The Detail Information for This Interaction


  • Detail
  • Binding
  • Network
Detail:
ncRNA Symmbol:miR-125a
ncRNA Category:miRNA
Interaction Gene Symbol: Mcl1
Death Pathway:apoptosis
Expression Direction of ncRNA:down
Species:Rattus norvegicus
Tissue:intestinal epithelium cells
PMID: 22418008
Detail Description:

Upregulation of miR-125a suppresses the prosurvival protein mcl1, producing the increase in apoptosis known to accompany the proliferative changes characteristic of intestinal adaptation. 

Select the ncRNA symbol and transcript of gene
Mature of miR-125a    Transcript of Mcl1    
Visualization:
Select the center nodes: First Node Second Node Both the Nodes
Select the Level of Neighbour: First Neighbour Second Neighbour

The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node, the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node, the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node. Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.


The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.