Basic Information:

  VIRBase ID:  

HHID00065511

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-223-5p:  MIMAT0004570          GOLGA1:  NM_002077     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-223-5p	GOLGA1
miRBase Accession/Entrez ID	MIMAT0004570	2800
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	golgin-97

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-223-5p	rs1240009384 chrX:66018913    A/T rs1397275461 chrX:66018904    G/T rs1464475149 chrX:66018916    T/C rs761701581 chrX:66018906    C/G rs772305537 chrX:66018909    G/A rs774279244 chrX:66018895    C/T rs890919635 chrX:66018896    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GOLGA1	chr9:127672540(-) A-I      intronic chr9:127672545(-) A-I      intronic chr9:127672563(-) A-I      intronic chr9:127674879(-) A-I      intronic chr9:127674914(-) A-I      intronic chr9:127674960(-) A-I      intronic chr9:127675077(-) A-I      intronic chr9:127678059(-) A-I      intronic chr9:127678138(-) A-I      intronic chr9:127678269(-) A-I      intronic chr9:127678298(-) A-I      intronic chr9:127678305(-) A-I      intronic chr9:127680166(-) A-I      intronic chr9:127666135(-) A-I      intronic chr9:127666125(-) A-I      intronic chr9:127680224(-) A-I      intronic chr9:127680228(-) A-I      intronic chr9:127680229(-) A-I      intronic chr9:127680326(-) A-I      intronic chr9:127680328(-) A-I      intronic chr9:127680347(-) A-I      intronic chr9:127680368(-) A-I      intronic chr9:127680377(-) A-I      intronic chr9:127680412(-) A-I      intronic chr9:127680851(-) A-I      intronic chr9:127680949(-) A-I      intronic chr9:127680988(-) A-I      intronic chr9:127681049(-) A-I      intronic chr9:127684596(-) A-I      intronic chr9:127684803(-) A-I      intronic chr9:127686259(-) A-I      intronic chr9:127686402(-) A-I      intronic chr9:127687231(-) A-I      intronic chr9:127687237(-) A-I      intronic chr9:127687247(-) A-I      intronic chr9:127687815(-) A-I      intronic chr9:127697107(-) A-I      intronic chr9:127698962(-) A-I      intronic chr9:127686303(-) A-I      intronic chr9:127686304(-) A-I      intronic chr9:127701970(-) A-I      intronic chr9:127701979(-) A-I      intronic chr9:127701996(-) A-I      intronic chr9:127702014(-) A-I      intronic chr9:127702018(-) A-I      intronic chr9:127702020(-) A-I      intronic chr9:127702023(-) A-I      intronic chr9:127659049(-) A-I      intronic chr9:127666247(-) A-I      intronic chr9:127666242(-) A-I      intronic chr9:127664963(-) A-I      intronic chr9:127664946(-) A-I      intronic chr9:127664943(-) A-I      intronic chr9:127663586(-) A-I      intronic chr9:127663389(-) A-I      intronic chr9:127663343(-) A-I      intronic chr9:127659159(-) A-I      intronic chr9:127659143(-) A-I      intronic chr9:127659142(-) A-I      intronic chr9:127659125(-) A-I      intronic chr9:127659095(-) A-I      intronic chr9:127656768(-) A-I      intronic chr9:127655128(-) A-I      intronic chr9:127654453(-) A-I      intronic chr9:127654371(-) A-I      intronic chr9:127654362(-) A-I      intronic chr9:127647457(-) A-I      intronic chr9:127647364(-) A-I      intronic chr9:127646383(-) A-I      intronic chr9:127645891(-) A-I      intronic chr9:127645871(-) A-I      intronic chr9:127645868(-) A-I      intronic chr9:127645855(-) A-I      intronic chr9:127645703(-) A-I      intronic chr9:127645637(-) A-I      intronic chr9:127645625(-) A-I      intronic chr9:127645599(-) A-I      intronic chr9:127666255(-) A-I      intronic chr9:127671414(-) A-I      intronic chr9:127671470(-) A-I      intronic