Basic Information:

  VIRBase ID:  

HHID00053219

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-185-5p:  MIMAT0000455          NPAT:  NM_001321307     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-185-5p	NPAT
miRBase Accession/Entrez ID	MIMAT0000455	4863
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	E14//E14/NPAT//p220

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-185-5p	rs1249170072 chr22:20033164    G/A rs770235403 chr22:20033168    T/C rs775856637 chr22:20033173    G/A rs1398989482 chr22:20033154    G/A rs761385932 chr22:20033159    GAA/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NPAT	chr11:108052068(-) A-I      intronic chr11:108049578(-) A-I      intronic chr11:108048626(-) A-I      intronic chr11:108036947(-) A-I      intronic chr11:108031424(-) A-I      intronic chr11:108058126(-) A-I      intronic chr11:108058129(-) A-I      intronic chr11:108031449(-) A-I      intronic chr11:108031457(-) A-I      intronic chr11:108058132(-) A-I      intronic chr11:108058133(-) A-I      intronic chr11:108058135(-) A-I      intronic chr11:108058141(-) A-I      intronic chr11:108058143(-) A-I      intronic chr11:108082213(-) A-I      intronic chr11:108082012(-) A-I      intronic chr11:108081802(-) A-I      intronic chr11:108058127(-) A-I      intronic chr11:108056904(-) A-I      intronic chr11:108052071(-) A-I      intronic chr11:108048667(-) A-I      intronic chr11:108048651(-) A-I      intronic chr11:108048625(-) A-I      intronic chr11:108048623(-) A-I      intronic chr11:108079301(-) A-I      intronic chr11:108048090(-) A-I      intronic chr11:108048006(-) A-I      intronic chr11:108058079(-) A-I      intronic chr11:108053912(-) A-I      intronic chr11:108053839(-) A-I      intronic chr11:108053822(-) A-I      intronic chr11:108079171(-) A-I      intronic chr11:108088711(-) A-I      intronic chr11:108088598(-) A-I      intronic chr11:108088535(-) A-I      intronic chr11:108048005(-) A-I      intronic chr11:108036971(-) A-I      intronic chr11:108084911(-) A-I      intronic chr11:108084889(-) A-I      intronic chr11:108084887(-) A-I      intronic chr11:108036110(-) A-I      intronic chr11:108084712(-) A-I      intronic chr11:108084707(-) A-I      intronic chr11:108055009(-) A-I      intronic chr11:108084676(-) A-I      intronic chr11:108076116(-) A-I      intronic chr11:108035747(-) A-I      intronic chr11:108053738(-) A-I      intronic chr11:108053463(-) A-I      intronic chr11:108035656(-) A-I      intronic chr11:108088528(-) A-I      intronic chr11:108036455(-) A-I      intronic chr11:108036425(-) A-I      intronic chr11:108053369(-) A-I      intronic chr11:108035655(-) A-I      intronic chr11:108053365(-) A-I      intronic chr11:108035651(-) A-I      intronic chr11:108055554(-) A-I      intronic chr11:108055288(-) A-I      intronic chr11:108082537(-) A-I      intronic chr11:108053362(-) A-I      intronic chr11:108053267(-) A-I      intronic chr11:108082527(-) A-I      intronic chr11:108053330(-) A-I      intronic chr11:108082511(-) A-I      intronic chr11:108055017(-) A-I      intronic chr11:108079289(-) A-I      intronic chr11:108082663(-) A-I      intronic chr11:108037036(-) A-I      intronic chr11:108079220(-) A-I      intronic chr11:108079214(-) A-I      intronic chr11:108035638(-) A-I      intronic chr11:108035494(-) A-I      intronic chr11:108048113(-) A-I      intronic chr11:108079203(-) A-I      intronic chr11:108079197(-) A-I      intronic chr11:108079193(-) A-I      intronic chr11:108079112(-) A-I      intronic chr11:108079101(-) A-I      intronic chr11:108076672(-) A-I      intronic chr11:108076066(-) A-I      intronic chr11:108048132(-) A-I      intronic chr11:108050239(-) A-I      intronic chr11:108051008(-) A-I      intronic chr11:108076578(-) A-I      intronic chr11:108076152(-) A-I      intronic chr11:108054446(-) A-I      intronic chr11:108084793(-) A-I      intronic chr11:108076148(-) A-I      intronic chr11:108065509(-) A-I      intronic chr11:108054311(-) A-I      intronic chr11:108049359(-) A-I      intronic chr11:108057023(-) A-I      intronic chr11:108076203(-) A-I      intronic chr11:108048531(-) A-I      intronic chr11:108048572(-) A-I      intronic chr11:108056882(-) A-I      intronic chr11:108056828(-) A-I      intronic chr11:108052116(-) A-I      intronic chr11:108049502(-) A-I      intronic chr11:108056812(-) A-I      intronic chr11:108056806(-) A-I      intronic chr11:108076770(-) A-I      intronic chr11:108079253(-) A-I      intronic chr11:108052025(-) A-I      intronic chr11:108048707(-) A-I      intronic chr11:108055075(-) A-I      intronic chr11:108055197(-) A-I      intronic chr11:108085632(-) A-I      intronic chr11:108054617(-) A-I      intronic chr11:108055155(-) A-I      