Detail Information

Basic Information:


  VIRBase ID:  

HHID00065651

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:           AKIRIN2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-let-7g-3p AKIRIN2
miRBase
Accession/Entrez ID		 MIMAT0004584 55122
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C6orf166//dJ486L4.2//FBI1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-let-7g-3p
rs1022640944 chr3:52268290    G/A
rs1166657040 chr3:52268299    A/G
rs1356748432 chr3:52268293    C/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AKIRIN2
chr6:88389130(-) A-I      intronic
chr6:88389094(-) A-I      intronic
chr6:88389098(-) A-I      intronic
chr6:88389123(-) A-I      intronic
chr6:88398077(-) A-I      intronic
chr6:88398054(-) A-I      intronic
chr6:88390938(-) A-I      intronic
chr6:88398014(-) A-I      intronic
chr6:88397982(-) A-I      intronic
chr6:88397961(-) A-I      intronic
chr6:88397915(-) A-I      intronic
chr6:88392564(-) A-I      intronic
chr6:88390924(-) A-I      intronic
chr6:88390858(-) A-I      intronic
chr6:88390194(-) A-I      intronic
chr6:88390160(-) A-I      intronic
chr6:88398023(-) A-I      intronic
chr6:88390151(-) A-I      intronic
chr6:88390155(-) A-I      intronic
chr6:88390920(-) A-I      intronic
chr6:88397942(-) A-I      intronic
chr6:88390261(-) A-I      intronic
chr6:88398352(-) A-I      intronic
chr6:88388790(-) A-I      intronic
chr6:88400446(-) A-I      intronic
chr6:88398458(-) A-I      intronic
chr6:88392558(-) A-I      intronic
chr6:88392579(-) A-I      intronic
chr6:88397958(-) A-I      intronic
chr6:88402773(-) A-I      intronic
chr6:88388770(-) A-I      intronic
chr6:88398140(-) A-I      intronic
chr6:88398123(-) A-I      intronic
chr6:88389114(-) A-I      intronic
chr6:88389076(-) A-I      intronic
chr6:88393596(-) A-I      intronic
chr6:88397788(-) A-I      intronic
chr6:88398424(-) A-I      intronic
chr6:88397946(-) A-I      intronic
chr6:88406978(-) A-I      intronic
chr6:88389178(-) A-I      intronic
chr6:88390894(-) A-I      intronic
chr6:88391055(-) A-I      intronic
chr6:88392591(-) A-I      intronic
chr6:88389180(-) A-I      intronic
chr6:88398044(-) A-I      intronic
chr6:88389137(-) A-I      intronic
chr6:88390772(-) A-I      intronic
chr6:88398004(-) A-I      intronic
chr6:88393645(-) A-I      intronic
chr6:88388796(-) A-I      intronic
chr6:88398301(-) A-I      intronic
chr6:88398053(-) A-I      intronic
chr6:88398298(-) A-I      intronic
chr6:88388814(-) A-I      intronic
chr6:88388597(-) A-I      intronic
chr6:88397766(-) A-I      intronic
chr6:88398043(-) A-I      intronic
chr6:88393637(-) A-I      intronic
chr6:88398122(-) A-I      intronic
chr6:88398028(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED AKIRIN2
chr6:88389001(-) A-G intron -    22484847
chr6:88389180(-) A-G intron -    22484847
chr6:88390125(-) T-C intron -    22484847
chr6:88392554(-) T-C intron -    22484847
chr6:88392558(-) A-G intron -    22484847
chr6:88392591(-) A-G intron -    22484847
chr6:88393637(-) A-G intron -    22484847
chr6:88393645(-) A-G intron -    22484847
chr6:88397834(-) A-G intron -    22484847
chr6:88397942(-) A-G intron -    22484847
chr6:88397946(-) A-G intron -    22484847
chr6:88397958(-) A-G intron -    22484847
chr6:88398004(-) A-G intron -    22484847
chr6:88398043(-) A-G intron -    22484847
chr6:88398044(-) A-G intron -    22484847
chr6:88398053(-) A-G intron -    22484847
chr6:88398122(-) A-G intron -    22484847
chr6:88398123(-) A-G intron -    22484847
chr6:88398140(-) A-G intron -    22484847
chr6:88398298(-) A-G intron -    22484847
chr6:88398301(-) A-G intron -    22484847
chr6:88398352(-) A-G intron -    22484847
chr6:88398373(-) A-G intron -    22484847
chr6:88398424(-) A-G intron -    22484847
chr6:88398425(-) A-G intron -    22484847
chr6:88402773(-) A-G intron -    22484847
chr6:88403274(-) A-G intron -    22484847
chr6:88403275(-) C-T intron -    22484847
chr6:88406247(-) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AKIRIN2
chr6:88384818-88384819(-) m6A 3'UTR       22608085
chr6:88385590-88385591(-) m6A CDS       22575960
chr6:88387682-88387683(-) m6A CDS       27773535
chr6:88391350-88391351(-) m6A CDS       27773535
chr6:88391403-88391404(-) m6A CDS       24981863//27773535
chr6:88391428-88391429(-) m6A CDS       24981863//27773535
chr6:88391458-88391459(-) m6A CDS       24981863//27773535//22608085
chr6:88410293-88410294(-) m6A exon//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr6:88410309-88410310(-) m6A exon//intron       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr6:88410330-88410331(-) m6A exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:88410337-88410338(-) m6A exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:88410386-88410387(-) m6A exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:88410482-88410483(-) m6A exon//intron       24284625//24981863//28052920//27773535//27371828//22608085
chr6:88410499-88410500(-) m6A exon//intron       28052920//27773535//27371828//22608085
chr6:88411374-88411375(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536
chr6:88411667-88411668(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-let-7g-3p
Exosome Breast milk     22211110
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Serum     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
AKIRIN2
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-let-7g-3p
Interactor2: AKIRIN2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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