Detail Information

Basic Information:


  VIRBase ID:  

HHID00065544

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-223-5p:           TRAPPC8:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-223-5p TRAPPC8
miRBase
Accession/Entrez ID		 MIMAT0004570 22878
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GSG1//HsT2706//KIAA1012//TRS85

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-223-5p
rs1240009384 chrX:66018913    A/T
rs1397275461 chrX:66018904    G/T
rs1464475149 chrX:66018916    T/C
rs761701581 chrX:66018906    C/G
rs772305537 chrX:66018909    G/A
rs774279244 chrX:66018895    C/T
rs890919635 chrX:66018896    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TRAPPC8
chr18:29414255(-) A-I      intronic
chr18:29414248(-) A-I      intronic
chr18:29414245(-) A-I      intronic
chr18:29414244(-) A-I      intronic
chr18:29414238(-) A-I      intronic
chr18:29414237(-) A-I      intronic
chr18:29414234(-) A-I      intronic
chr18:29414202(-) A-I      intronic
chr18:29497923(-) A-I      intronic
chr18:29411202(-) A-I      intronic
chr18:29476711(-) A-I      intronic
chr18:29476715(-) A-I      intronic
chr18:29507916(-) A-I      intronic
chr18:29453151(-) A-I      intronic
chr18:29453149(-) A-I      intronic
chr18:29453148(-) A-I      intronic
chr18:29453104(-) A-I      intronic
chr18:29414268(-) A-I      intronic
chr18:29414266(-) A-I      intronic
chr18:29507334(-) A-I      intronic
chr18:29517344(-) A-I      intronic
chr18:29411262(-) A-I      intronic
chr18:29413773(-) A-I      intronic
chr18:29413782(-) A-I      intronic
chr18:29413798(-) A-I      intronic
chr18:29413878(-) A-I      intronic
chr18:29497961(-) A-I      intronic
chr18:29497830(-) A-I      intronic
chr18:29414198(-) A-I      intronic
chr18:29487196(-) A-I      intronic
chr18:29414281(-) A-I      intronic
chr18:29414340(-) A-I      intronic
chr18:29497965(-) A-I      intronic
chr18:29497967(-) A-I      intronic
chr18:29507144(-) A-I      intronic
chr18:29507875(-) A-I      intronic
chr18:29519710(-) A-I      intronic
chr18:29519699(-) A-I      intronic
chr18:29519690(-) A-I      intronic
chr18:29517946(-) A-I      intronic
chr18:29516647(-) A-I      intronic
chr18:29516423(-) A-I      intronic
chr18:29516230(-) A-I      intronic
chr18:29510691(-) A-I      intronic
chr18:29517842(-) A-I      intronic
chr18:29510302(-) A-I      intronic
chr18:29510301(-) A-I      intronic
chr18:29510277(-) A-I      intronic
chr18:29509572(-) A-I      intronic
chr18:29509483(-) A-I      intronic
chr18:29507913(-) A-I      intronic
chr18:29416853(-) A-I      intronic
chr18:29416863(-) A-I      intronic
chr18:29416930(-) A-I      intronic
chr18:29417006(-) A-I      intronic
chr18:29417439(-) A-I      intronic
chr18:29417578(-) A-I      intronic
chr18:29417585(-) A-I      intronic
chr18:29417598(-) A-I      intronic
chr18:29418044(-) A-I      intronic
chr18:29430187(-) A-I      intronic
chr18:29431587(-) A-I      intronic
chr18:29431615(-) A-I      intronic
chr18:29432085(-) A-I      intronic
chr18:29432086(-) A-I      intronic
chr18:29432099(-) A-I      intronic
chr18:29442825(-) A-I      intronic
chr18:29453077(-) A-I      intronic
chr18:29453078(-) A-I      intronic
chr18:29453105(-) A-I      intronic
chr18:29462718(-) A-I      intronic
chr18:29464805(-) A-I      intronic
chr18:29465000(-) A-I      intronic
chr18:29465001(-) A-I      intronic
chr18:29465577(-) A-I      intronic
chr18:29465578(-) A-I      intronic
chr18:29465630(-) A-I      intronic
chr18:29465747(-) A-I      intronic
chr18:29466080(-) A-I      intronic
chr18:29466106(-) A-I      intronic
chr18:29466173(-) A-I      intronic
chr18:29466199(-) A-I      intronic
chr18:29466230(-) A-I      intronic
chr18:29466741(-) A-I      intronic
chr18:29466751(-) A-I      intronic
chr18:29466761(-) A-I      intronic
chr18:29466778(-) A-I      intronic
chr18:29466781(-) A-I      intronic
chr18:29466857(-) A-I      intronic
chr18:29466898(-) A-I      intronic
chr18:29472864(-) A-I      intronic
chr18:29472871(-) A-I      intronic
chr18:29472872(-) A-I      intronic
