Basic Information:
VIRBase ID: HVID00000041
Virus: Borna disease virus (BDV)
Host: Homo sapiens
Confidence Score: 0.9026
Interaction Type: Host-Virus interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-miR-122-5p
N
miRBase Accession/Entrez ID
MIMAT0000421
26799168
Organism
Homo sapiens
Borna disease virus (BDV)
Category
miRNA
mRNA
Alias
-
BDVgp1
ncRNA SNP information:
Resource
Symbol
SNP ID
SNP Position
Ref/Alt
miRNASNP-v3
hsa-miR-122-5p
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
hsa-miR-122-5p
Interaction Network (The top 100 interactions) :
Interactor1: hsa-miR-122-5p
Interactor2: N
Evidence Support:
Strong-Evidence
PCR//Western blot
Prediction-Evidence
RNAHybrid
Support Database
ViRBase
References:
PMID
20561966
Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
BDV cells//OL cells
Interactor2 expression
None
Description
The results showed that miR-122 could bind specifically to the 5' and 3' end of target mRNAs of BDV encoding for N and P proteins, both on two positions (Fig. 1B). These results indicated that BDV persistent infection and BDV P and N proteins were able to suppress the expression of miR-122.