intronic chr11:108079191(-) A-I      intronic chr11:108055090(-) A-I      intronic chr11:108052073(-) A-I      intronic chr11:108052028(-) A-I      intronic chr11:108055099(-) A-I      intronic chr11:108084854(-) A-I      intronic chr11:108082555(-) A-I      intronic chr11:108055077(-) A-I      intronic chr11:108082208(-) A-I      intronic chr11:108050852(-) A-I      intronic chr11:108054977(-) A-I      intronic chr11:108054576(-) A-I      intronic chr11:108054445(-) A-I      intronic chr11:108049340(-) A-I      intronic chr11:108079314(-) A-I      intronic chr11:108036499(-) A-I      intronic chr11:108053335(-) A-I      intronic chr11:108054366(-) A-I      intronic chr11:108049326(-) A-I      intronic chr11:108036979(-) A-I      intronic chr11:108054337(-) A-I      intronic chr11:108054284(-) A-I      intronic chr11:108048733(-) A-I      intronic chr11:108053995(-) A-I      intronic chr11:108048712(-) A-I      intronic chr11:108053965(-) A-I      intronic chr11:108054572(-) A-I      intronic chr11:108034034(-) A-I      intronic chr11:108079309(-) A-I      intronic chr11:108055087(-) A-I      intronic chr11:108036246(-) A-I      intronic chr11:108079134(-) A-I      intronic chr11:108082596(-) A-I      intronic chr11:108054578(-) A-I      intronic chr11:108049341(-) A-I      intronic chr11:108054600(-) A-I      intronic chr11:108076214(-) A-I      intronic chr11:108056976(-) A-I      intronic chr11:108079100(-) A-I      intronic chr11:108082146(-) A-I      intronic chr11:108036783(-) A-I      intronic chr11:108084809(-) A-I      intronic chr11:108082564(-) A-I      intronic chr11:108055550(-) A-I      intronic chr11:108052186(-) A-I      intronic chr11:108051946(-) A-I      intronic chr11:108050862(-) A-I      intronic chr11:108082264(-) A-I      intronic chr11:108076238(-) A-I      intronic chr11:108045444(-) A-I      intronic chr11:108075998(-) A-I      intronic chr11:108076663(-) A-I      intronic chr11:108076054(-) A-I      intronic chr11:108058097(-) A-I      intronic chr11:108054520(-) A-I      intronic chr11:108081824(-) A-I      intronic chr11:108055395(-) A-I      intronic chr11:108031446(-) A-I      intronic chr11:108052170(-) A-I      intronic chr11:108088644(-) A-I      intronic chr11:108054954(-) A-I      intronic chr11:108054009(-) A-I      intronic chr11:108036476(-) A-I      intronic chr11:108048178(-) A-I      intronic chr11:108053490(-) A-I      intronic chr11:108082528(-) A-I      intronic chr11:108066493(-) A-I      intronic chr11:108054272(-) A-I      intronic chr11:108065844(-) A-I      intronic chr11:108065514(-) A-I      intronic chr11:108076650(-) A-I      intronic chr11:108045525(-) A-I      intronic chr11:108080602(-) A-I      intronic chr11:108053972(-) A-I      intronic chr11:108050248(-) A-I      intronic chr11:108084693(-) A-I      intronic chr11:108049342(-) A-I      intronic chr11:108050083(-) A-I      intronic chr11:108084896(-) A-I      intronic chr11:108050882(-) A-I      intronic chr11:108050803(-) A-I      intronic chr11:108082565(-) A-I      intronic chr11:108030245(-) A-I      intronic chr11:108048532(-) A-I      intronic chr11:108050939(-) A-I      intronic chr11:108053913(-) A-I      intronic chr11:108084743(-) A-I      intronic chr11:108035594(-) A-I      intronic chr11:108048166(-) A-I      intronic chr11:108054356(-) A-I      intronic chr11:108036477(-) A-I      intronic chr11:108052109(-) A-I      intronic chr11:108055530(-) A-I      intronic chr11:108033250(-) A-I      intronic chr11:108063543(-) A-I      intronic chr11:108031445(-) A-I      intronic chr11:108079113(-) A-I      intronic chr11:108054588(-) A-I      intronic chr11:108036426(-) A-I      intronic chr11:108084869(-) A-I      intronic chr11:108056999(-) A-I      intronic chr11:108055372(-) A-I      intronic chr11:108053385(-) A-I      intronic chr11:108055185(-) A-I      intronic chr11:108049477(-) A-I      intronic chr11:108053836(-) A-I      intronic chr11:108076142(-) A-I      intronic chr11:108052019(-) A-I      intronic chr11:108035751(-) A-I      intronic chr11:108049517(-) A-I      intronic chr11:108082148(-) A-I      intronic chr11:108081780(-) A-I      intronic chr11:108084729(-) A-I      intronic chr11:108076567(-) A-I      intronic chr11:108050824(-) A-I      intronic chr11:108053933(-) A-I      intronic chr11:108037085(-) A-I      intronic chr11:108035686(-) A-I      intronic chr11:108049328(-) A-I      intronic chr11:108055034(-) A-I      intronic chr11:108031467(-) A-I      intronic chr11:108055331(-) A-I      intronic chr11:108035547(-) A-I      intronic chr11:108088714(-) A-I      intronic chr11:108036018(-) A-I      intronic chr11:108036997(-) A-I      intronic chr11:108051934(-) A-I      intronic chr11:108054943(-) A-I      