Basic Information
| RNALocate ID: | RLID:11001712 |
| RNA Symbol: | hsa-miR-122-5p |
| Localization: | Microvesicle |
RNA Information
| RNA Name: | hsa-miR-122 |
| RNA ID: | miRBase:MIMAT0000421 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 23539611 |
| Tissue/Cell Line: | Seminal plasma |
| Method: | Microarray |
| Description: | In order to assess the reversibility of post-vasectomy miRNA sequelae, we investigated whether SMV miRNAs altered by vasectomy could be retrieved in SMVs from normospermic vasovasostomized donors. miRNA microarray profiling performed on SMVs from normal, vasectomized and vasovasostomized donors identified 313 miRNAs whose intensity was above the threshold of detection. Among these miRNAs, 293 were detected in samples from normal donors, 275 in vasectomized donors and 298 in vasovasostomized donors (Fig. 3, Supplementary data, Table SIV). Data are collected from Table S4. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01001744 | Cytoplasm | Huh-7 cells|Sorafenib-resistant Huh-7 cells (Huh-7-DR) | 29253196 |
| RLID:01001745 | Cytoplasm | Huh-7 cells | 29486652 |
| RLID:01001746 | Cytoplasm | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001747 | Endoplasmic reticulum | Huh-7 cells | 26304123 |
| RLID:01001748 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01001749 | Nucleus | Adjacent noncancerous tissue|HCC tissue|Huh-7 cells|Sorafenib-resistant Huh-7 cells (Huh-7-DR) | 29253196 |
| RLID:01001750 | Nucleus | Nasopharyngeal carcinoma cells | 20498841 |
| RLID:01001751 | Polysome | Human cervical cancer cell line (HeLa) | 25609084 |
| RLID:11001705 | Exosome | Breast cancer cell lines (MCF10A|MDA-MB-231) | 25621950 |
| RLID:11001706 | Exosome | B cell line (Raji) | 21505438 |
| RLID:11001707 | Exosome | Brain tissue | 23382797 |
| RLID:11001708 | Exosome | Plasma | 23663360 |
| RLID:11001709 | Exosome | Human mast cell line (HMC-1) | 24009880 |
| RLID:11001710 | Exosome | B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells | 25242326 |
| RLID:11001711 | Microvesicle | Plasma | 23077538 |
| RLID-D:11000074 | Exosome | Blood|Chronic lymphocytic leukemia cells | |
| RLID-D:11000349 | Microvesicle | Blood|Fibroblasts|Mesenchymal stem cells|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-122-5p | Disease of metabolism | MNDR-E-MI-05314 |
| MNDR | hsa-miR-122-5p | Oral squamous cell carcinoma | MNDR-E-MI-05315 |
| MNDR | hsa-miR-122-5p | Lymphoma | MNDR-E-MI-05316 |
| MNDR | hsa-miR-122-5p | Cutaneous t cell lymphoma | MNDR-E-MI-05317 |
| MNDR | hsa-miR-122-5p | Estrogen-receptor positive breast cancer | MNDR-E-MI-05318 |
| MNDR | hsa-miR-122-5p | Estrogen-receptor negative breast cancer | MNDR-E-MI-05319 |
| MNDR | hsa-miR-122-5p | Progesterone-receptor positive breast cancer | MNDR-E-MI-05320 |