chr18:29472898(-) A-I      intronic
chr18:29482178(-) A-I      intronic
chr18:29483744(-) A-I      intronic
chr18:29517365(-) A-I      intronic
chr18:29507873(-) A-I      intronic
chr18:29483745(-) A-I      intronic
chr18:29516693(-) A-I      intronic
chr18:29483771(-) A-I      intronic
chr18:29516756(-) A-I      intronic
chr18:29520316(-) A-I      intronic
chr18:29520585(-) A-I      intronic
chr18:29507492(-) A-I      intronic
chr18:29507419(-) A-I      intronic
chr18:29519718(-) A-I      intronic
chr18:29483772(-) A-I      intronic
chr18:29484296(-) A-I      intronic
chr18:29484390(-) A-I      intronic
chr18:29503835(-) A-I      intronic
chr18:29506470(-) A-I      intronic
chr18:29506600(-) A-I      intronic
chr18:29506617(-) A-I      intronic
chr18:29507143(-) A-I      intronic
chr18:29414276(-) A-I      intronic
chr18:29516743(-) A-I      intronic
chr18:29476859(-) A-I      intronic
chr18:29509260(-) A-I      intronic
chr18:29516177(-) A-I      intronic
chr18:29413710(-) A-I      intronic
chr18:29501414(-) A-I      intronic
chr18:29508075(-) A-I      intronic
chr18:29438993(-) A-I      intronic
chr18:29466752(-) A-I      intronic
chr18:29507621(-) A-I      intronic
chr18:29499333(-) A-I      intronic
chr18:29417490(-) A-I      intronic
chr18:29509615(-) A-I      intronic
chr18:29506505(-) A-I      intronic
chr18:29414352(-) A-I      intronic
chr18:29519742(-) A-I      intronic
chr18:29418011(-) A-I      intronic
chr18:29516789(-) A-I      intronic
chr18:29502407(-) A-I      intronic
chr18:29514829(-) A-I      intronic
chr18:29509484(-) A-I      intronic
chr18:29487219(-) A-I      intronic
chr18:29516170(-) A-I      intronic
chr18:29520328(-) A-I      intronic
chr18:29417512(-) A-I      intronic
chr18:29417617(-) A-I      intronic
chr18:29516668(-) A-I      intronic
chr18:29418077(-) A-I      intronic
chr18:29516779(-) A-I      intronic
chr18:29495561(-) A-I      intronic
chr18:29417473(-) A-I      intronic
chr18:29487192(-) A-I      intronic
chr18:29472771(-) A-I      intronic
chr18:29413837(-) A-I      intronic
chr18:29472796(-) A-I      intronic
chr18:29517484(-) A-I      intronic
chr18:29462744(-) A-I      intronic
chr18:29500567(-) A-I      intronic
chr18:29453119(-) A-I      intronic
chr18:29466861(-) A-I      intronic
chr18:29509457(-) A-I      intronic
chr18:29457386(-) A-I      intronic
chr18:29520626(-) A-I      intronic
chr18:29517937(-) A-I      intronic
chr18:29486075(-) A-I      intronic
chr18:29414277(-) A-I      intronic
chr18:29463901(-) A-I      intronic
chr18:29506572(-) A-I      intronic
chr18:29515863(-) A-I      intronic
chr18:29413707(-) A-I      intronic
chr18:29413777(-) A-I      intronic
chr18:29447838(-) A-I      intronic
chr18:29432046(-) A-I      intronic
chr18:29462779(-) A-I      intronic
chr18:29509374(-) A-I      intronic
chr18:29510787(-) A-I      intronic
chr18:29472880(-) A-I      intronic
chr18:29509577(-) A-I      intronic
chr18:29483818(-) A-I      intronic
chr18:29426416(-) A-I      intronic
chr18:29430142(-) A-I      intronic
chr18:29519828(-) A-I      intronic
chr18:29466822(-) A-I      intronic
chr18:29491645(-) A-I      intronic
chr18:29414161(-) A-I      intronic
chr18:29517805(-) A-I      intronic
chr18:29510191(-) A-I      intronic
chr18:29472942(-) A-I      intronic
chr18:29519696(-) A-I      intronic
chr18:29517276(-) A-I      intronic
chr18:29487237(-) A-I      intronic
chr18:29520564(-) A-I      intronic
chr18:29417476(-) A-I      intronic
chr18:29508373(-) A-I      intronic
chr18:29501405(-) A-I      intronic
chr18:29414170(-) A-I      intronic
chr18:29517870(-) A-I      intronic
chr18:29509323(-) A-I      intronic
chr18:29413908(-) A-I      intronic
chr18:29413853(-) A-I      intronic
chr18:29507861(-) A-I      intronic
chr18:29411132(-) A-I      intronic
chr18:29414140(-) A-I      intronic
chr18:29507647(-) A-I      intronic
chr18:29517763(-) A-I      intronic
chr18:29508205(-) A-I      intronic
chr18:29517831(-) A-I      intronic
chr18:29507501(-) A-I      intronic
chr18:29500600(-) A-I      intronic
chr18:29414208(-) A-I      intronic
chr18:29515185(-) A-I      intronic
