ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-137

MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG
MI0000454	MIPF0000106	GGUCCUCUGACUCUCUUCGGUGACGGGUAUUCUUGGGUGGAUAAUACGGAUUACGUUGUUAUUGCUUAAGAAUACGCGUAGUCGAGGAGAGUACCAGCGGCA	MIMAT0000429 hsa-miR-137	UUAUUGCUUAAGAAUACGCGUAG

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

CSE1L,ZNF804A,CDC42,MITF,CDK6,BNIP3L,CXADR,MIB1,BCL2,YBX1,FMNL2,E2F6,ESRRA,CTBP1,KDM1A
more » CSE1L,ZNF804A,CDC42,MITF,CDK6,BNIP3L,CXADR,MIB1,BCL2,YBX1,FMNL2,E2F6,ESRRA,CTBP1,KDM1A,PTGS2,EZH2,NCOA2,FUNDC1,PXN

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05200	Pathways in cancer	CTBP1,CDK6,BCL2,MITF,PTGS2,CDC42,	2.04E-5
hsa04370	VEGF signaling pathway	PTGS2,PXN,CDC42,	4.29E-2
hsa05222	Small cell lung cancer	CDK6,BCL2,PTGS2,	5.36E-2
hsa04510	Focal adhesion	BCL2,PXN,CDC42,	2.86E-1
hsa05218	Melanoma	CDK6,MITF,	9.37E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0042127	regulation of cell proliferation	CTBP1,CDK6,CXADR,BCL2,MITF,PTGS2,ESRRA,	3.85E-4
GO:0010629	negative regulation of gene expression	NCOA2,CTBP1,E2F6,KDM1A,BNIP3L,KDM5B,	4.02E-4
GO:0045892	negative regulation of transcription, DNA-dependent	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	1.07E-2
GO:0006355	regulation of transcription, DNA-dependent	EZH2,NCOA2,CTBP1,MITF,E2F6,KDM1A,ESRRA,KDM5B,YBX1,	1.10E-2
GO:0008285	negative regulation of cell proliferation	CTBP1,CDK6,CXADR,BCL2,PTGS2,	1.13E-2

GO:0051253	negative regulation of RNA metabolic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	1.14E-2
GO:0051252	regulation of RNA metabolic process	EZH2,NCOA2,CTBP1,MITF,E2F6,KDM1A,ESRRA,KDM5B,YBX1,	1.28E-2
GO:0006357	regulation of transcription from RNA polymerase II promoter	NCOA2,CTBP1,MITF,E2F6,KDM1A,ESRRA,	2.10E-2
GO:0010605	negative regulation of macromolecule metabolic process	NCOA2,CTBP1,E2F6,KDM1A,BNIP3L,KDM5B,	2.19E-2
GO:0034330	cell junction organization	CXADR,BCL2,CDC42,	2.55E-2
GO:0016481	negative regulation of transcription	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	2.74E-2
GO:0045637	regulation of myeloid cell differentiation	CDK6,MITF,ESRRA,	3.82E-2
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	4.06E-2
GO:0051172	negative regulation of nitrogen compound metabolic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	4.26E-2
GO:0030278	regulation of ossification	CDK6,BCL2,ESRRA,	4.72E-2
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	NCOA2,CTBP1,E2F6,KDM1A,	4.92E-2
GO:0010558	negative regulation of macromolecule biosynthetic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	5.14E-2
GO:0031327	negative regulation of cellular biosynthetic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	5.62E-2
GO:0009890	negative regulation of biosynthetic process	NCOA2,CTBP1,E2F6,KDM1A,KDM5B,	6.06E-2
GO:0051329	interphase of mitotic cell cycle	CDK6,BCL2,E2F6,	8.11E-2
GO:0051325	interphase	CDK6,BCL2,E2F6,	8.57E-2
GO:0051726	regulation of cell cycle	CDK6,BCL2,PTGS2,CDC42,	9.01E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value