Basic Information
| RNALocate ID: | RLID:00011061 |
| RNA Symbol: | IL6 |
| Localization: | Polysome |
RNA Information
| RNA Name: | IL6 |
| RNA ID: | NCBI:3569|Ensembl:ENSG00000136244 |
| RNA Category: | mRNA |
| Species: | Homo sapiens |
| Alias: | BSF-2|BSF2|CDF|HGF|HSF|IFN-beta-2|IFNB2|IL-6 |
Localization Information
| PubMed ID: | 26000482 |
| Tissue/Cell Line: | HeLa cells |
| Method: | qRT-PCR |
|
Quantification of RNAs of non-polysome and polysome fractions. The lysates from HeLa cells transfected with indicated siRNA and stimulated with IL-1β were fractionated by sucrose gradient (F), and RNAs from the fractions were analyzed by RT-qPCR for the expression of indicated mRNAs (G and H). Originally published in Cell. Mino T, et al, 2015. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
|
| Description: | Knockdown of Reg1 resulted in a large increase in IL6 and PTGS2 mRNA expression in the polysome fractions (fractions 7-12) compared with control cells, whereas the mRNA in non-polysome fractions (fractions 3-6) were comparable (Figure 3H). |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:00011060 | Endoplasmic reticulum | Human myelogenous leukemia cell line (K-562) | 21613539 |
| RLID-D:00035294 | Nucleus | HeLa-S3 cells | |
| RLID-D:10007495 | Exosome | Serum |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | IL7R | Homo sapiens | RR00749322 |
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