Detail Information

Basic Information:


  VIRBase ID:  

HHID00105291

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-411-5p:           TNF:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-411-5p TNF
miRBase
Accession/Entrez ID		 MIMAT0003329 7124
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DIF//TNF-alpha//TNFA//TNFSF2//TNLG1F

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-411-5p
rs1361369657 chr14:101023352    T/TA
rs536735599 chr14:101023348    C/T
rs567582018 chr14:101023340    T/C
rs751955845 chr14:101023355    C/T
rs757784113 chr14:101023356    G/A
rs758726179 chr14:101023349    G/A
rs764544909 chr14:101023354    G/A
rs780559779 chr14:101023359    C/T
rs1157612570 chr14:101023345    G/C
rs1165649618 chr14:101023341    A/G
rs753033941 chr14:101023343    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TNF
chr6:31543363-31543364(+) m6A 5'UTR       -
chr6:31543373-31543374(+) m6A 5'UTR       -
chr6:31543403-31543404(+) m6A 5'UTR       -
chr6:31543416-31543417(+) m6A 5'UTR       -
chr6:31543513-31543514(+) m6A 5'UTR       -
chr6:31545104-31545105(+) m6A CDS       26404942
chr6:31545152-31545153(+) m6A CDS       26404942
chr6:31545323-31545324(+) m6A 3'UTR       26404942
chr6:31545382-31545383(+) m6A 3'UTR       26404942
chr6:31545434-31545435(+) m6A 3'UTR       26404942
chr6:31545447-31545448(+) m6A 3'UTR       26404942
chr6:31545462-31545463(+) m6A 3'UTR       26404942
chr6:31545476-31545477(+) m6A 3'UTR       26404942
chr6:31545537-31545538(+) m6A 3'UTR       26404942
chr6:31545552-31545553(+) m6A 3'UTR       26404942
chr6:31545599-31545600(+) m6A 3'UTR       26404942
chr6:31545636-31545637(+) m6A 3'UTR       26404942
chr6:31545646-31545647(+) m6A 3'UTR       26404942
chr6:31545673-31545674(+) m6A 3'UTR       26404942
chr6:31545706-31545707(+) m6A 3'UTR       26404942
chr6:31545717-31545718(+) m6A 3'UTR       26404942
chr6:31545833-31545834(+) m6A 3'UTR       26404942
chr6:31545851-31545852(+) m6A 3'UTR       26404942
chr6:31545879-31545880(+) m6A 3'UTR       26404942
chr6:31545906-31545907(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-411-5p
Exosome Serum     18589210
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Blood|B lymphoblastoid cells|Endothelial cells|Mast cells     -
Microvesicle Follicular fluid     23666971
Microvesicle Blood|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
TNF
Exosome Blood     -
Polysome HeLa cells     26000482

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-411-5p
Interactor2: TNF

Evidence Support:


Prediction-Evidence microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database ViRBase

References:


PMID 33428154 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.

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