chr9:127671577(-) A-I      intronic chr9:127671719(-) A-I      intronic chr9:127671804(-) A-I      intronic chr9:127671805(-) A-I      intronic chr9:127672181(-) A-I      intronic chr9:127672277(-) A-I      intronic chr9:127672348(-) A-I      intronic chr9:127672385(-) A-I      intronic chr9:127672483(-) A-I      intronic chr9:127646470(-) A-I      intronic chr9:127655001(-) A-I      intronic chr9:127686299(-) A-I      intronic chr9:127699002(-) A-I      intronic chr9:127674986(-) A-I      intronic chr9:127659760(-) A-I      intronic chr9:127646469(-) A-I      intronic chr9:127647311(-) A-I      intronic chr9:127672168(-) A-I      intronic chr9:127659757(-) A-I      intronic chr9:127695791(-) A-I      intronic chr9:127680825(-) A-I      intronic chr9:127687914(-) A-I      intronic chr9:127682634(-) A-I      intronic chr9:127671354(-) A-I      intronic chr9:127681271(-) A-I      intronic chr9:127681306(-) A-I      intronic chr9:127645816(-) A-I      intronic chr9:127675005(-) A-I      intronic chr9:127647308(-) A-I      intronic chr9:127659135(-) A-I      intronic chr9:127672158(-) A-I      intronic chr9:127682376(-) A-I      intronic chr9:127659692(-) A-I      intronic chr9:127682497(-) A-I      intronic chr9:127646563(-) A-I      intronic chr9:127687831(-) A-I      intronic chr9:127698981(-) A-I      intronic chr9:127655046(-) A-I      intronic chr9:127646564(-) A-I      intronic chr9:127695966(-) A-I      intronic chr9:127698788(-) A-I      intronic chr9:127647663(-) A-I      intronic chr9:127682368(-) A-I      intronic chr9:127665522(-) A-I      intronic chr9:127666266(-) A-I      intronic chr9:127659686(-) A-I      intronic chr9:127686186(-) A-I      intronic chr9:127655309(-) A-I      intronic chr9:127658964(-) A-I      intronic chr9:127681460(-) A-I      intronic chr9:127647682(-) A-I      intronic chr9:127686267(-) A-I      intronic chr9:127647504(-) A-I      intronic chr9:127654955(-) A-I      intronic chr9:127682651(-) A-I      intronic chr9:127697274(-) A-I      intronic chr9:127675024(-) A-I      intronic chr9:127647233(-) A-I      intronic chr9:127682667(-) A-I      intronic chr9:127659784(-) A-I      intronic chr9:127665658(-) A-I      intronic chr9:127658606(-) A-I      intronic chr9:127645451(-) A-I      intronic chr9:127682629(-) A-I      intronic chr9:127686232(-) A-I      intronic chr9:127686914(-) A-I      intronic chr9:127675094(-) A-I      intronic chr9:127682563(-) A-I      intronic chr9:127680959(-) A-I      intronic chr9:127647642(-) A-I      intronic chr9:127645904(-) A-I      intronic chr9:127687941(-) A-I      intronic chr9:127664663(-) A-I      intronic chr9:127680301(-) A-I      intronic chr9:127654483(-) A-I      intronic chr9:127697060(-) A-I      intronic chr9:127666179(-) A-I      intronic chr9:127666295(-) A-I      intronic chr9:127680204(-) A-I      intronic chr9:127681293(-) A-I      intronic chr9:127675093(-) A-I      intronic chr9:127671491(-) A-I      intronic chr9:127682559(-) A-I      intronic chr9:127647652(-) A-I      intronic chr9:127646321(-) A-I      intronic chr9:127686207(-) A-I      intronic chr9:127646358(-) A-I      intronic chr9:127681412(-) A-I      intronic chr9:127658571(-) A-I      intronic chr9:127654457(-) A-I      intronic chr9:127646376(-) A-I      intronic chr9:127681414(-) A-I      intronic chr9:127654388(-) A-I      intronic chr9:127659799(-) A-I      intronic chr9:127682377(-) A-I      intronic chr9:127682566(-) A-I      intronic chr9:127664664(-) A-I      intronic chr9:127659003(-) A-I      intronic chr9:127645544(-) A-I      intronic