Basic Information
| RNALocate ID: | RLID:11003697 |
| RNA Symbol: | hsa-let-7g-3p |
| Localization: | Exosome |
RNA Information
| RNA Name: | hsa-let-7g-3p |
| RNA ID: | miRBase:MIMAT0004584 |
| RNA Category: | miRNA |
| Species: | Homo sapiens |
Localization Information
| PubMed ID: | 22211110 |
| Tissue/Cell Line: | Breast milk |
| Method: | Next-generation RNA sequencing |
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The expression profile of selected miRNAs in breast milk exosomes. Originally published in Int J Biol Sci. Zhou Q, et al, 2012. Reproduced under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) |
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| Description: | Distribution and characterization of miRNAs in breast milk exosomes. (A) Distribution of pre-miRNAs. Out of 1,424 pre-miRNAs deposited in miRBase 17.0 (blue circle), 87 (6.11%) pre-miRNAs have been designated as immune-related pre-miRNAs based on annotation in the Pathway Central database (SABiosciences, MD, USA). Immune-related pre-miRNAs (59 of 452, 13.05%) are enriched in breast milk exosomes (red circle). χ2 test: Number of immune-related miRNAs and others detected in breast milk exosomes compared with the total entries in miRBase 17.0. (B) Top ten most highly expressed unique miRNAs. Plot of the unique miRNAs (starting from the miRNA with the highest counts, x-axis) versus their cumulative % of the total counts from 602 unique miRNAs detected in breast milk exosomes for each small RNA library. Values are means ± s.d. The dashed horizontal line at 62.3% represents the level of the top ten unique miRNAs and the % of individual miRNAs is marked by the gray line. (C-E) The expression profile of selected miRNAs in breast milk exosomes. (C) 59 immune-related pre-miRNAs; (D) miR-17-92 cluster and paralogous clusters, and (E) ten well-characterized tissue-specific pre-miRNAs. Data are collected from Figure 2. |
Other Subcellular Localization
| RNALocate ID | Localization | Tissue/Cell line | PubMed ID |
| RLID:11003698 | Exosome | Brain tissue | 23382797 |
| RLID:11003699 | Exosome | Plasma | 23663360 |
| RLID:11003700 | Exosome | Serum | 24683445 |
| RLID:11003701 | Microvesicle | Cerebrospinal fluid | 24797360 |
| RLID-D:11000617 | Microvesicle | Colon cancer cell line (LIM1863)|Mesenchymal stem cells | |
| RLID-D:11001494 | Exosome | Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine |
ncRNA Disease Information
| Resource | RNA Symbol | Disease | Link |
| MNDR | hsa-let-7g-3p | Oral squamous cell carcinoma | MNDR-E-MI-01938 |
| MNDR | hsa-let-7g-3p | Medulloblastoma | MNDR-E-MI-01939 |
| MNDR | hsa-let-7g-3p | Uterine corpus endometrial carcinoma | MNDR-E-MI-01940 |
| MNDR | hsa-let-7g-3p | Estrogen-receptor positive breast cancer | MNDR-E-MI-01941 |
| MNDR | hsa-let-7g-3p | Estrogen-receptor negative breast cancer | MNDR-E-MI-01942 |
