Gene ontology terms enriched for interacted genes |
GO terms | GO terms description | target genes enrich in GO term | p-value |
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GO:0007389
|
pattern specification process |
TCF7L1,HOXB5,ACVR2B,EP300,BMI1,FLT1,GATA4,ZEB2,EDNRA,RNF2,VEGFA,TGFBR1,ZEB1, |
2.18E-10 |
GO:0035295
|
tube development |
EDNRA,BCL2,VEGFA,ACVR2B,EP300,FLT1,ZFPM2,GATA4,TGFBR1,ZEB2, |
1.13E-7 |
GO:0010647
|
positive regulation of cell communication |
JAG1,VEGFA,ACVR2B,RHOA,FLT1,FLNA,LPAR1,NTRK2,TGFBR1,ZEB2,TBK1, |
3.32E-7 |
GO:0003002
|
regionalization |
RNF2,ACVR2B,TCF7L1,HOXB5,BMI1,EP300,GATA4,TGFBR1,ZEB2, |
6.53E-7 |
GO:0009952
|
anterior/posterior pattern formation |
RNF2,ACVR2B,TCF7L1,HOXB5,EP300,GATA4,TGFBR1,ZEB2, |
8.65E-7 |
|
GO:0009967
|
positive regulation of signal transduction |
JAG1,VEGFA,ACVR2B,RHOA,FLT1,FLNA,LPAR1,TGFBR1,ZEB2,TBK1, |
1.34E-6 |
GO:0044093
|
positive regulation of molecular function |
EDNRA,BCL2,ACVR2B,EP300,SHC1,FLT1,IKBKB,LPAR1,NTRK2,TGFBR1,ZEB2,PMAIP1, |
8.99E-6 |
GO:0070482
|
response to oxygen levels |
ATP6,EDNRA,BCL2,VEGFA,EP300,FLT1,TGFBR1, |
1.41E-5 |
GO:0045449
|
regulation of transcription |
KLF9,ILF3,ACVR2B,HOXB5,RCOR3,TCF7L1,BMI1,EP300,FLNA,IKBKB,UBE2I,GATA4,ZEB2,ZNF416,RNF2,VEGFA,RHOA,KLF11,BRD7,USP22,NTF3,ZFPM2,TGFBR1,ZEB1, |
2.22E-5 |
GO:0007167
|
enzyme linked receptor protein signaling pathway |
VEGFA,ERBB2IP,ACVR2B,SHC1,FLT1,FLNA,NTRK2,TGFBR1,PTPRD, |
3.79E-5 |
GO:0010604
|
positive regulation of macromolecule metabolic process |
ILF3,BCL2,TCF7L1,SHC1,EP300,GATA4,EDNRA,VEGFA,USP22,NTF3,ZFPM2,TGFBR1,ZEB1, |
6.16E-5 |
GO:0006357
|
regulation of transcription from RNA polymerase II promoter |
KLF9,RNF2,VEGFA,RHOA,TCF7L1,KLF11,EP300,BRD7,NTF3,ZFPM2,GATA4,ZEB1, |
6.61E-5 |
GO:0045935
|
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
ILF3,VEGFA,TCF7L1,EP300,SHC1,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
9.33E-5 |
GO:0035239
|
tube morphogenesis |
EDNRA,BCL2,VEGFA,FLT1,GATA4,ZEB2, |
1.12E-4 |
GO:0051173
|
positive regulation of nitrogen compound metabolic process |
ILF3,VEGFA,TCF7L1,EP300,SHC1,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
1.21E-4 |
GO:0043085
|
positive regulation of catalytic activity |
EDNRA,BCL2,ACVR2B,SHC1,FLT1,LPAR1,NTRK2,TGFBR1,ZEB2,PMAIP1, |
1.23E-4 |
GO:0048514
|
blood vessel morphogenesis |
EDNRA,JAG1,VEGFA,FLT1,ZFPM2,NTRK2,TGFBR1, |
1.34E-4 |
GO:0042127
|
regulation of cell proliferation |
EDNRA,BCL2,JAG1,VEGFA,BAP1,KLF11,BMI1,SHC1,FLT1,GATA4,TGFBR1,ZEB1, |
1.34E-4 |
GO:0010557
|
positive regulation of macromolecule biosynthetic process |
ILF3,VEGFA,TCF7L1,EP300,SHC1,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
