Detail Information

Basic Information:


  VIRBase ID:  

HHID00065577

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-223-5p:           SNX16:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-223-5p SNX16
miRBase
Accession/Entrez ID		 MIMAT0004570 64089
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-223-5p
rs1240009384 chrX:66018913    A/T
rs1397275461 chrX:66018904    G/T
rs1464475149 chrX:66018916    T/C
rs761701581 chrX:66018906    C/G
rs772305537 chrX:66018909    G/A
rs774279244 chrX:66018895    C/T
rs890919635 chrX:66018896    G/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SNX16
chr8:82711915-82711916(-) m6A 3'UTR       27773535
chr8:82713419-82713420(-) m6A 3'UTR       27773535
chr8:82713640-82713641(-) m6A 3'UTR       24981863//27773535//22608085
chr8:82713648-82713649(-) m6A 3'UTR       24981863//27773535//22608085
chr8:82713655-82713656(-) m6A 3'UTR       24981863//27773535//22608085
chr8:82713702-82713703(-) m6A 3'UTR       27773535//22608085
chr8:82713735-82713736(-) m6A CDS       27773535
chr8:82751903-82751904(-) m6A CDS       24981863//22608085
chr8:82751923-82751924(-) m6A CDS       24981863//22608085
chr8:82751936-82751937(-) m6A CDS       24981863//22608085
chr8:82751946-82751947(-) m6A CDS       24981863//22608085
chr8:82751954-82751955(-) m6A CDS       24981863//22608085
chr8:82751998-82751999(-) m6A CDS//intron       24209618//24981863//22608085
chr8:82752058-82752059(-) m6A CDS//intron       24209618//24981863//22608085
chr8:82752062-82752063(-) m6A CDS//intron       -
chr8:82752084-82752085(-) m6A CDS       -
chr8:82752156-82752157(-) m6A CDS       24284625//27773535//22608085
chr8:82752180-82752181(-) m6A CDS       24284625//27773535//22608085
chr8:82752260-82752261(-) m6A 5'UTR       24284625//24981863//27773535//22608085
chr8:82752454-82752455(-) m6A 5'UTR//intron       24981863//27773535//22608085
chr8:82754052-82754053(-) m6A 5'UTR//intron       -
chr8:82754079-82754080(-) m6A 5'UTR//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-223-5p
Exosome Primary dendritic cells     21505438
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SNX16
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-223-5p
Interactor2: SNX16

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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