Basic Information:

  VIRBase ID:  

HHID00065633

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-let-7g-3p:  MIMAT0004584          ZBED4:  NM_014838     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-let-7g-3p	ZBED4
miRBase Accession/Entrez ID	MIMAT0004584	9889
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-let-7g-3p	rs1022640944 chr3:52268290    G/A rs1166657040 chr3:52268299    A/G rs1356748432 chr3:52268293    C/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZBED4	chr22:50264706(+) A-I      intronic chr22:50264688(+) A-I      intronic chr22:50264681(+) A-I      intronic chr22:50264663(+) A-I      intronic chr22:50264620(+) A-I      intronic chr22:50265027(+) A-I      intronic chr22:50271932(+) A-I      intronic chr22:50265014(+) A-I      intronic chr22:50253564(+) A-I      intronic chr22:50256489(+) A-I      intronic chr22:50255319(+) A-I      intronic chr22:50255267(+) A-I      intronic chr22:50264987(+) A-I      intronic chr22:50265003(+) A-I      intronic chr22:50265040(+) A-I      intronic chr22:50255052(+) A-I      intronic chr22:50255029(+) A-I      intronic chr22:50254987(+) A-I      intronic chr22:50253521(+) A-I      intronic chr22:50259598(+) A-I      intronic chr22:50253736(+) A-I      intronic chr22:50253755(+) A-I      intronic chr22:50253759(+) A-I      intronic chr22:50265047(+) A-I      intronic chr22:50253781(+) A-I      intronic chr22:50253816(+) A-I      intronic chr22:50254889(+) A-I      intronic chr22:50254955(+) A-I      intronic chr22:50256602(+) A-I      intronic chr22:50256612(+) A-I      intronic chr22:50259562(+) A-I      intronic chr22:50259588(+) A-I      intronic chr22:50259594(+) A-I      intronic chr22:50259595(+) A-I      intronic chr22:50264890(+) A-I      intronic chr22:50264948(+) A-I      intronic chr22:50275401(+) A-I      intronic chr22:50275370(+) A-I      intronic chr22:50275190(+) A-I      intronic chr22:50275113(+) A-I      intronic chr22:50275055(+) A-I      intronic chr22:50274882(+) A-I      intronic chr22:50274866(+) A-I      intronic chr22:50274798(+) A-I      intronic chr22:50274793(+) A-I      intronic chr22:50274765(+) A-I      intronic chr22:50256505(+) A-I      intronic chr22:50274740(+) A-I      intronic chr22:50272890(+) A-I      intronic chr22:50272686(+) A-I      intronic chr22:50272682(+) A-I      intronic chr22:50265119(+) A-I      intronic chr22:50272678(+) A-I      intronic chr22:50272582(+) A-I      intronic chr22:50272544(+) A-I      intronic chr22:50256449(+) A-I      intronic chr22:50264957(+) A-I      intronic chr22:50253412(+) A-I      intronic chr22:50274747(+) A-I      intronic chr22:50275095(+) A-I      intronic chr22:50266427(+) A-I      intronic chr22:50253840(+) A-I      intronic chr22:50265653(+) A-I      intronic chr22:50255307(+) A-I      intronic chr22:50255211(+) A-I      intronic chr22:50271698(+) A-I      intronic chr22:50271791(+) A-I      intronic chr22:50266527(+) A-I      intronic chr22:50253483(+) A-I      intronic chr22:50253544(+) A-I      intronic chr22:50258207(+) A-I      intronic chr22:50275239(+) A-I      intronic chr22:50265472(+) A-I      intronic chr22:50272837(+) A-I      intronic chr22:50275216(+) A-I      intronic chr22:50273049(+) A-I      intronic chr22:50272955(+) A-I      intronic chr22:50272977(+) A-I      intronic chr22:50264689(+) A-I      intronic chr22:50262120(+) A-I      intronic chr22:50265023(+) A-I      intronic chr22:50272538(+) A-I      intronic chr22:50271794(+) A-I      intronic chr22:50274926(+) A-I      intronic chr22:50262687(+) A-I      intronic chr22:50257154(+) A-I      intronic chr22:50266530(+) A-I      intronic chr22:50266551(+) A-I      intronic chr22:50258408(+) A-I      intronic chr22:50253568(+) A-I      intronic chr22:50272847(+) A-I      intronic chr22:50253912(+) A-I      intronic chr22:50275178(+) A-I      intronic chr22:50256947(+) A-I      intronic chr22:50273027(+) A-I      intronic chr22:50275111(+) A-I      intronic chr22:50262489(+) A-I      intronic chr22:50255290(+) A-I      intronic chr22:50265072(+) A-I      intronic chr22:50265054(+) A-I      intronic chr22:50266453(+) A-I      intronic chr22:50254919(+) A-I      intronic chr22:50275445(+) A-I      intronic chr22:50257181(+) A-I      intronic chr22:50253891(+) A-I      intronic chr22:50274943(+) A-I      intronic chr22:50275448(+) A-I      intronic chr22:50257225(+) A-I      intronic chr22:50262116(+) A-I      intronic chr22:50251320(+) A-I      intronic chr22:50255105(+) A-I      intronic chr22:50256405(+) A-I      intronic chr22:50272615(+) A-I      intronic chr22:50272646(+) A-I      intronic chr22:50264718(+) A-I      intronic chr22:50265078(+) A-I      intronic chr22:50274876(+) A-I      intronic chr22:50272537(+) A-I      intronic chr22:50274877(+) A-I      intronic chr22:50258209(+) A-I      intronic chr22:50255208(+) A-I      intronic chr22:50273004(+) A-I      intronic chr22:50251789(+) A-I      intronic chr22:50271892(+) A-I      intronic chr22:50275442(+) A-I      intronic chr22:50265053(+) A-I      intronic chr22:50272899(+) A-I      intronic chr22:50265115(+) A-I      intronic chr22:50275454(+) A-I      intronic chr22:50274739(+) A-I      intronic chr22:50255026(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZBED4	chr22:50275239(+) A-I intron -    22327324

