Detail Information

Basic Information:


  VIRBase ID:  

HHID00092966

  Virus:  

Influenza A virus (A/swine/Guangxi/NS2783/2010(H3N2))

  Host:  

Homo sapiens

  Confidence Score:  

0.9124

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-582-5p:           RPS29:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-582-5p RPS29
miRBase
Accession/Entrez ID		 MIMAT0003247 6235
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DBA13//S29//uS14

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-582-5p
rs1190339760 chr5:59703674    G/A
rs1291143355 chr5:59703672    T/A
rs1455812678 chr5:59703667    G/GT
rs753758364 chr5:59703675    T/C
rs779684016 chr5:59703670    A/C
rs779684016 chr5:59703670    A/G
rs1245677877 chr5:59703684    T/A
rs373502275 chr5:59703686    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RPS29
chr14:50043802(-) A-I      3'UTR
chr14:50051536(-) A-I      intronic
chr14:50043912(-) A-I      3'UTR
chr14:50043944(-) A-I      3'UTR
chr14:50048950(-) A-I      intronic
chr14:50051477(-) A-I      intronic
chr14:50048710(-) A-I      intronic
chr14:50050821(-) A-I      intronic
chr14:50048240(-) A-I      intronic
chr14:50045350(-) A-I      intronic
chr14:50050895(-) A-I      intronic
chr14:50048628(-) A-I      intronic
chr14:50045536(-) A-I      intronic
chr14:50048370(-) A-I      intronic
chr14:50046169(-) A-I      intronic
chr14:50045472(-) A-I      intronic
chr14:50050815(-) A-I      intronic
chr14:50052275(-) A-I      intronic
chr14:50052268(-) A-I      intronic
chr14:50050752(-) A-I      intronic
chr14:50046202(-) A-I      intronic
chr14:50050945(-) A-I      intronic
chr14:50050797(-) A-I      intronic
chr14:50050943(-) A-I      intronic
chr14:50050934(-) A-I      intronic
chr14:50050772(-) A-I      intronic
chr14:50050776(-) A-I      intronic
chr14:50050904(-) A-I      intronic
chr14:50050150(-) A-I      intronic
chr14:50051303(-) A-I      intronic
chr14:50050884(-) A-I      intronic
chr14:50050864(-) A-I      intronic
chr14:50046248(-) A-I      intronic
chr14:50043877(-) A-I      3'UTR
chr14:50043748(-) A-I      3'UTR
chr14:50043890(-) A-I      3'UTR
chr14:50043810(-) A-I      3'UTR
chr14:50043851(-) A-I      3'UTR
chr14:50043768(-) A-I      3'UTR
chr14:50043896(-) A-I      3'UTR
chr14:50043827(-) A-I      3'UTR
chr14:50043756(-) A-I      3'UTR
chr14:50043743(-) A-I      3'UTR
chr14:50043907(-) A-I      3'UTR
chr14:50043876(-) A-I      3'UTR
chr14:50045455(-) A-I      intronic
chr14:50050805(-) A-I      intronic
chr14:50050124(-) A-I      intronic
chr14:50045341(-) A-I      intronic
chr14:50050990(-) A-I      intronic
chr14:50048522(-) A-I      intronic
chr14:50051454(-) A-I      intronic
chr14:50045443(-) A-I      intronic
chr14:50045550(-) A-I      intronic
chr14:50050942(-) A-I      intronic
chr14:50048594(-) A-I      intronic
chr14:50052003(-) A-I      intronic
chr14:50051226(-) A-I      intronic
chr14:50051962(-) A-I      intronic
chr14:50050806(-) A-I      intronic
chr14:50051420(-) A-I      intronic
chr14:50051358(-) A-I      intronic
chr14:50051373(-) A-I      intronic
chr14:50050828(-) A-I      intronic
chr14:50051920(-) A-I      intronic
chr14:50051370(-) A-I      intronic
chr14:50052301(-) A-I      intronic
chr14:50045375(-) A-I      intronic
chr14:50051360(-) A-I      intronic
chr14:50050792(-) A-I      intronic
chr14:50050824(-) A-I      intronic
chr14:50048287(-) A-I      intronic
chr14:50050976(-) A-I      intronic
chr14:50048578(-) A-I      intronic
chr14:50052263(-) A-I      intronic
chr14:50051923(-) A-I      intronic
chr14:50049762(-) A-I      intronic
chr14:50051974(-) A-I      intronic
chr14:50046175(-) A-I      intronic
chr14:50045549(-) A-I      intronic
chr14:50049838(-) A-I      intronic
chr14:50051986(-) A-I      intronic
chr14:50051382(-) A-I      intronic
chr14:50049801(-) A-I      intronic
chr14:50050767(-) A-I      intronic
chr14:50050974(-) A-I      intronic
chr14:50045449(-) A-I      intronic
chr14:50046176(-) A-I      intronic
chr14:50051315(-) A-I      intronic
chr14:50046174(-) A-I      intronic
chr14:50045456(-) A-I      intronic
chr14:50051290(-) A-I      intronic
chr14:50045448(-) A-I      intronic
chr14:50050894(-) A-I      intronic
chr14:50043850(-) A-I      3'UTR
chr14:50043716(-) A-I      3'UTR
chr14:50043755(-) A-I      3'UTR
chr14:50043949(-) A-I      3'UTR
chr14:50043715(-) A-I      3'UTR
chr14:50043837(-) A-I      3'UTR
chr14:50043742(-) A-I      3'UTR
chr14:50043883(-) A-I      3'UTR
chr14:50043811(-) A-I      3'UTR
chr14:50043794(-) A-I      3'UTR
chr14:50043819(-) A-I      3'UTR
chr14:50043859(-) A-I      3'UTR
chr14:50043730(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RPS29
chr14:50051454(-) A-I intron -    21960545   //22327324
chr14:50050974(-) A-I intron -    21960545
chr14:50050990(-) A-I intron -    21960545
chr14:50051382(-) A-I intron -    21960545
chr14:50050294(-) C-A exon 3'UTR    21725310
