Detail Information

Basic Information:


  VIRBase ID:  

HHID00065658

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:           LMNB2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7g-3p LMNB2
miRBase
Accession/Entrez ID		 MIMAT0004584 84823
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EPM9//LAMB2//LMN2//MCPH27

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7g-3p
rs1022640944 chr3:52268290    G/A
rs1166657040 chr3:52268299    A/G
rs1356748432 chr3:52268293    C/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LMNB2
chr19:2449614(-) A-I      intronic
chr19:2449561(-) A-I      intronic
chr19:2449099(-) A-I      intronic
chr19:2449098(-) A-I      intronic
chr19:2449091(-) A-I      intronic
chr19:2449002(-) A-I      intronic
chr19:2448724(-) A-I      intronic
chr19:2448664(-) A-I      intronic
chr19:2448652(-) A-I      intronic
chr19:2442490(-) A-I      intronic
chr19:2442483(-) A-I      intronic
chr19:2442261(-) A-I      intronic
chr19:2439901(-) A-I      intronic
chr19:2439900(-) A-I      intronic
chr19:2439896(-) A-I      intronic
chr19:2439154(-) A-I      intronic
chr19:2451201(-) A-I      intronic
chr19:2451185(-) A-I      intronic
chr19:2450917(-) A-I      intronic
chr19:2450721(-) A-I      intronic
chr19:2450708(-) A-I      intronic
chr19:2450698(-) A-I      intronic
chr19:2450610(-) A-I      intronic
chr19:2450593(-) A-I      intronic
chr19:2450471(-) A-I      intronic
chr19:2450443(-) A-I      intronic
chr19:2449737(-) A-I      intronic
chr19:2449653(-) A-I      intronic
chr19:2442445(-) A-I      intronic
chr19:2442333(-) A-I      intronic
chr19:2451090(-) A-I      intronic
chr19:2450812(-) A-I      intronic
chr19:2448672(-) A-I      intronic
chr19:2442294(-) A-I      intronic
chr19:2449170(-) A-I      intronic
chr19:2448656(-) A-I      intronic
chr19:2450520(-) A-I      intronic
chr19:2449043(-) A-I      intronic
chr19:2442467(-) A-I      intronic
chr19:2451127(-) A-I      intronic
chr19:2450564(-) A-I      intronic
chr19:2450770(-) A-I      intronic
chr19:2442676(-) A-I      intronic
chr19:2451190(-) A-I      intronic
chr19:2450994(-) A-I      intronic
chr19:2450482(-) A-I      intronic
chr19:2442281(-) A-I      intronic
chr19:2448602(-) A-I      intronic
chr19:2450846(-) A-I      intronic
chr19:2450794(-) A-I      intronic
chr19:2442243(-) A-I      intronic
chr19:2450492(-) A-I      intronic
chr19:2449007(-) A-I      intronic
chr19:2448746(-) A-I      intronic
chr19:2450497(-) A-I      intronic
chr19:2442232(-) A-I      intronic
chr19:2451073(-) A-I      intronic
chr19:2450824(-) A-I      intronic
chr19:2439869(-) A-I      intronic
chr19:2451115(-) A-I      intronic
chr19:2442669(-) A-I      intronic
chr19:2450907(-) A-I      intronic
chr19:2450768(-) A-I      intronic
chr19:2450541(-) A-I      intronic
chr19:2442237(-) A-I      intronic
chr19:2442698(-) A-I      intronic
chr19:2440285(-) A-I      intronic
chr19:2450825(-) A-I      intronic
chr19:2448813(-) A-I      intronic
chr19:2448722(-) A-I      intronic
chr19:2439828(-) A-I      intronic
chr19:2449519(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED LMNB2
chr19:2449027(-) A-G intron -    22484847
chr19:2449040(-) A-G intron -    22484847
chr19:2449043(-) A-G intron -    22484847
chr19:2449170(-) A-G intron -    22484847
chr19:2450436(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LMNB2
chr19:2428176-2428177(-) m6A 3'UTR//intron       24284625//27773535//22608085
chr19:2428201-2428202(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr19:2428296-2428297(-) m6A 3'UTR//intron       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr19:2428409-2428410(-) m6A 3'UTR//intron       24284625//25456834//24981863//27371828//27773536//22608085
chr19:2428593-2428594(-) m6A 3'UTR//intron       24284625//24981863//27773536//22575960
chr19:2428697-2428698(-) m6A 3'UTR//intron       24284625
chr19:2428754-2428755(-) m6A 3'UTR//intron       24284625
chr19:2428799-2428800(-) m6A 3'UTR//intron       24981863
chr19:2428851-2428852(-) m6A 3'UTR//intron       24981863
