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Detail Information
Basic Information:
VIRBase ID:
HVID00009258
Virus:
SARS-CoV-2 (NC_045512.2)
Host:
Homo sapiens
Confidence Score:
0.2202
Interaction Type:
Host-Virus interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-miR-122-5p
ORF8
miRBase
Accession/Entrez ID
MIMAT0000421
43740577
Organism
Homo sapiens
SARS-CoV-2 (NC_045512.2)
Category
miRNA
mRNA
Alias
-
GU280_gp09
ncRNA SNP information:
Resource
Symbol
SNP ID
SNP Position
Ref/Alt
miRNASNP-v3
hsa-miR-122-5p
rs1258166649
chr18:58451088
T/C
rs1426570658
chr18:58451093
T/A
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
hsa-miR-122-5p
Cytoplasm
Huh-7 cells|Sorafenib-resistant Huh-7 cells (Huh-7-DR)
29253196
Cytoplasm
Huh-7 cells
29486652
Cytoplasm
Nasopharyngeal carcinoma cells
20498841
Endoplasmic reticulum
Huh-7 cells
26304123
Exosome
Breast cancer cell lines (MCF10A|MDA-MB-231)
25621950
Exosome
B cell line (Raji)
21505438
Exosome
Brain tissue
23382797
Exosome
Plasma
23663360
Exosome
Human mast cell line (HMC-1)
24009880
Exosome
B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells
25242326
Exosome
Blood|Chronic lymphocytic leukemia cells
-
Microvesicle
Plasma
23077538
Microvesicle
Seminal plasma
23539611
Microvesicle
Blood|Fibroblasts|Mesenchymal stem cells|Urine
-
Mitochondrion
Cell line (HEK-293|HeLa)
22984580
Nucleus
Adjacent noncancerous tissue|HCC tissue|Huh-7 cells|Sorafenib-resistant Huh-7 cells (Huh-7-DR)
29253196
Nucleus
Nasopharyngeal carcinoma cells
20498841
Polysome
Human cervical cancer cell line (HeLa)
25609084
Interaction Network
(The top 100 interactions)
:
Interactor1: hsa-miR-122-5p
Interactor2: ORF8
Evidence Support:
Prediction-Evidence
miRanda//miRTarP
Support Database
ViRBase
References:
PMID
33801496
Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
None
Interactor2 expression
None
Description
Additionally, if targets are selected by both tools in at least two strains of SARS-CoV-2, we only considered them as potential targets of miRNA on SARS-CoV-2 (Table S2). In Table 1, we present the list of miRNAs meeting all these criteria.
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