Detail Information

Basic Information:


  VIRBase ID:  

HHID00065586

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-223-5p:           DNAJB14:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-223-5p DNAJB14
miRBase
Accession/Entrez ID		 MIMAT0004570 79982
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - EGNR9427//PRO34683

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-223-5p
rs1240009384 chrX:66018913    A/T
rs1397275461 chrX:66018904    G/T
rs1464475149 chrX:66018916    T/C
rs761701581 chrX:66018906    C/G
rs772305537 chrX:66018909    G/A
rs774279244 chrX:66018895    C/T
rs890919635 chrX:66018896    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DNAJB14
chr4:100844952(-) A-I      ncRNA
chr4:100837404(-) A-I      intronic
chr4:100833878(-) A-I      intronic
chr4:100833774(-) A-I      intronic
chr4:100854573(-) A-I      intronic
chr4:100854541(-) A-I      intronic
chr4:100840574(-) A-I      intronic
chr4:100840695(-) A-I      intronic
chr4:100840658(-) A-I      intronic
chr4:100860419(-) A-I      intronic
chr4:100860450(-) A-I      intronic
chr4:100861696(-) A-I      intronic
chr4:100860462(-) A-I      intronic
chr4:100840560(-) A-I      intronic
chr4:100840516(-) A-I      intronic
chr4:100838216(-) A-I      intronic
chr4:100838210(-) A-I      intronic
chr4:100838205(-) A-I      intronic
chr4:100838180(-) A-I      intronic
chr4:100861490(-) A-I      intronic
chr4:100837507(-) A-I      intronic
chr4:100860475(-) A-I      intronic
chr4:100837484(-) A-I      intronic
chr4:100860437(-) A-I      intronic
chr4:100837471(-) A-I      intronic
chr4:100837463(-) A-I      intronic
chr4:100858352(-) A-I      intronic
chr4:100860274(-) A-I      intronic
chr4:100858417(-) A-I      intronic
chr4:100858374(-) A-I      intronic
chr4:100858349(-) A-I      intronic
chr4:100858334(-) A-I      intronic
chr4:100858303(-) A-I      intronic
chr4:100858300(-) A-I      intronic
chr4:100858275(-) A-I      intronic
chr4:100857059(-) A-I      intronic
chr4:100838168(-) A-I      intronic
chr4:100865869(-) A-I      intronic
chr4:100838118(-) A-I      intronic
chr4:100837468(-) A-I      intronic
chr4:100840507(-) A-I      intronic
chr4:100837433(-) A-I      intronic
chr4:100865820(-) A-I      intronic
chr4:100833739(-) A-I      intronic
chr4:100838209(-) A-I      intronic
chr4:100861633(-) A-I      intronic
chr4:100840620(-) A-I      intronic
chr4:100833712(-) A-I      intronic
chr4:100854659(-) A-I      intronic
chr4:100836528(-) A-I      intronic
chr4:100837503(-) A-I      intronic
chr4:100858797(-) A-I      intronic
chr4:100837464(-) A-I      intronic
chr4:100837572(-) A-I      intronic
chr4:100838127(-) A-I      intronic
chr4:100838124(-) A-I      intronic
chr4:100857103(-) A-I      intronic
chr4:100833908(-) A-I      intronic
chr4:100840655(-) A-I      intronic
chr4:100838057(-) A-I      intronic
chr4:100838192(-) A-I      intronic
chr4:100838229(-) A-I      intronic
chr4:100837447(-) A-I      intronic
chr4:100854587(-) A-I      intronic
chr4:100838047(-) A-I      intronic
chr4:100837398(-) A-I      intronic
chr4:100837334(-) A-I      intronic
chr4:100833829(-) A-I      intronic
chr4:100858306(-) A-I      intronic
chr4:100833775(-) A-I      intronic
chr4:100840654(-) A-I      intronic
chr4:100854614(-) A-I      intronic
chr4:100837466(-) A-I      intronic
chr4:100838173(-) A-I      intronic
chr4:100833713(-) A-I      intronic
chr4:100861637(-) A-I      intronic
chr4:100836566(-) A-I      intronic
chr4:100857021(-) A-I      intronic
chr4:100861765(-) A-I      intronic
chr4:100837532(-) A-I      intronic
chr4:100854727(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DNAJB14
