BMP7,SP1,RAN,TBX3,	2.73E-2
GO:0010605	negative regulation of macromolecule metabolic process	PPARA,BCLAF1,ARID5B,HMGB1,HDAC6,GLIS2,HDAC4,BUB1B,FOXP1,SIRT1,TBX3,TCEAL1,	2.81E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	PPARA,NCOA1,CREBBP,GLIS2,MYO6,HDAC4,RAD51,BMP7,SP1,RAN,TBX3,	3.43E-2
GO:0010558	negative regulation of macromolecule biosynthetic process	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	3.77E-2
GO:0043066	negative regulation of apoptosis	HSPA1B,PTEN,ERBB3,HMGB1,BDNF,ESR1,CDKN1A,TBX3,	3.96E-2
GO:0045892	negative regulation of transcription, DNA-dependent	PPARA,ARID5B,HMGB1,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	4.08E-2
GO:0016575	histone deacetylation	HDAC6,HDAC4,SIRT1,	4.11E-2
GO:0006355	regulation of transcription, DNA-dependent	HMGB1,NR3C1,HDAC4,ESR1,FOXP1,BMP7,SP1,RAN,E2F2,PPARA,NCOA1,ARID5B,CREBBP,HDAC6,TSC22D4,MYO6,IRF5,SIRT1,TBX3,TCEAL1,	4.20E-2
GO:0043069	negative regulation of programmed cell death	HSPA1B,PTEN,ERBB3,HMGB1,BDNF,ESR1,CDKN1A,TBX3,	4.27E-2
GO:0060548	negative regulation of cell death	HSPA1B,PTEN,ERBB3,HMGB1,BDNF,ESR1,CDKN1A,TBX3,	4.34E-2
GO:0030518	steroid hormone receptor signaling pathway	NCOA1,NR3C1,ESR1,RAN,	4.36E-2
GO:0031327	negative regulation of cellular biosynthetic process	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	4.45E-2
GO:0051253	negative regulation of RNA metabolic process	PPARA,ARID5B,HMGB1,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	4.47E-2
GO:0045941	positive regulation of transcription	PPARA,NCOA1,CREBBP,GLIS2,MYO6,HDAC4,BMP7,SP1,RAN,TBX3,	4.61E-2
GO:0009725	response to hormone stimulus	PPARA,PTEN,ERBB3,PRKACA,ACVR1C,ESR1,CDKN1A,BMP7,	4.81E-2
GO:0009890	negative regulation of biosynthetic process	PPARA,BCLAF1,ARID5B,HMGB1,GLIS2,HDAC4,FOXP1,SIRT1,TBX3,TCEAL1,	5.11E-2
GO:0031667	response to nutrient levels	PPARA,PTEN,HDAC6,TFRC,BMP7,SIRT1,	5.27E-2
GO:0031328	positive regulation of cellular biosynthetic process	PPARA,NCOA1,CREBBP,GLIS2,MYO6,HDAC4,RPS4X,BMP7,SP1,RAN,TBX3,	5.29E-2
GO:0051252	regulation of RNA metabolic process	HMGB1,NR3C1,HDAC4,ESR1,FOXP1,BMP7,SP1,RAN,E2F2,PPARA,NCOA1,ARID5B,CREBBP,HDAC6,TSC22D4,MYO6,IRF5,SIRT1,TBX3,TCEAL1,	5.38E-2
GO:0045893	positive regulation of transcription, DNA-dependent	PPARA,NCOA1,CREBBP,MYO6,HDAC4,BMP7,SP1,RAN,TBX3,	5.63E-2
GO:0006325	chromatin organization	RCOR1,H3F3B,HMGB1,CREBBP,HDAC6,NR3C1,HDAC4,SIRT1,	5.64E-2
GO:0051254	positive regulation of RNA metabolic process	PPARA,NCOA1,CREBBP,MYO6,HDAC4,BMP7,SP1,RAN,TBX3,	5.91E-2
GO:0006476	protein amino acid deacetylation	HDAC6,HDAC4,SIRT1,	6.86E-2
GO:0042493	response to drug	HTR2C,PTEN,ERBB3,BDNF,HDAC4,CDKN1A,	7.72E-2
GO:0021675	nerve development	ERBB3,BDNF,RPL24,	8.81E-2
GO:0030522	intracellular receptor-mediated signaling pathway	NCOA1,NR3C1,ESR1,RAN,	8.92E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value