Basic Information:

  VIRBase ID:  

HHID00065654

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:  MIMAT0004584          RBAK:  NM_001204456     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-let-7g-3p	RBAK
miRBase Accession/Entrez ID	MIMAT0004584	57786
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ZNF769

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-let-7g-3p	rs1022640944 chr3:52268290    G/A rs1166657040 chr3:52268299    A/G rs1356748432 chr3:52268293    C/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RBAK	chr7:5086849(+) A-I      intronic chr7:5086870(+) A-I      intronic chr7:5086875(+) A-I      intronic chr7:5089679(+) A-I      intronic chr7:5093826(+) A-I      intronic chr7:5093860(+) A-I      intronic chr7:5093916(+) A-I      intronic chr7:5094317(+) A-I      intronic chr7:5094595(+) A-I      intronic chr7:5094622(+) A-I      intronic chr7:5094674(+) A-I      intronic chr7:5094687(+) A-I      intronic chr7:5095679(+) A-I      intronic chr7:5095839(+) A-I      intronic chr7:5099045(+) A-I      intronic chr7:5099052(+) A-I      intronic chr7:5099092(+) A-I      intronic chr7:5101156(+) A-I      intronic chr7:5101309(+) A-I      intronic chr7:5101320(+) A-I      intronic chr7:5101409(+) A-I      intronic chr7:5090236(+) A-I      intronic chr7:5086758(+) A-I      intronic chr7:5101142(+) A-I      intronic chr7:5086866(+) A-I      intronic chr7:5087424(+) A-I      intronic chr7:5089742(+) A-I      intronic chr7:5094592(+) A-I      intronic chr7:5101273(+) A-I      intronic chr7:5094675(+) A-I      intronic chr7:5095856(+) A-I      intronic chr7:5095872(+) A-I      intronic chr7:5094335(+) A-I      intronic chr7:5101106(+) A-I      intronic chr7:5093782(+) A-I      intronic chr7:5095949(+) A-I      intronic chr7:5093788(+) A-I      intronic chr7:5087352(+) A-I      intronic chr7:5099031(+) A-I      intronic chr7:5093821(+) A-I      intronic chr7:5086797(+) A-I      intronic chr7:5101112(+) A-I      intronic chr7:5095978(+) A-I      intronic chr7:5086915(+) A-I      intronic chr7:5086919(+) A-I      intronic chr7:5086990(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RBAK	chr7:5085673-5085674(+) m6A 5'UTR//intron       24209618 chr7:5085860-5085861(+) m6A 5'UTR//intron       - chr7:5085912-5085913(+) m6A 5'UTR       - chr7:5085930-5085931(+) m6A 5'UTR       - chr7:5085940-5085941(+) m6A 5'UTR       - chr7:5087711-5087712(+) m6A CDS       - chr7:5096986-5096987(+) m6A CDS//exon       - chr7:5097028-5097029(+) m6A CDS//exon       - chr7:5103373-5103374(+) m6A CDS//exon       24981863 chr7:5103411-5103412(+) m6A CDS//exon       24981863 chr7:5103459-5103460(+) m6A CDS//exon       24981863//22608085 chr7:5103564-5103565(+) m6A CDS       24981863//26404942//27773535//22608085 chr7:5103569-5103570(+) m6A CDS       24981863//26404942//27773535//22608085 chr7:5103597-5103598(+) m6A CDS       24981863//26404942//27773535//22608085 chr7:5103695-5103696(+) m6A CDS       24284625//24981863//22608085 chr7:5103730-5103731(+) m6A CDS       24284625//24981863//22608085 chr7:5103803-5103804(+) m6A CDS       24284625//24981863//22608085 chr7:5103808-5103809(+) m6A CDS       24284625//24981863//22608085 chr7:5103947-5103948(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5103993-5103994(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104059-5104060(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104098-5104099(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:5104115-5104116(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:5104143-5104144(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:5104158-5104159(+) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr7:5104266-5104267(+) m6A CDS       24209618//24981863//22608085 chr7:5104350-5104351(+) m6A CDS       24981863 chr7:5104508-5104509(+) m6A CDS       24981863 chr7:5104641-5104642(+) m6A CDS       22608085 chr7:5104754-5104755(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104781-5104782(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104809-5104810(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104838-5104839(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104865-5104866(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5104949-5104950(+) m6A