1.37E-4 |
GO:0001666
|
response to hypoxia |
EDNRA,BCL2,VEGFA,EP300,FLT1,TGFBR1, |
1.44E-4 |
GO:0045860
|
positive regulation of protein kinase activity |
EDNRA,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
1.81E-4 |
GO:0031328
|
positive regulation of cellular biosynthetic process |
ILF3,VEGFA,TCF7L1,EP300,SHC1,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
2.00E-4 |
GO:0033674
|
positive regulation of kinase activity |
EDNRA,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
2.20E-4 |
GO:0009891
|
positive regulation of biosynthetic process |
ILF3,VEGFA,TCF7L1,EP300,SHC1,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
2.25E-4 |
GO:0043009
|
chordate embryonic development |
EDNRA,HOXB5,EP300,ZFPM2,GATA4,TGFBR1,ZEB2,ZEB1, |
2.26E-4 |
GO:0045941
|
positive regulation of transcription |
ILF3,VEGFA,TCF7L1,EP300,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
2.26E-4 |
GO:0009792
|
embryonic development ending in birth or egg hatching |
EDNRA,HOXB5,EP300,ZFPM2,GATA4,TGFBR1,ZEB2,ZEB1, |
2.38E-4 |
GO:0051347
|
positive regulation of transferase activity |
EDNRA,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
2.70E-4 |
GO:0010628
|
positive regulation of gene expression |
ILF3,VEGFA,TCF7L1,EP300,USP22,NTF3,ZFPM2,GATA4,TGFBR1,ZEB1, |
2.82E-4 |
GO:0045859
|
regulation of protein kinase activity |
EDNRA,CCNE2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
2.91E-4 |
GO:0001568
|
blood vessel development |
EDNRA,JAG1,VEGFA,FLT1,ZFPM2,NTRK2,TGFBR1, |
3.02E-4 |
GO:0042325
|
regulation of phosphorylation |
EDNRA,CCNE2,BCL2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
3.22E-4 |
GO:0010627
|
regulation of protein kinase cascade |
RHOA,FLNA,IKBKB,LPAR1,TGFBR1,ZEB2,TBK1, |
3.29E-4 |
GO:0048565
|
gut development |
BCL2,ACVR2B,GATA4,TGFBR1, |
3.30E-4 |
GO:0001944
|
vasculature development |
EDNRA,JAG1,VEGFA,FLT1,ZFPM2,NTRK2,TGFBR1, |
3.43E-4 |
GO:0043549
|
regulation of kinase activity |
EDNRA,CCNE2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
3.58E-4 |
GO:0051174
|
regulation of phosphorus metabolic process |
EDNRA,CCNE2,BCL2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
4.22E-4 |
GO:0019220
|
regulation of phosphate metabolic process |
EDNRA,CCNE2,BCL2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
4.22E-4 |
GO:0051338
|
regulation of transferase activity |
EDNRA,CCNE2,ACVR2B,SHC1,FLT1,LPAR1,TGFBR1,ZEB2, |
4.58E-4 |
GO:0048568
|
embryonic organ development |
VEGFA,HOXB5,ZFPM2,GATA4,TGFBR1,ZEB1, |
4.58E-4 |
GO:0030324
|
lung development |
VEGFA,ACVR2B,EP300,ZFPM2,TGFBR1, |
5.18E-4 |
GO:0007049
|
cell cycle |
