Basic Information:

  VIRBase ID:  

HHID00065571

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-223-5p:  MIMAT0004570          C1GALT1:  NM_020156     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-223-5p	C1GALT1
miRBase Accession/Entrez ID	MIMAT0004570	56913
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C1GALT//T-synthase

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-223-5p	rs1240009384 chrX:66018913    A/T rs1397275461 chrX:66018904    G/T rs1464475149 chrX:66018916    T/C rs761701581 chrX:66018906    C/G rs772305537 chrX:66018909    G/A rs774279244 chrX:66018895    C/T rs890919635 chrX:66018896    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	C1GALT1	chr7:7223331(+) A-I      intronic chr7:7232364(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	C1GALT1	chr7:7285819(+) A-I intron -    21960545 chr7:7260341(+) T-C intron -    22484847 chr7:7263053(+) G-C intron -    22484847 chr7:7272129(+) T-G intron -    22484847 chr7:7272309(+) T-C intron -    22484847 chr7:7272902(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	C1GALT1	chr7:7274114-7274115(+) m6A CDS//exon       22608085 chr7:7274132-7274133(+) m6A CDS//exon       22608085 chr7:7274140-7274141(+) m6A CDS//exon       22608085 chr7:7274196-7274197(+) m6A exon//intron       22608085 chr7:7277891-7277892(+) m6A CDS       24284625//24981863//22608085 chr7:7277897-7277898(+) m6A CDS       24284625//24209618//24981863//22608085 chr7:7277909-7277910(+) m6A CDS       24284625//24209618//24981863//22608085 chr7:7277960-7277961(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr7:7277979-7277980(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr7:7278042-7278043(+) Y CDS       26075521 chr7:7278047-7278048(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278063-7278064(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278070-7278071(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:7278103-7278104(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:7278132-7278133(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr7:7278194-7278195(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278234-7278235(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278349-7278350(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278383-7278384(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278457-7278458(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:7278480-7278481(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr7:7278590-7278591(+) m6A CDS//intron       22608085 chr7:7283317-7283318(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr7:7283375-7283376(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:7283411-7283412(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:7283433-7283434(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:7283465-7283466(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:7283480-7283481(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr7:7283503-7283504(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:7283585-7283586(+) m6A 3'UTR       24981863//27773535//22608085 chr7:7283619-7283620(+) m6A 3'UTR       22608085 chr7:7286210-7286211(+) m6A 3'UTR       - chr7:7286232-7286233(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-223-5p	Exosome Primary dendritic cells     21505438 Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	C1GALT1	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-223-5p
Interactor2: C1GALT1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.