Detail Information

Basic Information:


  VIRBase ID:  

HHID00065660

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:           TOP1MT:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7g-3p TOP1MT
miRBase
Accession/Entrez ID		 MIMAT0004584 116447
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7g-3p
rs1022640944 chr3:52268290    G/A
rs1166657040 chr3:52268299    A/G
rs1356748432 chr3:52268293    C/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TOP1MT
chr8:144393406(-) A-I      intronic
chr8:144393394(-) A-I      intronic
chr8:144415474(-) A-I      intronic
chr8:144393214(-) A-I      intronic
chr8:144393342(-) A-I      intronic
chr8:144393131(-) A-I      intronic
chr8:144393271(-) A-I      intronic
chr8:144393728(-) A-I      intronic
chr8:144402637(-) A-I      intronic
chr8:144393334(-) A-I      intronic
chr8:144393864(-) A-I      intronic
chr8:144402258(-) A-I      intronic
chr8:144393405(-) A-I      intronic
chr8:144396652(-) A-I      intronic
chr8:144393411(-) A-I      intronic
chr8:144393269(-) A-I      intronic
chr8:144393804(-) A-I      intronic
chr8:144395161(-) A-I      intronic
chr8:144395582(-) A-I      intronic
chr8:144393661(-) A-I      intronic
chr8:144396597(-) A-I      intronic
chr8:144402061(-) A-I      intronic
chr8:144395186(-) A-I      intronic
chr8:144393753(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TOP1MT
chr8:144393313(-) T-A intron -    22484847
chr8:144393753(-) A-G intron -    22484847
chr8:144393796(-) T-C intron -    22484847
chr8:144393816(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TOP1MT
chr8:144391592-144391593(-) m6A 3'UTR//exon       27773535//27773536
chr8:144391623-144391624(-) m6A CDS//exon       27773535//27773536
chr8:144391669-144391670(-) m6A CDS//exon       27773535//27773536
chr8:144392258-144392259(-) m6A CDS//exon       24209618//27773535//27371828//27773536
chr8:144392300-144392301(-) m6A CDS//exon       24284625//24209618//25456834//27773535//27371828//27773536
chr8:144392312-144392313(-) m6A CDS//exon       24284625//24209618//25456834//27773535//27371828//27773536
chr8:144392373-144392374(-) m1A CDS//exon       26863196
chr8:144392491-144392492(-) m6A exon//intron       24284625//25456834//27773536
chr8:144398289-144398290(-) m6A 3'UTR//CDS       24209618//27773535//27773536
chr8:144399943-144399944(-) m6A 3'UTR//CDS       27773535//27773536
chr8:144399993-144399994(-) m6A 3'UTR//CDS       27773535//27773536
chr8:144400023-144400024(-) m6A 3'UTR//CDS//intron       27773536
chr8:144400218-144400219(-) m6A 3'UTR//CDS       27773535
chr8:144400224-144400225(-) m6A 3'UTR//CDS       27773535
chr8:144400245-144400246(-) m6A 3'UTR//CDS       27773535
chr8:144403410-144403411(-) m6A 3'UTR//CDS       27773535
chr8:144406201-144406202(-) m6A 3'UTR//CDS       -
chr8:144406284-144406285(-) m6A 3'UTR//CDS       27371828
chr8:144406305-144406306(-) m6A 3'UTR//CDS       27371828
chr8:144406673-144406674(-) m6A 3'UTR//CDS       27371828
chr8:144406697-144406698(-) m6A 3'UTR//CDS       24209618
chr8:144406713-144406714(-) m6A 3'UTR//CDS       24209618
chr8:144406796-144406797(-) m6A 3'UTR//CDS       24284625//24209618
chr8:144407679-144407680(-) m6A 3'UTR//CDS//intron       24209618//24981863//27773535//27371828//27773536
chr8:144408434-144408435(-) m6A 3'UTR//CDS       24209618//24981863//27773535//27371828//27773536
chr8:144408473-144408474(-) m6A 3'UTR//CDS       24209618//24981863//27773535//27371828//27773536
chr8:144409503-144409504(-) m6A 3'UTR//intron       24209618//24981863//27773535//27371828
chr8:144409584-144409585(-) m6A 3'UTR//intron       27773535
chr8:144409590-144409591(-) m6A 3'UTR//intron       27773535
chr8:144410443-144410444(-) m6A 3'UTR//intron       24209618
chr8:144411541-144411542(-) m6A CDS       24209618//27773535
chr8:144413469-144413470(-) m6A 5'UTR//CDS       24209618//27773535//27371828//27773536
chr8:144413962-144413963(-) m6A 5'UTR//intron       24981863//27773535//27371828//27773536
chr8:144416390-144416391(-) m6A 5'UTR//intron       -
chr8:144442075-144442076(-) m6A 5'UTR//exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7g-3p
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
TOP1MT
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7g-3p
Interactor2: TOP1MT

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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