chr19:2428893-2428894(-) m6A 3'UTR//intron       24981863
chr19:2428941-2428942(-) m6A 3'UTR//intron       24981863
chr19:2428964-2428965(-) m6A 3'UTR//intron       24981863
chr19:2429206-2429207(-) m6A 3'UTR//intron       24981863
chr19:2429247-2429248(-) m6A 3'UTR//intron       24981863
chr19:2429452-2429453(-) m6A 3'UTR//intron       24284625//27773536
chr19:2429526-2429527(-) m6A 3'UTR//exon//intron       24284625//27773536
chr19:2429622-2429623(-) m6A 3'UTR//exon//intron       24284625//27773536
chr19:2429630-2429631(-) m6A 3'UTR//exon//intron       24284625
chr19:2429721-2429722(-) m6A 3'UTR//exon//intron       24284625//27773535
chr19:2429921-2429922(-) m6A 3'UTR//exon//intron       24284625//24981863//27773535
chr19:2429935-2429936(-) m6A 3'UTR//exon//intron       24284625//27773535
chr19:2430084-2430085(-) m6A 3'UTR//exon//intron       27773535
chr19:2430126-2430127(-) m6A 3'UTR//exon//intron       24981863//27773535
chr19:2430167-2430168(-) m6A 3'UTR//exon//intron       24209618//24981863//27773535
chr19:2430183-2430184(-) m6A 3'UTR//exon//intron       24209618//24981863//27773535
chr19:2430205-2430206(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828
chr19:2430284-2430285(-) m6A 3'UTR//exon//intron       24284625//24209618//24981863//27773535//27371828
chr19:2430320-2430321(-) Y 3'UTR//intron       26075521
chr19:2430412-2430413(-) m6A 3'UTR//intron       24284625//24209618//24981863//27371828//27773536//22608085
chr19:2430421-2430422(-) m6A 3'UTR//intron       24284625//24209618//24981863//27371828//27773536//22608085
chr19:2430494-2430495(-) m6A 3'UTR//intron       24284625//24209618//24981863//27371828//27773536//22608085
chr19:2430543-2430544(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr19:2430578-2430579(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr19:2430640-2430641(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr19:2430703-2430704(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr19:2430797-2430798(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536
chr19:2430859-2430860(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr19:2430907-2430908(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr19:2430937-2430938(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chr19:2430945-2430946(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chr19:2431631-2431632(-) m1A CDS//exon//intron       26863196
chr19:2431640-2431641(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//27773536
chr19:2432504-2432505(-) m6A CDS//exon       24284625//24209618//27773536
chr19:2433827-2433828(-) m6A CDS//exon       24284625//24209618//27773536
chr19:2433836-2433837(-) m6A CDS//exon       24284625//24209618//27773536
chr19:2434340-2434341(-) m6A CDS//exon       24284625//24209618//27371828//27773536
chr19:2434454-2434455(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960
chr19:2434906-2434907(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536
chr19:2435012-2435013(-) m6A CDS//exon       24284625//24209618//24981863//27371828//27773536//22575960
chr19:2435119-2435120(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960
chr19:2436897-2436898(-) m6A exon//intron       24284625//24209618//25456834//27773535//27371828//27773536
chr19:2436920-2436921(-) m6A exon//intron       27371828//27773536
chr19:2436968-2436969(-) m6A exon//intron       27773536
chr19:2436983-2436984(-) m6A exon//intron       -
chr19:2436992-2436993(-) m6A exon//intron       -
chr19:2438185-2438186(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536
chr19:2438215-2438216(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536
chr19:2438224-2438225(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr19:2438478-2438479(-) m6A CDS       24284625//24209618//24981863//27371828//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7g-3p
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
LMNB2
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7g-3p
Interactor2: LMNB2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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