CDS       24284625//27773535//22608085 chr7:5104996-5104997(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5105033-5105034(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5105100-5105101(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5105117-5105118(+) m6A CDS       24284625//24981863//27773535//22608085 chr7:5105255-5105256(+) m6A 3'UTR       24284625//24981863//22608085 chr7:5105441-5105442(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr7:5106474-5106475(+) m6A 3'UTR       24981863//22608085 chr7:5106479-5106480(+) m6A 3'UTR       24981863//22608085 chr7:5106489-5106490(+) m6A 3'UTR       24981863//22608085 chr7:5106615-5106616(+) m6A 3'UTR       24981863//22608085 chr7:5106675-5106676(+) m6A 3'UTR       24981863//22608085 chr7:5106697-5106698(+) m6A 3'UTR       24981863//22608085 chr7:5106703-5106704(+) m6A 3'UTR       24981863//22608085 chr7:5106713-5106714(+) m6A 3'UTR       24981863//22608085 chr7:5106740-5106741(+) m6A 3'UTR       24981863//22608085 chr7:5106768-5106769(+) m6A 3'UTR       24981863//22608085 chr7:5106815-5106816(+) m6A 3'UTR       24981863//22608085 chr7:5106828-5106829(+) m6A 3'UTR       24981863//22608085 chr7:5106847-5106848(+) m6A 3'UTR       24981863//22608085 chr7:5106879-5106880(+) m6A 3'UTR       24981863//22608085 chr7:5106992-5106993(+) m6A 3'UTR       24981863//22608085 chr7:5107081-5107082(+) m6A 3'UTR       24981863//22608085 chr7:5107132-5107133(+) m6A 3'UTR       24981863//22608085 chr7:5107143-5107144(+) m6A 3'UTR       24981863//22608085 chr7:5107277-5107278(+) m6A 3'UTR       24981863//22608085 chr7:5107308-5107309(+) m6A 3'UTR       24981863//22608085 chr7:5107365-5107366(+) m6A 3'UTR       22608085 chr7:5107378-5107379(+) m6A 3'UTR       22608085 chr7:5107401-5107402(+) m6A 3'UTR       22608085 chr7:5107583-5107584(+) m6A 3'UTR       22608085 chr7:5107621-5107622(+) m6A 3'UTR       24981863//22608085 chr7:5107651-5107652(+) m6A 3'UTR       24981863//22608085 chr7:5107671-5107672(+) m6A 3'UTR       24981863//22608085 chr7:5107690-5107691(+) m6A 3'UTR       24981863//22608085 chr7:5107709-5107710(+) m6A 3'UTR       24981863//22608085 chr7:5107789-5107790(+) m6A 3'UTR       22608085 chr7:5107919-5107920(+) m6A 3'UTR       24284625//22608085 chr7:5108024-5108025(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr7:5108041-5108042(+) m6A 3'UTR       24284625//24981863//22608085 chr7:5108135-5108136(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr7:5108142-5108143(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr7:5108231-5108232(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr7:5108266-5108267(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr7:5108320-5108321(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr7:5108355-5108356(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:5108383-5108384(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:5108393-5108394(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:5108398-5108399(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:5108465-5108466(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:5108482-5108483(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:5108520-5108521(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:5108537-5108538(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:5108544-5108545(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr7:5108601-5108602(+) m6A 3'UTR       24284625//24981863//26404942//22575960//22608085 chr7:5108695-5108696(+) m6A 3'UTR       24284625//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-let-7g-3p	Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Serum     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cerebrospinal fluid     24797360 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	RBAK	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-let-7g-3p
Interactor2: RBAK

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.