Detail Information

Basic Information:


  VIRBase ID:  

HHID00065653

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:           LRIF1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7g-3p LRIF1
miRBase
Accession/Entrez ID		 MIMAT0004584 55791
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C1orf103//HBiX1//RIF1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7g-3p
rs1022640944 chr3:52268290    G/A
rs1166657040 chr3:52268299    A/G
rs1356748432 chr3:52268293    C/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LRIF1
chr1:111500085(-) A-I      intronic
chr1:111496995(-) A-I      intronic
chr1:111492166(-) A-I      intronic
chr1:111492299(-) A-I      intronic
chr1:111497102(-) A-I      intronic
chr1:111497006(-) A-I      intronic
chr1:111497031(-) A-I      intronic
chr1:111500041(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED LRIF1
chr1:111497006(-) A-G intron -    22484847
chr1:111500041(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LRIF1
chr1:111490565-111490566(-) m6A 3'UTR       24981863//27773535//22608085
chr1:111490649-111490650(-) m6A CDS       24284625//24981863//28052920//26404942//27773535//22608085
chr1:111490675-111490676(-) m6A CDS       24284625//24981863//28052920//26404942//27773535//22608085
chr1:111490745-111490746(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr1:111490813-111490814(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr1:111490826-111490827(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr1:111490831-111490832(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr1:111490954-111490955(-) m6A CDS       24284625//24981863//28052920//27773535//22608085
chr1:111490990-111490991(-) m6A CDS       24284625//24981863//28052920//27773535//27371828//22608085
chr1:111492475-111492476(-) m6A CDS       24981863//28052920//27773535//27371828//22608085
chr1:111492507-111492508(-) m6A CDS       24981863//28052920//27773535//27371828//22608085
chr1:111493915-111493916(-) m6A CDS//intron       27773535
chr1:111493922-111493923(-) m6A CDS//intron       27773535//22608085
chr1:111494050-111494051(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494094-111494095(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494104-111494105(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494126-111494127(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494158-111494159(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494229-111494230(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494313-111494314(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr1:111494324-111494325(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr1:111494391-111494392(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr1:111494547-111494548(-) m6A CDS//intron       24981863//27773535//22608085
chr1:111494679-111494680(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494749-111494750(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494762-111494763(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111494771-111494772(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111495029-111495030(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111495060-111495061(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111495073-111495074(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111495132-111495133(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr1:111495174-111495175(-) m6A 5'UTR//CDS//intron       24981863//22608085
chr1:111495191-111495192(-) m6A 5'UTR//CDS//intron       24981863//22608085
chr1:111495261-111495262(-) m6A 5'UTR//CDS//intron       24981863//27773535//22608085
chr1:111495283-111495284(-) m6A 5'UTR//CDS//intron       24981863//27773535
chr1:111506366-111506367(-) m6A 5'UTR       24284625//27773535
chr1:111506435-111506436(-) m6A 5'UTR       24284625//24981863//27773535
chr1:111506582-111506583(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7g-3p
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
LRIF1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7g-3p
Interactor2: LRIF1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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