SEPT7,RNF2,CCNE2,ILF3,BCL2,TUBB3,ERBB2IP,EP300,USP22,UBE2I,RASSF2, |
5.43E-4 |
GO:0006355
|
regulation of transcription, DNA-dependent |
KLF9,ILF3,TCF7L1,HOXB5,EP300,UBE2I,GATA4,ZEB2,ZNF416,RNF2,VEGFA,RHOA,KLF11,BRD7,NTF3,ZFPM2,ZEB1, |
5.53E-4 |
GO:0030323
|
respiratory tube development |
VEGFA,ACVR2B,EP300,ZFPM2,TGFBR1, |
5.79E-4 |
GO:0045934
|
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
EDNRA,RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
6.04E-4 |
GO:0051172
|
negative regulation of nitrogen compound metabolic process |
EDNRA,RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
6.60E-4 |
GO:0043122
|
regulation of I-kappaB kinase/NF-kappaB cascade |
RHOA,FLNA,IKBKB,LPAR1,TBK1, |
6.94E-4 |
GO:0051252
|
regulation of RNA metabolic process |
KLF9,ILF3,TCF7L1,HOXB5,EP300,UBE2I,GATA4,ZEB2,ZNF416,RNF2,VEGFA,RHOA,KLF11,BRD7,NTF3,ZFPM2,ZEB1, |
7.11E-4 |
GO:0060541
|
respiratory system development |
VEGFA,ACVR2B,EP300,ZFPM2,TGFBR1, |
7.19E-4 |
GO:0035282
|
segmentation |
TCF7L1,BMI1,EP300,ZEB2, |
7.74E-4 |
GO:0006793
|
phosphorus metabolic process |
ATP6,PTPN13,BCL2,ACVR2B,SHC1,FLT1,IKBKB,LPAR1,NTRK2,TGFBR1,TBK1,PTPRD, |
8.32E-4 |
GO:0006796
|
phosphate metabolic process |
ATP6,PTPN13,BCL2,ACVR2B,SHC1,FLT1,IKBKB,LPAR1,NTRK2,TGFBR1,TBK1,PTPRD, |
8.32E-4 |
GO:0048598
|
embryonic morphogenesis |
RNF2,ACVR2B,HOXB5,GATA4,TGFBR1,ZEB2,ZEB1, |
9.92E-4 |
GO:0031327
|
negative regulation of cellular biosynthetic process |
EDNRA,RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
1.09E-2 |
GO:0007507
|
heart development |
EDNRA,ACVR2B,EP300,ZFPM2,GATA4,TGFBR1, |
1.25E-2 |
GO:0009890
|
negative regulation of biosynthetic process |
EDNRA,RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
1.25E-2 |
GO:0007169
|
transmembrane receptor protein tyrosine kinase signaling pathway |
VEGFA,ERBB2IP,SHC1,FLT1,FLNA,NTRK2, |
1.50E-2 |
GO:0016481
|
negative regulation of transcription |
RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
1.57E-2 |
GO:0048547
|
gut morphogenesis |
BCL2,ACVR2B,GATA4, |
1.82E-2 |
GO:0048754
|
branching morphogenesis of a tube |
EDNRA,BCL2,VEGFA,FLT1, |
1.87E-2 |
GO:0045893
|
positive regulation of transcription, DNA-dependent |
ILF3,VEGFA,TCF7L1,EP300,NTF3,ZFPM2,GATA4,ZEB1, |
1.95E-2 |
GO:0051254
|
positive regulation of RNA metabolic process |
ILF3,VEGFA,TCF7L1,EP300,NTF3,ZFPM2,GATA4,ZEB1, |
2.05E-2 |
GO:0045892
|
negative regulation of transcription, DNA-dependent |
RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB1, |
2.11E-2 |
GO:0051253
|
negative regulation of RNA metabolic process |
RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB1, |
2.29E-2 |
