Detail: | |
ncRNA Symmbol: | miR-16 |
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ncRNA Category: | miRNA |
Interaction Gene Symbol: | Bag5 |
Death Pathway: | autophagy |
Expression Direction of ncRNA: | |
Species: | Mus musculus |
Tissue: | neuroectodermal tissues |
PMID: | 21770019 |
Detail Description: | MicroRNAs miR-16-1 (miR-16) and miR-15b have been reported to function as tumor suppressors and negative regulators of cell growth. A number of studies support the existence of a complex interplay between autophagy, cell growth and apoptosis required for mammalian neural tube development. Bcl2 and the Bcl2-like anti-apoptotic proteins BCL2-associated athanogene 5 (Bag5) and BCL2-like 2 (Blc2l2) are targets of miR-16 and miR-15a (miRDB). |
The 'First Node' or 'Second Node' option represents the sub-network of interacting entry with the first or second interaction node,
the 'Both the Nodes' option represents the sub-network of interacting entry with both of interaction nodes.
The 'First Neighbour' represents the sub-network of direct interacting with the center node,
the 'Second Neighbour' represents the sub-network of direct or second step interacting with the center node.
Interaction sub-network based on the two nodes of this interaction may help the researchers represents all interacting partners immediately.
The Detail page: representing the detail information for RNA-RNA/RNA-Protein interaction;
The Binding page: representing the predicted binding sites and/or constants.
The Network page: representing the interaction sub-network of interacting RNA/Protein.