| MNDR | hsa-miR-122-5p | Progesterone-receptor negative breast cancer | MNDR-E-MI-05321 |
| MNDR | hsa-miR-122-5p | Her2-receptor positive breast cancer | MNDR-E-MI-05322 |
| MNDR | hsa-miR-122-5p | Breast cancer luminal a | MNDR-E-MI-05323 |
| MNDR | hsa-miR-122-5p | Precursor cell lymphoblastic leukemia-lymphoma | MNDR-E-MI-05324 |
| MNDR | hsa-miR-122-5p | Prostate cancer | MNDR-E-MI-05325 |
| MNDR | hsa-miR-122-5p | Gastric cancer | MNDR-E-MI-05326 |
| MNDR | hsa-miR-122-5p | Alzheimer disease | MNDR-E-MI-05327 |
| MNDR | hsa-miR-122-5p | Head and neck cancer | MNDR-E-MI-05328 |
| MNDR | hsa-miR-122-5p | Primary biliary cirrhosis | MNDR-E-MI-05329 |
| MNDR | hsa-miR-122-5p | Huntington disease | MNDR-E-MI-05330 |
| MNDR | hsa-miR-122-5p | Cardiovascular disease | MNDR-E-MI-05331 |
| MNDR | hsa-miR-122-5p | Moyamoya disease | MNDR-E-MI-05332 |
| MNDR | hsa-miR-122-5p | Biliary atresia | MNDR-E-MI-05333 |
| MNDR | hsa-miR-122-5p | Parkinson disease | MNDR-E-MI-05334 |
| MNDR | hsa-miR-122-5p | Basal-like breast cancer | MNDR-E-MI-05335 |
| MNDR | hsa-miR-122-5p | Pituitary neoplasms | MNDR-E-MI-05336 |
| MNDR | hsa-miR-122-5p | Pancreatic cancer | MNDR-E-MI-05337 |
| MNDR | hsa-miR-122-5p | HCV | MNDR-E-MI-05338 |
| MNDR | hsa-miR-122-5p | Melanoma | MNDR-E-MI-05339 |
| MNDR | hsa-miR-122-5p | Hepatitis B | MNDR-E-MI-05340 |
| MNDR | hsa-miR-122-5p | Colon cancer | MNDR-E-MI-05341 |
| MNDR | hsa-miR-122-5p | Ischemic attack transient | MNDR-E-MI-05342 |
| MNDR | hsa-miR-122-5p | Familial ovarian cancer | MNDR-E-MI-05343 |
| MNDR | hsa-miR-122-5p | Kidney cancer | MNDR-E-MI-05344 |
| MNDR | hsa-miR-122-5p | Glioblastoma | MNDR-E-MI-05345 |
| MNDR | hsa-miR-122-5p | Glioma | MNDR-E-MI-05346 |
| MNDR | hsa-miR-122-5p | Chronic obstructive pulmonary disease | MNDR-E-MI-05347 |
| MNDR | hsa-miR-122-5p | Gastrointestinal cancer | MNDR-E-MI-05348 |
| MNDR | hsa-miR-122-5p | Amyotrophic lateral sclerosis | MNDR-E-MI-05349 |
| MNDR | hsa-miR-122-5p | Osteosarcoma | MNDR-E-MI-05350 |
| MNDR | hsa-miR-122-5p | Coronary artery disease | MNDR-E-MI-05351 |
| MNDR | hsa-miR-122-5p | Pancreatic ductal adenocarcinoma | MNDR-E-MI-05352 |
| MNDR | hsa-miR-122-5p | Liver cancer | MNDR-E-MI-05353 |
| MNDR | hsa-miR-122-5p | Uterine cancer | MNDR-E-MI-05354 |
| MNDR | hsa-miR-122-5p | Cervical squamous cell carcinoma | MNDR-E-MI-05355 |
| MNDR | hsa-miR-122-5p | Pituitary adenoma | MNDR-E-MI-05356 |
| MNDR | hsa-miR-122-5p | Lung squamous cell carcinoma | MNDR-E-MI-05357 |
| MNDR | hsa-miR-122-5p | Carcinoma lung non-small-cell | MNDR-E-MI-05358 |
| MNDR | hsa-miR-122-5p | Lung adenocarcinoma | MNDR-E-MI-05359 |
| MNDR | hsa-miR-122-5p | Pancreatic adenocarcinoma | MNDR-E-MI-05360 |