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter |
VEGFA,TCF7L1,EP300,NTF3,ZFPM2,GATA4,ZEB1, |
2.59E-2 |
GO:0010629
|
negative regulation of gene expression |
RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
2.67E-2 |
GO:0001763
|
morphogenesis of a branching structure |
EDNRA,BCL2,VEGFA,FLT1, |
2.71E-2 |
GO:0016310
|
phosphorylation |
ATP6,BCL2,ACVR2B,SHC1,FLT1,IKBKB,LPAR1,NTRK2,TGFBR1,TBK1, |
2.73E-2 |
GO:0001569
|
patterning of blood vessels |
EDNRA,VEGFA,FLT1, |
2.79E-2 |
GO:0055123
|
digestive system development |
BCL2,ACVR2B,GATA4, |
2.79E-2 |
GO:0001702
|
gastrulation with mouth forming second |
RNF2,ACVR2B,GATA4, |
2.79E-2 |
GO:0048546
|
digestive tract morphogenesis |
BCL2,ACVR2B,GATA4, |
2.79E-2 |
GO:0006468
|
protein amino acid phosphorylation |
BCL2,ACVR2B,SHC1,FLT1,IKBKB,LPAR1,NTRK2,TGFBR1,TBK1, |
3.25E-2 |
GO:0010740
|
positive regulation of protein kinase cascade |
RHOA,FLNA,LPAR1,TGFBR1,TBK1, |
3.56E-2 |
GO:0051094
|
positive regulation of developmental process |
BCL2,JAG1,ACVR2B,RHOA,NTF3,GATA4, |
3.83E-2 |
GO:0010558
|
negative regulation of macromolecule biosynthetic process |
RNF2,ILF3,TCF7L1,KLF11,UBE2I,ZFPM2,ZEB2,ZEB1, |
4.20E-2 |
GO:0007160
|
cell-matrix adhesion |
FBLN5,BCL2,RHOA,FN1, |
4.56E-2 |
GO:0042490
|
mechanoreceptor differentiation |
JAG1,NTF3,NTRK2, |
5.30E-2 |
GO:0032388
|
positive regulation of intracellular transport |
RHOA,FLNA,TGFBR1, |
5.66E-2 |
GO:0010605
|
negative regulation of macromolecule metabolic process |
RNF2,ILF3,TCF7L1,KLF11,FLNA,UBE2I,ZFPM2,ZEB2,ZEB1, |
5.79E-2 |
GO:0043123
|
positive regulation of I-kappaB kinase/NF-kappaB cascade |
RHOA,FLNA,LPAR1,TBK1, |
5.80E-2 |
GO:0030182
|
neuron differentiation |
BCL2,JAG1,TUBB3,VEGFA,NTF3,NTRK2,TGFBR1, |
5.84E-2 |
GO:0051270
|
regulation of cell motion |
BCL2,JAG1,VEGFA,FLT1,TGFBR1, |
5.94E-2 |
GO:0031589
|
cell-substrate adhesion |
FBLN5,BCL2,RHOA,FN1, |
5.96E-2 |
GO:0051272
|
positive regulation of cell motion |
BCL2,VEGFA,FLT1,TGFBR1, |
5.96E-2 |
GO:0007242
|
intracellular signaling cascade |
KLF9,EDNRA,TUBB3,RHOA,SHC1,FLT1,FLNA,IKBKB,LPAR1,TGFBR1,TBK1,RIN2, |
6.23E-2 |
GO:0007166
|
cell surface receptor linked signal transduction |
ERBB2IP,ACVR2B,TCF7L1,SHC1,FLNA,FLT1,LPAR1,EDNRA,JAG1,TUBB3,VEGFA,BRD7,TGFBR1,NTRK2,PTPRD, |
7.24E-2 |
GO:0006916
|
anti-apoptosis |
BCL2,VEGFA,IKBKB,XIAP,TGFBR1, |
7.46E-2 |
GO:0007565
|
female pregnancy |
KLF9,BCL2,FLT1,TGFBR1, |
8.20E-2 |
GO:0048705
|
skeletal system morphogenesis |
ACVR2B,HOXB5,TGFBR1,ZEB1, |
8.62E-2 |
GO:0032147
|
activation of protein kinase activity |
EDNRA,ACVR2B,FLT1,TGFBR1, |
9.04E-2 |
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