chr9:127681441(-) A-I      intronic chr9:127647351(-) A-I      intronic chr9:127666165(-) A-I      intronic chr9:127686255(-) A-I      intronic chr9:127647232(-) A-I      intronic chr9:127699810(-) A-I      intronic chr9:127645702(-) A-I      intronic chr9:127663375(-) A-I      intronic chr9:127654203(-) A-I      intronic chr9:127659720(-) A-I      intronic chr9:127647523(-) A-I      intronic chr9:127645864(-) A-I      intronic chr9:127658976(-) A-I      intronic chr9:127666180(-) A-I      intronic chr9:127647655(-) A-I      intronic chr9:127645819(-) A-I      intronic chr9:127686685(-) A-I      intronic chr9:127659128(-) A-I      intronic chr9:127656699(-) A-I      intronic chr9:127663889(-) A-I      intronic chr9:127659099(-) A-I      intronic chr9:127686717(-) A-I      intronic chr9:127681310(-) A-I      intronic chr9:127666170(-) A-I      intronic chr9:127654204(-) A-I      intronic chr9:127698866(-) A-I      intronic chr9:127647664(-) A-I      intronic chr9:127646541(-) A-I      intronic chr9:127686273(-) A-I      intronic chr9:127659053(-) A-I      intronic chr9:127666316(-) A-I      intronic chr9:127680404(-) A-I      intronic chr9:127646468(-) A-I      intronic chr9:127647681(-) A-I      intronic chr9:127680270(-) A-I      intronic chr9:127645768(-) A-I      intronic chr9:127664565(-) A-I      intronic chr9:127647762(-) A-I      intronic chr9:127698841(-) A-I      intronic chr9:127686231(-) A-I      intronic chr9:127678132(-) A-I      intronic chr9:127685688(-) A-I      intronic chr9:127659124(-) A-I      intronic chr9:127685683(-) A-I      intronic chr9:127655371(-) A-I      intronic chr9:127647220(-) A-I      intronic chr9:127653313(-) A-I      intronic chr9:127699003(-) A-I      intronic chr9:127684944(-) A-I      intronic chr9:127653323(-) A-I      intronic chr9:127697264(-) A-I      intronic chr9:127663430(-) A-I      intronic chr9:127681532(-) A-I      intronic chr9:127687739(-) A-I      intronic chr9:127687832(-) A-I      intronic chr9:127658666(-) A-I      intronic chr9:127659878(-) A-I      intronic chr9:127654990(-) A-I      intronic chr9:127665541(-) A-I      intronic chr9:127687745(-) A-I      intronic chr9:127659102(-) A-I      intronic chr9:127645920(-) A-I      intronic chr9:127665521(-) A-I      intronic chr9:127663425(-) A-I      intronic chr9:127680940(-) A-I      intronic chr9:127686787(-) A-I      intronic chr9:127646533(-) A-I      intronic chr9:127647640(-) A-I      intronic chr9:127681345(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	GOLGA1	chr9:127647861(-) C-T intron -    22484847 chr9:127645819(-) A-G intron -    22484847 chr9:127645864(-) A-G intron -    22484847 chr9:127654457(-) A-G intron -    22484847 chr9:127659686(-) A-G intron -    22484847 chr9:127659692(-) A-G intron -    22484847 chr9:127659760(-) A-G intron -    22484847 chr9:127663375(-) A-G intron -    22484847 chr9:127663430(-) A-G intron -    22484847 chr9:127665521(-) A-G intron -    22484847 chr9:127665541(-) A-G intron -    22484847 chr9:127665584(-) A-G intron -    22484847 chr9:127680301(-) A-G intron -    22484847 chr9:127686208(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GOLGA1	chr9:127641497-127641498(-) m6A 3'UTR       27773535 chr9:127641539-127641540(-) m6A 3'UTR       27773535 chr9:127641583-127641584(-) m6A 3'UTR       27773535 chr9:127641621-127641622(-) m6A 3'UTR       27773535 chr9:127641766-127641767(-) m6A 3'UTR       27773535 chr9:127642071-127642072(-) m6A 3'UTR       27773535 chr9:127642081-127642082(-) m6A 3'UTR       27773535 chr9:127642150-127642151(-) m6A 3'UTR       27773535 