chr18:29414100(-) A-I      intronic
chr18:29465784(-) A-I      intronic
chr18:29413721(-) A-I      intronic
chr18:29516813(-) A-I      intronic
chr18:29517758(-) A-I      intronic
chr18:29510220(-) A-I      intronic
chr18:29417550(-) A-I      intronic
chr18:29516753(-) A-I      intronic
chr18:29484267(-) A-I      intronic
chr18:29438970(-) A-I      intronic
chr18:29516778(-) A-I      intronic
chr18:29487213(-) A-I      intronic
chr18:29515448(-) A-I      intronic
chr18:29517835(-) A-I      intronic
chr18:29486219(-) A-I      intronic
chr18:29413902(-) A-I      intronic
chr18:29520334(-) A-I      intronic
chr18:29507354(-) A-I      intronic
chr18:29426421(-) A-I      intronic
chr18:29496691(-) A-I      intronic
chr18:29414207(-) A-I      intronic
chr18:29465639(-) A-I      intronic
chr18:29515905(-) A-I      intronic
chr18:29416726(-) A-I      intronic
chr18:29417464(-) A-I      intronic
chr18:29413843(-) A-I      intronic
chr18:29452479(-) A-I      intronic
chr18:29516699(-) A-I      intronic
chr18:29516608(-) A-I      intronic
chr18:29508468(-) A-I      intronic
chr18:29520644(-) A-I      intronic
chr18:29462740(-) A-I      intronic
chr18:29413846(-) A-I      intronic
chr18:29413852(-) A-I      intronic
chr18:29417540(-) A-I      intronic
chr18:29472744(-) A-I      intronic
chr18:29508408(-) A-I      intronic
chr18:29418071(-) A-I      intronic
chr18:29515761(-) A-I      intronic
chr18:29515972(-) A-I      intronic
chr18:29517734(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TRAPPC8
chr18:29414207(-) A-I intron -    22327324
chr18:29413777(-) A-G intron -    22484847
chr18:29413846(-) A-G intron -    22484847
chr18:29413852(-) A-G intron -    22484847
chr18:29414207(-) A-G intron -    22484847
chr18:29414277(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TRAPPC8
chr18:29409205-29409206(-) m6A 3'UTR       27773535
chr18:29409214-29409215(-) m6A 3'UTR       27773535
chr18:29409237-29409238(-) m6A 3'UTR       27773535
chr18:29409249-29409250(-) m6A 3'UTR       27773535
chr18:29409274-29409275(-) m6A 3'UTR       27773535
chr18:29409317-29409318(-) m6A 3'UTR       27773535
chr18:29409535-29409536(-) m6A 3'UTR       25456834
chr18:29409548-29409549(-) m6A 3'UTR       25456834
chr18:29409562-29409563(-) m6A 3'UTR       25456834
chr18:29409575-29409576(-) m6A 3'UTR       25456834
chr18:29409604-29409605(-) m6A 3'UTR       25456834
chr18:29409735-29409736(-) m6A 3'UTR       25456834
chr18:29409918-29409919(-) m6A 3'UTR       27773535
chr18:29410439-29410440(-) m6A 3'UTR       27773535
chr18:29410517-29410518(-) m6A 3'UTR//exon       27773535//22608085
chr18:29410556-29410557(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr18:29410767-29410768(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr18:29410787-29410788(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr18:29410815-29410816(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//27371828//22608085
chr18:29410894-29410895(-) m6A 3'UTR//CDS//exon       24981863//22608085
chr18:29410909-29410910(-) m6A 3'UTR//CDS//exon       22608085
chr18:29432618-29432619(-) m6A 3'UTR//CDS//exon       27773535
chr18:29432656-29432657(-) m6A exon//intron       27773535
chr18:29432664-29432665(-) m6A exon//intron       27773535
chr18:29437682-29437683(-) m6A CDS       24284625//24981863//22608085
chr18:29437743-29437744(-) m6A CDS//intron       24284625//24981863//22608085
chr18:29519391-29519392(-) m6A CDS//exon//intron       27773535
chr18:29519440-29519441(-) m6A exon//intron       27773535
chr18:29519451-29519452(-) m6A exon//intron       27773535
chr18:29522891-29522892(-) m6A 5'UTR//exon//intron       24209618//25456834//27371828//27773536//22608085
chr18:29523007-29523008(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-223-5p
Exosome Primary dendritic cells     21505438
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
TRAPPC8
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-223-5p
Interactor2: TRAPPC8

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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