Detail Information

Basic Information:


  VIRBase ID:  

HHID00096532

  Virus:  

Human immunodeficiency virus (HIV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320a-5p:           CLK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320a-5p CLK1
miRBase
Accession/Entrez ID		 MIMAT0037311 1195
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CLK//CLK/STY//STY

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320a-5p
rs1178430716 chr8:22245014    C/A
rs1178430716 chr8:22245014    C/T
rs1222383224 chr8:22245020    A/C
rs1302873200 chr8:22245028    C/T
rs751837733 chr8:22245017    G/A
rs751837733 chr8:22245017    G/T
rs759553956 chr8:22245018    G/A
rs762775040 chr8:22245011    G/A
rs762775040 chr8:22245011    G/C
rs766581008 chr8:22245016    G/A
rs767640621 chr8:22245019    A/G
rs773034756 chr8:22245010    A/G
rs773281428 chr8:22245008    G/A
rs773281428 chr8:22245008    G/C
rs371890344 chr8:22245023    G/A
rs371890344 chr8:22245023    G/C
rs375622631 chr8:22245027    G/A
rs566154595 chr8:22245021    G/A
rs566154595 chr8:22245021    G/C
rs764559789 chr8:22245026    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CLK1
chr2:201720864(-) A-I      intronic
chr2:201720918(-) A-I      intronic
chr2:201720990(-) A-I      intronic
chr2:201721100(-) A-I      intronic
chr2:201718448(-) A-I      intronic
chr2:201721019(-) A-I      intronic
chr2:201718470(-) A-I      intronic
chr2:201721060(-) A-I      intronic
chr2:201721057(-) A-I      intronic
chr2:201721044(-) A-I      intronic
chr2:201720988(-) A-I      intronic
chr2:201720848(-) A-I      intronic
chr2:201720694(-) A-I      intronic
chr2:201720632(-) A-I      intronic
chr2:201720623(-) A-I      intronic
chr2:201720551(-) A-I      intronic
chr2:201720473(-) A-I      intronic
chr2:201720224(-) A-I      intronic
chr2:201721072(-) A-I      intronic
chr2:201720861(-) A-I      intronic
chr2:201720964(-) A-I      intronic
chr2:201721066(-) A-I      intronic
chr2:201720972(-) A-I      intronic
chr2:201720564(-) A-I      intronic
chr2:201720971(-) A-I      intronic
chr2:201720475(-) A-I      intronic
chr2:201719982(-) A-I      intronic
chr2:201720872(-) A-I      intronic
chr2:201720645(-) A-I      intronic
chr2:201720649(-) A-I      intronic
chr2:201720902(-) A-I      intronic
chr2:201720868(-) A-I      intronic
chr2:201720584(-) A-I      intronic
chr2:201720120(-) A-I      intronic
chr2:201720935(-) A-I      intronic
chr2:201720226(-) A-I      intronic
chr2:201719987(-) A-I      intronic
chr2:201720575(-) A-I      intronic
chr2:201720706(-) A-I      intronic
chr2:201720965(-) A-I      intronic
chr2:201720467(-) A-I      intronic
chr2:201721013(-) A-I      intronic
chr2:201719954(-) A-I      intronic
chr2:201718487(-) A-I      intronic
chr2:201720905(-) A-I      intronic
chr2:201720488(-) A-I      intronic
chr2:201721043(-) A-I      intronic
chr2:201720961(-) A-I      intronic
chr2:201720685(-) A-I      intronic
chr2:201720926(-) A-I      intronic
chr2:201720932(-) A-I      intronic
chr2:201720922(-) A-I      intronic
chr2:201720163(-) A-I      intronic
chr2:201720520(-) A-I      intronic
chr2:201721116(-) A-I      intronic
chr2:201720863(-) A-I      intronic
chr2:201720540(-) A-I      intronic
chr2:201721117(-) A-I      intronic
chr2:201720968(-) A-I      intronic
chr2:201728025(-) A-I      intronic
chr2:201720962(-) A-I      intronic
chr2:201720548(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CLK1
chr2:201720475(-) A-I intron -    21960545   //22327324
chr2:201721117(-) A-I intron -    21960545
chr2:201719987(-) A-G intron -    22484847
chr2:201720111(-) A-G intron -    22484847
chr2:201720475(-) A-G intron -    22484847
chr2:201720548(-) A-G intron -    22484847
chr2:201720645(-) A-G intron -    22484847
chr2:201720649(-) A-G intron -    22484847
chr2:201720685(-) A-G intron -    22484847
chr2:201720935(-) A-G intron -    22484847
chr2:201720958(-) A-G intron -    22484847
chr2:201720961(-) A-G intron -    22484847
chr2:201720962(-) A-G intron -    22484847
chr2:201720964(-) A-G intron -    22484847
chr2:201720971(-) A-G intron -    22484847
chr2:201720977(-) A-G intron -    22484847
chr2:201721035(-) A-G intron -    22484847
chr2:201721065(-) A-G intron -    22484847
chr2:201721066(-) A-G intron -    22484847
chr2:201721116(-) A-G intron -    22484847
chr2:201728306(-) G-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CLK1
chr2:201717737-201717738(-) m6A 3'UTR       27773535
chr2:201717786-201717787(-) m6A 3'UTR       27773535
chr2:201717861-201717862(-) m6A 3'UTR//exon       27773535
chr2:201717989-201717990(-) m6A 3'UTR//exon       26404942//27773535
chr2:201718015-201718016(-) m6A 3'UTR//exon       26404942//27773535
chr2:201722802-201722803(-) m6A 3'UTR//CDS//exon       27773535
chr2:201722876-201722877(-) m6A 5'UTR//intron       24981863//27773535
chr2:201724916-201724917(-) m6A CDS//exon//intron       24981863
chr2:201726002-201726003(-) m6A CDS//exon       24981863
chr2:201726054-201726055(-) m6A CDS//exon       24981863
chr2:201726075-201726076(-) m6A CDS//exon       24981863
chr2:201726089-201726090(-) m6A CDS//exon       24981863
chr2:201726095-201726096(-) m6A CDS//exon       24981863
chr2:201726216-201726217(-) m6A exon//intron       27773535
chr2:201726463-201726464(-) m6A CDS//exon//intron       24981863//28052920//27773535
chr2:201726566-201726567(-) m6A CDS//exon//intron       24209618//24981863//27773535
chr2:201726579-201726580(-) m6A CDS//exon//intron       24209618//24981863//27773535
chr2:201729264-201729265(-) m6A 5'UTR//intron       24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320a-5p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Human cervical cancer cell line (HeLa)     25760330
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     25135963
Exosome Human esophageal cancer cell line (EC9706)     25184951
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Cerebrospinal fluid     25420022
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Serum     24797360
Mitochondrion HEK-293 cells|HeLa cells     27396686
Mitochondrion HEK-293 cells|HeLa cells     27563705
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
CLK1
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320a-5p
Interactor2: CLK1

Evidence Support:


Weak-Evidence Small RNA sequencing
Prediction-Evidence miRNet
Support Database ViRBase

References:


PMID 33045840 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line PBMC cells Interactor2 expression Downregulation
Description FIG. 2.(B) upregulated miRNAs with their predicted downregulated gene targets.

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