Basic Information
| RNALocate ID: | RLID:11005223 |
| RNA Symbol: | hsa-miR-320a-5p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-miR-320a |
| RNA ID: | miRBase:MIMAT0037311 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 20976003 |
| Tissue/Cell Line: | Breast cancer cell line (MCF-7) |
| Method: | Microarray |
| Description: | Because of the suggested roles of extracellular miRNAs in signaling and diagnosis, we investigated whether the intracellular and extracellular miRNA composition are the same. To answer this question, we performed microRNA microarray analyses of MCF7 cellular (c) and extracellular (x) RNAs (Figure 2A), and found that about 66% of the released miRNAs are at an abundance that closely reflects the cellular miRNA abundance (Figures 2B and 2C). This finding is in agreement with a model wherein most, but not all miRNAs are released passively by mass action. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:01003172 | Cytoplasm | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:01003173 | Mitochondrion | HEK-293 cells|HeLa cells | 27396686 |
| RLID:01003174 | Mitochondrion | HEK-293 cells|HeLa cells | 27563705 |
| RLID:01003175 | Mitochondrion | Skeletal muscle myoblasts | 21637849 |
| RLID:01003176 | Mitochondrion | Cell line (HEK-293|HeLa) | 22984580 |
| RLID:01003177 | Nucleus | Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa) | 24918059 |
| RLID:11005221 | Exosome | Human cervical cancer cell line (HeLa) | 25760330 |
| RLID:11005222 | Exosome | Pooled sera | 27278097 |
| RLID:11005224 | Exosome | Ovarian follicular fluid | 22116803 |
| RLID:11005225 | Exosome | Brain tissue | 23382797 |
| RLID:11005226 | Exosome | Plasma | 23663360 |
| RLID:11005227 | Exosome | Serum | 25135963 |
| RLID:11005228 | Exosome | Human esophageal cancer cell line (EC9706) | 25184951 |
| RLID:11005229 | Exosome | Colon cancer cell line (LIM1863) | 25330373 |
| RLID:11005230 | Exosome | Cerebrospinal fluid | 25420022 |
| RLID:11005231 | Microvesicle | Plasma | 23077538 |
| RLID:11005232 | Microvesicle | Seminal plasma | 23539611 |
| RLID:11005233 | Microvesicle | Serum | 24797360 |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-miR-320a-5p | Parkinson disease | MNDR-E-MI-39355 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | NFKB2 | Homo sapiens | RR00998426 |
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