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZBED4	chr22:50247552-50247553(+) m6A 5'UTR       24209618 chr22:50277040-50277041(+) m6A 5'UTR       24284625//24209618 chr22:50277100-50277101(+) m6A 5'UTR       24284625//24209618//24981863//22608085 chr22:50277131-50277132(+) m6A 5'UTR       24284625//24981863//26404942//22608085 chr22:50277189-50277190(+) m6A 5'UTR       24284625//24981863//26404942//27773535//22608085 chr22:50277276-50277277(+) m6A 5'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr22:50277328-50277329(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr22:50277431-50277432(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr22:50277452-50277453(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr22:50277463-50277464(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr22:50277641-50277642(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr22:50277698-50277699(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50277761-50277762(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:50277930-50277931(+) m6A CDS       24284625 chr22:50278104-50278105(+) m6A CDS       24284625 chr22:50278115-50278116(+) m6A CDS       24284625 chr22:50278208-50278209(+) m6A CDS       24284625//24981863 chr22:50278271-50278272(+) m6A CDS       24284625//24981863//22608085 chr22:50278496-50278497(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:50278514-50278515(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:50278677-50278678(+) m6A CDS       24284625//25456834//22608085 chr22:50278721-50278722(+) m6A CDS       24284625//25456834//22608085 chr22:50278806-50278807(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50278874-50278875(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50278952-50278953(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr22:50278987-50278988(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr22:50279027-50279028(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50279062-50279063(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50279115-50279116(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50279149-50279150(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50279186-50279187(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50279339-50279340(+) m6A CDS       24284625//24209618//24981863//22608085 chr22:50279376-50279377(+) m6A CDS       24284625//24209618//24981863//22608085 chr22:50279416-50279417(+) m6A CDS       24284625//24209618//24981863//22608085 chr22:50279527-50279528(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:50279636-50279637(+) m6A CDS       24284625//25456834//24981863//22575960//22608085 chr22:50279807-50279808(+) m6A CDS       24284625//24981863//22608085 chr22:50279852-50279853(+) m6A CDS       24284625//22608085 chr22:50279916-50279917(+) m6A CDS       24284625 chr22:50280387-50280388(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:50280405-50280406(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:50280411-50280412(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr22:50280479-50280480(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280497-50280498(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280533-50280534(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280594-50280595(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280623-50280624(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280765-50280766(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280777-50280778(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280827-50280828(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50280928-50280929(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr22:50281154-50281155(+) m6A 3'UTR       24981863 chr22:50281194-50281195(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr22:50281411-50281412(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr22:50281442-50281443(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr22:50281609-50281610(+) m6A 3'UTR       24284625//24209618//22608085 chr22:50283309-50283310(+) m6A 3'UTR       24981863 chr22:50283321-50283322(+) m6A 3'UTR       24981863 chr22:50283340-50283341(+) m6A 3'UTR       24981863//22608085 chr22:50283384-50283385(+) m6A 3'UTR       24981863//22608085 chr22:50283436-50283437(+) m6A 3'UTR       24284625//24981863//22608085 chr22:50283611-50283612(+) m6A 3'UTR       24981863 chr22:50283655-50283656(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-let-7g-3p	Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Serum     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cerebrospinal fluid     24797360 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells     -
	ZBED4	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-let-7g-3p
Interactor2: ZBED4

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.