Detail Information

Basic Information:


  VIRBase ID:  

HHID00105024

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      SENCR:           IL6:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol SENCR IL6
miRBase
Accession/Entrez ID		 100507392 3569
Organism Homo sapiens Homo sapiens
Category lncRNA mRNA
Alias FLI1-AS1//lncRNA9 BSF-2//BSF2//CDF//HGF//HSF//IFN-beta-2//IFNB2//IL-6

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt PMID
LincSNP 3.0 SENCR
rs695113 chr11:128692203 A/G         22182935

RNA Editing:


Resource Symbol Editing Position
Lncediting SENCR
    chr11: 128565912
    chr11: 128565905
    chr11: 128565904
    chr11: 128565872
    chr11: 128565857
    chr11: 128565820
Resource Symbol Editing Position Change Genetic Region
RADAR IL6
chr7:22770700(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SENCR
chr11:128561888-128561889(-) m6A exon       -
chr11:128561932-128561933(-) m6A exon       -
chr11:128561944-128561945(-) m6A exon       -
chr11:128561993-128561994(-) m6A exon       -
chr11:128562664-128562665(-) m6A exon       -
chr11:128562676-128562677(-) m6A exon       -
chr11:128562703-128562704(-) m6A exon       -
chr11:128562712-128562713(-) m6A exon       -
chr11:128562727-128562728(-) m6A exon       -
chr11:128562802-128562803(-) m6A exon       27371828
chr11:128562854-128562855(-) m6A exon       24981863//27371828
chr11:128562875-128562876(-) m6A exon       24981863//27371828
chr11:128562892-128562893(-) m6A exon       24981863//27371828
chr11:128562898-128562899(-) m6A exon       27371828
chr11:128562944-128562945(-) m6A exon       27371828
chr11:128562975-128562976(-) m6A exon       -
chr11:128563033-128563034(-) m6A exon       -
chr11:128563052-128563053(-) m6A exon       -
chr11:128563184-128563185(-) m6A exon       -
IL6
chr7:22766885-22766886(+) m6A 5'UTR//CDS//exon       -
chr7:22766928-22766929(+) m6A exon//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate SENCR
Exosome Blood     -
IL6
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Serum     -
Nucleus HeLa-S3 cells     -
Polysome HeLa cells     26000482

Interaction Network (The top 100 interactions):


Interactor1: SENCR
Interactor2: IL6

Evidence Support:


Prediction-Evidence LncRNA2Target
Support Database ViRBase

References:


PMID 33520952 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified a total of 24 cytokine-lncRNA relationships using LncRNA2Target (Table 2). The most significant lncRNAs associated with COVID-19 cytokine storm cytokines, accompanied by lncRNA target prediction analysis using average ndG values.

Starting a new search, please wait ...