chr9:127642170-127642171(-) m6A 3'UTR       27773535 chr9:127642255-127642256(-) m6A 3'UTR       24284625//24981863//27773535 chr9:127642265-127642266(-) m6A 3'UTR       24284625//24981863//27773535 chr9:127642356-127642357(-) m6A 3'UTR       27773535//27371828 chr9:127642374-127642375(-) m6A 3'UTR       27773535//27371828 chr9:127642395-127642396(-) m6A 3'UTR       27773535//27371828 chr9:127642753-127642754(-) m6A 3'UTR       24981863 chr9:127642802-127642803(-) m6A 3'UTR       24981863 chr9:127650562-127650563(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650567-127650568(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650620-127650621(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650652-127650653(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651479-127651480(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651522-127651523(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651760-127651761(-) m6A 3'UTR//CDS       24981863//27773535//27371828 chr9:127651779-127651780(-) m6A 3'UTR//CDS       24981863//27773535//27371828 chr9:127660842-127660843(-) m6A 3'UTR//CDS       24209618//24981863//27773535//27371828 chr9:127660920-127660921(-) m6A 3'UTR//CDS       24209618//27773535//27371828 chr9:127661627-127661628(-) m6A 3'UTR//CDS       24209618//27773535//27371828 chr9:127662807-127662808(-) m6A 3'UTR//CDS//exon       27773535 chr9:127662817-127662818(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670660-127670661(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670715-127670716(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670747-127670748(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr9:127674191-127674192(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr9:127674203-127674204(-) m6A 3'UTR//CDS       24981863//27773535 chr9:127674219-127674220(-) m6A 3'UTR//CDS       27773535 chr9:127674224-127674225(-) m6A 3'UTR//CDS       27773535 chr9:127674230-127674231(-) m6A 3'UTR//CDS       27773535 chr9:127674292-127674293(-) m6A 3'UTR//CDS       24981863//27773535 chr9:127683455-127683456(-) m6A CDS//intron       24981863 chr9:127683464-127683465(-) m6A CDS//intron       24981863 chr9:127683496-127683497(-) m6A CDS//intron       24981863 chr9:127684027-127684028(-) m6A CDS       24981863//27773535 chr9:127684058-127684059(-) m6A CDS       24981863//27773535 chr9:127684079-127684080(-) m6A CDS       24981863//27773535 chr9:127684108-127684109(-) m6A CDS       24981863//27773535 chr9:127684116-127684117(-) m6A CDS       24981863//27773535 chr9:127684135-127684136(-) m6A CDS       24981863//27773535 chr9:127685394-127685395(-) m6A CDS       27773535 chr9:127685461-127685462(-) m6A CDS       27773535 chr9:127690470-127690471(-) m6A CDS       27773535 chr9:127690496-127690497(-) m6A CDS       27773535 chr9:127690531-127690532(-) m6A CDS       24981863//27773535 chr9:127691504-127691505(-) m6A CDS       24981863 chr9:127705398-127705399(-) m6A intron       - chr9:127708250-127708251(-) m6A intron       27773535 chr9:127708338-127708339(-) m6A intron       27773535 chr9:127710154-127710155(-) m6A exon//intron       24981863 chr9:127710212-127710213(-) m6A 5'UTR//exon       24981863 chr9:127710221-127710222(-) m6A 5'UTR//exon       24981863 chr9:127710248-127710249(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-223-5p	Exosome Primary dendritic cells     21505438 Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	GOLGA1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-223-5p
Interactor2: GOLGA1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.