Detail

Basic Information:

VIRBase ID:

HHID00065664

Virus:

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

Host:

Homo sapiens

Confidence Score:

0.4752

Interaction Type:

Host-Host interaction

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-let-7g-3p	RPS3P3
miRBase Accession/Entrez ID	MIMAT0004584	440991
Organism	Homo sapiens	Homo sapiens
Category	miRNA	pseudo
Alias	-	RPS3_1_443

ncRNA SNP information:

Resource

Symbol

SNP ID

SNP Position

Ref/Alt

miRNASNP-v3

hsa-let-7g-3p

rs1022640944	chr3:52268290	G/A
rs1166657040	chr3:52268299	A/G
rs1356748432	chr3:52268293	C/G

RNA Localization:

Resource

Symbol

Subcellular Localization

Tissue or Cell Line

PMID

RNALocate

hsa-let-7g-3p

Exosome	Breast milk	22211110
Exosome	Brain tissue	23382797
Exosome	Plasma	23663360
Exosome	Serum	24683445
Exosome	Breast milk\|Cell lines\|Epididymal epithelial cells\|Osteoblast\|Plasma\|Primary glioblastoma neurosphere cells\|Primary keratinocyte\|Saliva\|Serum\|Urine	-
Microvesicle	Cerebrospinal fluid	24797360
Microvesicle	Colon cancer cell line (LIM1863)\|Mesenchymal stem cells	-

RPS3P3

Exosome

Blood

-

Interaction Network (The top 100 interactions):

Interactor1: hsa-let-7g-3p

Interactor2: RPS3P3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.