| MNDR | hsa-let-7g-3p | Progesterone-receptor positive breast cancer | MNDR-E-MI-01943 |
| MNDR | hsa-let-7g-3p | Progesterone-receptor negative breast cancer | MNDR-E-MI-01944 |
| MNDR | hsa-let-7g-3p | Her2-receptor positive breast cancer | MNDR-E-MI-01945 |
| MNDR | hsa-let-7g-3p | Gastric cancer | MNDR-E-MI-01946 |
| MNDR | hsa-let-7g-3p | Alzheimer disease | MNDR-E-MI-01947 |
| MNDR | hsa-let-7g-3p | Lung cancer | MNDR-E-MI-01948 |
| MNDR | hsa-let-7g-3p | Metabolic syndrome x | MNDR-E-MI-01949 |
| MNDR | hsa-let-7g-3p | Parkinson disease | MNDR-E-MI-01950 |
| MNDR | hsa-let-7g-3p | Breast cancer | MNDR-E-MI-01951 |
| MNDR | hsa-let-7g-3p | Pancreatic cancer | MNDR-E-MI-01952 |
| MNDR | hsa-let-7g-3p | Rectum adenocarcinoma | MNDR-E-MI-01953 |
| MNDR | hsa-let-7g-3p | Colon adenocarcinoma | MNDR-E-MI-01954 |
| MNDR | hsa-let-7g-3p | West nile virus infection | MNDR-E-MI-01955 |
| MNDR | hsa-let-7g-3p | Relapsing-remitting multiple sclerosis | MNDR-E-MI-01956 |
| MNDR | hsa-let-7g-3p | Familial ovarian cancer | MNDR-E-MI-01957 |
| MNDR | hsa-let-7g-3p | Prostate adenocarcinoma | MNDR-E-MI-01958 |
| MNDR | hsa-let-7g-3p | Carcinoma ductal breast | MNDR-E-MI-01959 |
| MNDR | hsa-let-7g-3p | Amyotrophic lateral sclerosis | MNDR-E-MI-01960 |
| MNDR | hsa-let-7g-3p | Liver cancer | MNDR-E-MI-01961 |
| MNDR | hsa-let-7g-3p | Lung squamous cell carcinoma | MNDR-E-MI-01962 |
| MNDR | hsa-let-7g-3p | Lung adenocarcinoma | MNDR-E-MI-01963 |
| MNDR | hsa-let-7g-3p | Bladder urothelial carcinoma | MNDR-E-MI-01964 |
| MNDR | hsa-let-7g-3p | Carcinoma renal cell | MNDR-E-MI-01965 |
| MNDR | hsa-let-7g-3p | Kidney renal papillary cell carcinoma | MNDR-E-MI-01966 |
| MNDR | hsa-let-7g-3p | Cholangiocarcinoma | MNDR-E-MI-01967 |
| MNDR | hsa-let-7g-3p | Head and neck squamous cell carcinoma | MNDR-E-MI-01968 |
| MNDR | hsa-let-7g-3p | Breast invasive carcinoma | MNDR-E-MI-01969 |
| MNDR | hsa-let-7g-3p | Hepatocellular carcinoma | MNDR-E-MI-01970 |
| MNDR | hsa-let-7g-3p | Familiar ovarian carcinoma | MNDR-E-MI-01971 |
| MNDR | hsa-let-7g-3p | Malignant pleural mesothelioma | MNDR-E-MI-01972 |
| MNDR | hsa-let-7g-3p | Neuroblastoma | MNDR-E-MI-01973 |
| MNDR | hsa-let-7g-3p | Chronic fatigue syndrome | MNDR-E-MI-01974 |
| MNDR | hsa-let-7g-3p | Skin cutaneous melanoma | MNDR-E-MI-01975 |
| MNDR | hsa-let-7g-3p | Skin melanoma | MNDR-E-MI-01976 |
| MNDR | hsa-let-7g-3p | Colorectal cancer | MNDR-E-MI-01977 |
| MNDR | hsa-let-7g-3p | Nasopharynx carcinoma | MNDR-E-MI-01978 |
| MNDR | hsa-let-7g-3p | Multiple myeloma | MNDR-E-MI-01979 |
| MNDR | hsa-let-7g-3p | Nasopharyngeal cancer | MNDR-E-MI-01980 |
| MNDR | hsa-let-7g-3p | Breast cancer her3+ negative | MNDR-E-MI-01981 |
RNA Interaction Information
| Resource | RNA Symbol | Species | Link | RNALocate ID |
| RNAInter | CASP3 | Homo sapiens | RR00279011 |
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