chr4:100837398(-) A-I intron -    22327324
chr4:100837447(-) A-I intron -    22327324
chr4:100837503(-) A-I intron -    22327324
chr4:100837572(-) A-I intron -    21960545
chr4:100833712(-) A-G intron -    22484847
chr4:100833713(-) A-G intron -    22484847
chr4:100833739(-) A-G intron -    22484847
chr4:100833749(-) T-C intron -    22484847
chr4:100833829(-) A-G intron -    22484847
chr4:100833903(-) A-G intron -    22484847
chr4:100833908(-) A-G intron -    22484847
chr4:100837398(-) A-G intron -    22484847
chr4:100837424(-) A-G intron -    22484847
chr4:100837428(-) A-G intron -    22484847
chr4:100837433(-) A-G intron -    22484847
chr4:100837447(-) A-G intron -    22484847
chr4:100837464(-) A-G intron -    22484847
chr4:100837465(-) A-G intron -    22484847
chr4:100837503(-) A-G intron -    22484847
chr4:100837572(-) A-G intron -    22484847
chr4:100838048(-) A-G intron -    22484847
chr4:100838057(-) A-G intron -    22484847
chr4:100838118(-) A-G intron -    22484847
chr4:100838124(-) A-G intron -    22484847
chr4:100838127(-) A-G intron -    22484847
chr4:100838168(-) A-G intron -    22484847
chr4:100838170(-) A-G intron -    22484847
chr4:100838173(-) A-G intron -    22484847
chr4:100838209(-) A-G intron -    22484847
chr4:100838229(-) A-G intron -    22484847
chr4:100838245(-) A-G intron -    22484847
chr4:100840507(-) A-G intron -    22484847
chr4:100854659(-) A-G intron -    22484847
chr4:100857021(-) A-G intron -    22484847
chr4:100858284(-) A-G intron -    22484847
chr4:100858306(-) A-G intron -    22484847
chr4:100858445(-) G-A intron -    22484847
chr4:100861633(-) A-G intron -    22484847
chr4:100865869(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DNAJB14
chr4:100822009-100822010(-) m6A 3'UTR//exon       27773535//22608085
chr4:100822050-100822051(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr4:100822078-100822079(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr4:100822083-100822084(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr4:100822183-100822184(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr4:100822233-100822234(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085
chr4:100822306-100822307(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535//22608085
chr4:100824889-100824890(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535//22608085
chr4:100824989-100824990(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr4:100825019-100825020(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr4:100825026-100825027(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr4:100825041-100825042(-) m6A 3'UTR//CDS//exon       24981863//27773535//22608085
chr4:100825050-100825051(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr4:100827700-100827701(-) m6A 3'UTR//CDS//exon       27773535
chr4:100829905-100829906(-) m6A 3'UTR//CDS//exon       27773535
chr4:100829959-100829960(-) m6A 3'UTR//CDS//exon       27773535
chr4:100829979-100829980(-) m6A 3'UTR//CDS//exon       27773535
chr4:100830006-100830007(-) m6A 3'UTR//CDS//exon       27773535
chr4:100851716-100851717(-) m6A CDS//exon//intron       27371828
chr4:100867717-100867718(-) m6A CDS//exon       25456834//24981863//27371828//27773536
chr4:100867739-100867740(-) m1A 5'UTR//exon       26863196//26863410

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-223-5p
Exosome Primary dendritic cells     21505438
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
DNAJB14
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-223-5p
Interactor2: DNAJB14

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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