chr14:50051290(-) A-G intron -    22484847
chr14:50051382(-) A-G intron -    22484847
chr14:50051454(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RPS29
chr14:50043532-50043533(-) m6A 3'UTR       22608085
chr14:50043626-50043627(-) m6A 3'UTR       22608085
chr14:50044017-50044018(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044031-50044032(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044038-50044039(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044047-50044048(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044053-50044054(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044062-50044063(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044071-50044072(-) m6A 3'UTR       24981863//28052920//27773535//22608085
chr14:50044108-50044109(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044197-50044198(-) m6A 3'UTR       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr14:50044321-50044322(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044329-50044330(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044404-50044405(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044438-50044439(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044447-50044448(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50044497-50044498(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr14:50050363-50050364(-) Tm 3'UTR//exon//intron       -
chr14:50052752-50052753(-) m6A CDS//exon       22575960
chr14:50052788-50052789(-) m6A exon//intron       22575960
chr14:50065015-50065016(-) m6A exon//intron       25456834
chr14:50065058-50065059(-) m6A exon//intron       25456834//27773535
chr14:50065067-50065068(-) m6A exon//intron       25456834//27773535
chr14:50065137-50065138(-) m6A CDS//exon       24284625//25456834//27773535
chr14:50065286-50065287(-) m6A 5'UTR//exon       24284625//25456834//24981863//22575960
chr14:50065474-50065475(-) m6A exon       24981863//22608085
chr14:50065508-50065509(-) m6A exon       24981863//22608085
chr14:50065618-50065619(-) m6A exon       24284625//25456834//24981863//22608085
chr14:50065698-50065699(-) m6A exon       24284625//25456834//24981863//22608085
chr14:50065865-50065866(-) m6A exon       24284625//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-582-5p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Plasma     23663360
Exosome Serum     25349172
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
RPS29
Chromatin K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-582-5p
Iodine Green 9956454 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Secalonic acid D 73431 Drug sensitive
1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive
6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive
Herveline O 5459269 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Staurosporine, 98% 49831000 Drug resistant
Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive
o6-Benzylguanine 4578 Drug resistant
Triciribine phosphate 43860 Drug resistant
Aminopyrimidine-CH3 406278 Drug sensitive
Aminopyrimidine-F 406276 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
Hookerianamide J 25016666 Drug sensitive
Antimycin A3 245869 Drug sensitive
Kinetin riboside 20345 Drug resistant
4-[[(1-Benzylpyrazolo[3,4-d]pyrimidin-4-yl)hydrazinylidene]methyl]-2-methoxyphenol 136091540 Drug resistant
Astrazon Orange R 135747272 Drug sensitive
1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant
tunicamycin - Drug resistant
(z) 4-acetoxy-(3,4',5)-trimethoxystilbene - Drug sensitive
2k2S,S? - Drug sensitive
4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
dichlorobisoxinatotitanium(iv) - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-582-5p
Formaldehyde 712 Drug interaction    RC00006017
Alocrest 60780 Drug interaction    RC00006022
Vincristine 5978 Drug interaction    RC00006020
Sunitinib 5329102 Drug interaction    RC00006023
Doxorubicin 31703 Drug interaction    RC00006021
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00006019
Verapamil 2520 Drug interaction    RC00006018
Navitoclax 24978538 Drug interaction    RC00006024
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-582-5p
Cisplatin 5702198       21575166
Sirolimus 5284616       30666128
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-582-5p
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
l-685,458       5479543
Selumetinib       10127622

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-582-5p
Interactor2: RPS29

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence Deep sequencing//Microarray
Prediction-Evidence microRNA.org//PITA//Targetscan
Support Database ViRBase

References:


PMID 31207403 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Relationships between 4 miRNAs and 5 inversely correlated target genes selected in qRT-PCR.

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