Basic information:

Untranslated mRNA: Scaffold mRNA

Related IDs	cncRNA ID	CNC_M_001606
	Name	H2BC21
	Gene ID	8349
Location	Coordinate(Strand)	1:149884459-149886652(-)
Locus Sequence
Organism	Homo sapiens

Evidence support:

  

In vivo/vitro assay	In vitro assay
Low-throughput method	Transfection assay;Immunofluorescence;RNA fish
High-throughput method	/
Tissue/Cell	Hela cell
Description of experimental evidence	The mRNA was detected by transfection assay, immunofluorescence and RNA fish in Hela cell, which can function as a scaffold in the formation of major nuclear bodies.

Orthologues:

  

Chimpanzee	ENSPTRG00000050454
Mouse	/
Drosophila	/
Zebrafish	/

References:

  

PMID	21240286
Description	Here we show that RNA can function as a structural element and a nucleator of nuclear bodies. We find that several types of coding and noncoding RNAs are sufficient to de novo assemble, and are physiologically enriched in, histone locus bodies (with associated Cajal bodies), nuclear speckles, paraspeckles and nuclear stress bodies.