Basic Information
| RNALocate ID: | RLID:00017827 |
| RNA Symbol: | TNF |
| Localization: | Polysome |
RNA Information
| RNA Name: | Tnf |
| RNA ID: | NCBI:7124|Ensembl:ENSG00000232810 |
| RNA Category: | mRNA |
| Species: | Homo sapiens |
| Alias: | DIF|TNF-alpha|TNFA|TNFSF2|TNLG1F |
Localization Information
| PubMed ID: | 26000482 |
| Tissue/Cell Line: | HeLa cells |
| Method: | qRT-PCR |
|
Quantification of RNAs of non-polysome and polysome fractions. The lysates from HeLa cells transfected with indicated siRNA and stimulated with IL-1β were fractionated by sucrose gradient (F), and RNAs from the fractions were analyzed by RT-qPCR for the expression of indicated mRNAs (G and H). Originally published in Cell. Mino T, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
| Description: | Because Il6, Tnf, and Ptgs2 mRNAs present in polysomal fractions rapidly increased in response to IL-1 b stimulation in HeLa cells and then decreased at later time points ( Figures 3H and S7 C), we hypothesized that the contribution of translation-dependent decay by Reg1 changes in the time course of BMM activation. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID-D:10013757 | Exosome | Blood |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | MEG3 | Homo sapiens | RR00912391 |
TOP