Basic Information:

  VIRBase ID:  

HHID00066020

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-186-3p:  MIMAT0004612          WDR17:  NM_170710     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-186-3p	WDR17
miRBase Accession/Entrez ID	MIMAT0004612	116966
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-186-3p	rs1241044041 chr1:71067653    C/T rs1318830037 chr1:71067663    C/A rs1318830037 chr1:71067663    C/T rs771255877 chr1:71067645    A/C rs776722712 chr1:71067655    C/T rs934513177 chr1:71067651    T/C rs1292420312 chr1:71067659    T/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WDR17	chr4:177067459(+) A-I      intronic chr4:177067436(+) A-I      intronic chr4:177067410(+) A-I      intronic chr4:176992674(+) A-I      intronic chr4:176992713(+) A-I      intronic chr4:177029989(+) A-I      intronic chr4:177073265(+) A-I      intronic chr4:177073271(+) A-I      intronic chr4:176989495(+) A-I      ncRNA chr4:177064538(+) A-I      intronic chr4:176997028(+) A-I      intronic chr4:177076796(+) A-I      intronic chr4:177064775(+) A-I      intronic chr4:176989593(+) A-I      intronic chr4:176997036(+) A-I      intronic chr4:176989575(+) A-I      intronic chr4:177064774(+) A-I      intronic chr4:177073343(+) A-I      intronic chr4:177064587(+) A-I      intronic chr4:177064633(+) A-I      intronic chr4:177064131(+) A-I      intronic chr4:177064087(+) A-I      intronic chr4:177064135(+) A-I      intronic chr4:177064812(+) A-I      intronic chr4:177064732(+) A-I      intronic chr4:176997102(+) A-I      intronic chr4:177074073(+) A-I      intronic chr4:177064079(+) A-I      intronic chr4:177073544(+) A-I      intronic chr4:177073347(+) A-I      intronic chr4:176996983(+) A-I      intronic chr4:177009554(+) A-I      intronic chr4:176992639(+) A-I      intronic chr4:177076765(+) A-I      intronic chr4:177091567(+) A-I      intronic chr4:177064755(+) A-I      intronic chr4:177064577(+) A-I      intronic chr4:177073464(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	WDR17	chr4:177100938-177100939(+) m6A 3'UTR       24981863 chr4:177100968-177100969(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-186-3p	Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	WDR17	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-186-3p
Interactor2: WDR17

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.