| MNDR | hsa-miR-122-5p | Myasthenia gravis autoimmune experimental | MNDR-E-MI-05361 |
| MNDR | hsa-miR-122-5p | Kidney renal clear cell carcinoma | MNDR-E-MI-05362 |
| MNDR | hsa-miR-122-5p | Clear cell renal cell carcinoma | MNDR-E-MI-05363 |
| MNDR | hsa-miR-122-5p | Biliary tract cancer | MNDR-E-MI-05364 |
| MNDR | hsa-miR-122-5p | Neoplasms of the small intestine | MNDR-E-MI-05365 |
| MNDR | hsa-miR-122-5p | Intrahepatic cholangiocarcinoma | MNDR-E-MI-05366 |
| MNDR | hsa-miR-122-5p | Cholangiocarcinoma | MNDR-E-MI-05367 |
| MNDR | hsa-miR-122-5p | Esophageal cancer | MNDR-E-MI-05368 |
| MNDR | hsa-miR-122-5p | Liver cirrhosis | MNDR-E-MI-05369 |
| MNDR | hsa-miR-122-5p | Synovial sarcoma | MNDR-E-MI-05370 |
| MNDR | hsa-miR-122-5p | Head and neck squamous cell carcinoma | MNDR-E-MI-05371 |
| MNDR | hsa-miR-122-5p | Early hepatocellular carcinoma | MNDR-E-MI-05372 |
| MNDR | hsa-miR-122-5p | Familiar ovarian carcinoma | MNDR-E-MI-05373 |
| MNDR | hsa-miR-122-5p | B-cell lymphoma | MNDR-E-MI-05374 |
| MNDR | hsa-miR-122-5p | Rheumatoid arthritis | MNDR-E-MI-05375 |
| MNDR | hsa-miR-122-5p | Malignant pleural mesothelioma | MNDR-E-MI-05376 |
| MNDR | hsa-miR-122-5p | Retinoblastoma | MNDR-E-MI-05377 |
| MNDR | hsa-miR-122-5p | Osteoarthritis | MNDR-E-MI-05378 |
| MNDR | hsa-miR-122-5p | Knee osteoarthritis | MNDR-E-MI-05379 |
| MNDR | hsa-miR-122-5p | Psoriasis | MNDR-E-MI-05380 |
| MNDR | hsa-miR-122-5p | Colorectal cancer | MNDR-E-MI-05381 |
| MNDR | hsa-miR-122-5p | Nasopharynx carcinoma | MNDR-E-MI-05382 |
| MNDR | hsa-miR-122-5p | Type 2 diabetes mellitus | MNDR-E-MI-05383 |
| MNDR | hsa-miR-122-5p | Acute myocardial infarction | MNDR-E-MI-05384 |
| MNDR | hsa-miR-122-5p | Fatty liver disease | MNDR-E-MI-05385 |
| MNDR | hsa-miR-122-5p | Multiple myeloma | MNDR-E-MI-05386 |
| MNDR | hsa-miR-122-5p | Acute lymphocytic leukemia | MNDR-E-MI-05387 |
| MNDR | hsa-miR-122-5p | Infection | MNDR-E-MI-05388 |
| MNDR | hsa-miR-122-5p | Nasopharyngeal cancer | MNDR-E-MI-05389 |
| MNDR | hsa-miR-122-5p | Aids dementia complex | MNDR-E-MI-05390 |
| MNDR | hsa-miR-122-5p | Liver failure | MNDR-E-MI-05391 |
| MNDR | hsa-miR-122-5p | Acute liver failure | MNDR-E-MI-05392 |
| MNDR | hsa-miR-122-5p | Cerebral hemorrhage traumatic | MNDR-E-MI-05393 |
| MNDR | hsa-miR-122-5p | Intracranial hemorrhage hypertensive | MNDR-E-MI-05394 |
| MNDR | hsa-miR-122-5p | Stroke lacunar | MNDR-E-MI-05395 |
| MNDR | hsa-miR-122-5p | Non-alcoholic fatty liver disease | MNDR-E-MI-05396 |
| MNDR | hsa-miR-122-5p | Breast cancer her3+ negative | MNDR-E-MI-05397 |
| MNDR | hsa-miR-122-5p | High grade dysplastic nodule | MNDR-E-MI-05398 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | AACS | Homo sapiens | RR00020644 |
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