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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001524
Name CTNNA1
Gene ID 1495
Location Coordinate(Strand) 5:138610967-138935034(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay and in vivo assay (Mouse)
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Cell proliferation assay
High-throughput method /
Tissue/Cell Colorectal tumor sample;SW480 cell;SW620 cell
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR and luciferase assay in SW480 cell and SW620 cell, which can promote tumor growth in human cancer by sponging miR-141,acting as a decoy for CTNNA1-targeting microRNAs

Orthologues:

  
Chimpanzee ENSPTRG00000017291  
Mouse ENSMUSG00000037815  
Drosophila FBgn0010215  
Zebrafish ENSDARG00000102441  

References:

  
PMID 27487124
Description Our findings add a new regulatory circuit via competing endogenous RNA (ceRNA) cross-talk between pseudogene CTNNAP1 and its cognate gene CTNNA1.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
Nucleus RLID00038472 Link to RNALocate
chromatin RLID00060358 Link to RNALocate
cytosol RLID00060359 Link to RNALocate
cytosol RLID00060360 Link to RNALocate
membrane RLID00060361 Link to RNALocate
nucleolus RLID00060362 Link to RNALocate
nucleoplasm RLID00060363 Link to RNALocate
nucleus RLID00060364 Link to RNALocate
nucleus RLID00060365 Link to RNALocate
exosome RLID00060366 Link to RNALocate
Nucleus RLID00003857 Link to RNALocate
Ribosome RLID00003858 Link to RNALocate
Cytosol RLID00003859 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Macular dystrophy, patterned, 2 OMIM:608970 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).