Go Back

Detail Information


Basic information:


Translated ncRNA: circRNA

Related IDs cncRNA ID CNC_N_000002
Name circGprc5a
Gene ID ENSG00000013588
Location Coordinate(Strand) 12:12891559-12917937(+)
Locus Sequence
Organism Homo sapiens

Peptide information:

  
Peptide FDTKPMNLCGR
Peptide length 11

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Western blotting
High-throughput method /
Tissue/Cell Bladder cancer stem cell
Description of experimental evidence The peptide was detected by western blotting in Bladder cancer stem cell, which can promote bladder oncogenesis and metastasis, and the function of peptide was validated on Bladder cancer stem cell.

Orthologues:

  
Chimpanzee ENSPTRG00000004710  
Mouse ENSMUSG00000046733  
Drosophila /
Zebrafish ENSDARG00000099947  

References:

  
PMID 30497053
Description CircGpr5a has peptide-coding potential and functions through a peptide-dependent manner. circGprc5a-peptide binds to Gprc5a, a surface protein highly expressed in bladder cancer stem cell.

Related Diseases:

  
Disease MNDR ID Link to MNDR
Bladder cancer MNDR-E-CIRC-1331 Link to MNDR