Basic Information:

  VIRBase ID:  

HHID00065655

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:  MIMAT0004584          DLGAP3:  NM_001080418     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-let-7g-3p	DLGAP3
miRBase Accession/Entrez ID	MIMAT0004584	58512
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DAP3//SAPAP3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-let-7g-3p	rs1022640944 chr3:52268290    G/A rs1166657040 chr3:52268299    A/G rs1356748432 chr3:52268293    C/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DLGAP3	chr1:35385162(-) A-I      intronic chr1:35352785(-) A-I      intronic chr1:35359694(-) A-I      intronic chr1:35358230(-) A-I      intronic chr1:35352798(-) A-I      intronic chr1:35352753(-) A-I      intronic chr1:35345832(-) A-I      intronic chr1:35383057(-) A-I      intronic chr1:35343714(-) A-I      intronic chr1:35360724(-) A-I      intronic chr1:35364848(-) A-I      intronic chr1:35352831(-) A-I      intronic chr1:35347971(-) A-I      intronic chr1:35360712(-) A-I      intronic chr1:35358239(-) A-I      intronic chr1:35346194(-) A-I      intronic chr1:35377694(-) A-I      intronic chr1:35383087(-) A-I      intronic chr1:35345854(-) A-I      intronic chr1:35383221(-) A-I      intronic chr1:35364958(-) A-I      intronic chr1:35364875(-) A-I      intronic chr1:35382572(-) A-I      intronic chr1:35364849(-) A-I      intronic chr1:35360779(-) A-I      intronic chr1:35360755(-) A-I      intronic chr1:35345874(-) A-I      intronic chr1:35343825(-) A-I      intronic chr1:35382145(-) A-I      intronic chr1:35383077(-) A-I      intronic chr1:35359762(-) A-I      intronic chr1:35343740(-) A-I      intronic chr1:35376679(-) A-I      intronic chr1:35376759(-) A-I      intronic chr1:35383166(-) A-I      intronic chr1:35346197(-) A-I      intronic chr1:35347957(-) A-I      intronic chr1:35358270(-) A-I      intronic chr1:35362068(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DLGAP3	chr1:35331041-35331042(-) m6A 3'UTR       25456834 chr1:35331165-35331166(-) m6A 3'UTR       25456834 chr1:35331176-35331177(-) m6A 3'UTR       25456834 chr1:35331190-35331191(-) m6A 3'UTR       25456834 chr1:35331813-35331814(-) m6A CDS       25456834//27371828 chr1:35331822-35331823(-) m6A CDS       25456834//27371828 chr1:35369894-35369895(-) m6A CDS       25456834 chr1:35369912-35369913(-) m6A CDS       25456834 chr1:35370012-35370013(-) m6A CDS       25456834 chr1:35370091-35370092(-) m6A CDS       25456834 chr1:35370181-35370182(-) m6A CDS       25456834//24981863 chr1:35370247-35370248(-) m6A CDS       24209618//25456834//24981863//27371828//27773536 chr1:35370358-35370359(-) m6A CDS       25456834//27773536 chr1:35370403-35370404(-) m6A CDS       25456834 chr1:35370673-35370674(-) m6A CDS       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-let-7g-3p	Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Serum     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cerebrospinal fluid     24797360 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	DLGAP3	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-let-7g-3p
Interactor2: DLGAP3

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.