intronic chr11:108036989(-) A-I      intronic chr11:108035755(-) A-I      intronic chr11:108055531(-) A-I      intronic chr11:108050809(-) A-I      intronic chr11:108046733(-) A-I      intronic chr11:108037019(-) A-I      intronic chr11:108050932(-) A-I      intronic chr11:108085633(-) A-I      intronic chr11:108055136(-) A-I      intronic chr11:108036785(-) A-I      intronic chr11:108065488(-) A-I      intronic chr11:108048734(-) A-I      intronic chr11:108082126(-) A-I      intronic chr11:108082674(-) A-I      intronic chr11:108036589(-) A-I      intronic chr11:108053993(-) A-I      intronic chr11:108054429(-) A-I      intronic chr11:108050836(-) A-I      intronic chr11:108082673(-) A-I      intronic chr11:108076070(-) A-I      intronic chr11:108082057(-) A-I      intronic chr11:108088637(-) A-I      intronic chr11:108036475(-) A-I      intronic chr11:108031507(-) A-I      intronic chr11:108050959(-) A-I      intronic chr11:108084683(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NPAT	chr11:108031446(-) A-I intron -    22327324 chr11:108079083(-) A-I intron -    21960545 chr11:108079265(-) A-I intron -    21960545 chr11:108029109(-) A-T exon 3'UTR    21725310 chr11:108031445(-) A-G intron -    22484847 chr11:108031446(-) A-G intron -    22484847 chr11:108083345(-) C-T intron -    22484847 chr11:108048113(-) A-G intron -    22484847 chr11:108048707(-) A-G intron -    22484847 chr11:108048734(-) A-G intron -    22484847 chr11:108049477(-) A-G intron -    22484847 chr11:108050803(-) A-G intron -    22484847 chr11:108050809(-) A-G intron -    22484847 chr11:108052116(-) A-G intron -    22484847 chr11:108055372(-) A-G intron -    22484847 chr11:108082596(-) A-G intron -    22484847 chr11:108082674(-) A-G intron -    22484847 chr11:108084854(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NPAT	chr11:108029426-108029427(-) m6A 3'UTR//exon       27773535 chr11:108029493-108029494(-) m6A 3'UTR//exon       27773535//22608085 chr11:108029516-108029517(-) m6A 3'UTR//exon       27773535//22608085 chr11:108029551-108029552(-) m6A 3'UTR//exon       24981863//27773535//22608085 chr11:108029617-108029618(-) m6A 3'UTR//exon       24209618//24981863//26404942//27773535//22608085 chr11:108029632-108029633(-) m6A 3'UTR//exon       24209618//24981863//26404942//27773535//22608085 chr11:108029648-108029649(-) m6A 3'UTR//exon       24209618//24981863//26404942//27773535//22608085 chr11:108029658-108029659(-) m6A 3'UTR//exon       24209618//24981863//26404942//27773535//22608085 chr11:108029667-108029668(-) m6A 3'UTR//exon       24209618//24981863//26404942//27773535//22608085 chr11:108029702-108029703(-) m6A CDS//exon       24981863//27773535//22608085 chr11:108031670-108031671(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085 chr11:108031776-108031777(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085 chr11:108031835-108031836(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085 chr11:108031848-108031849(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr11:108031877-108031878(-) m6A CDS//exon//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr11:108031919-108031920(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085 chr11:108031966-108031967(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085 chr11:108031978-108031979(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085 chr11:108032004-108032005(-) m6A CDS//exon//intron       24284625//24981863//26404942//27773535//22608085 chr11:108032113-108032114(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chr11:108032119-108032120(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chr11:108032165-108032166(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chr11:108032182-108032183(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chr11:108032257-108032258(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032281-108032282(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032382-108032383(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032488-108032489(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032552-108032553(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032573-108032574(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108032641-108032642(-) m6A CDS//exon       22608085 chr11:108042936-108042937(-) m6A CDS//exon       27773535 chr11:108042972-108042973(-) m6A CDS//exon       24284625//27773535//22608085 chr11:108042988-108042989(-) m6A CDS//exon       24284625//27773535//22608085 chr11:108043072-108043073(-) m6A CDS//exon       24284625//24981863//27773535//22575960//22608085 chr11:108043236-108043237(-) m6A CDS//exon       24284625//22608085 chr11:108043248-108043249(-) m6A CDS//exon       24284625//24981863//26404942//22608085 chr11:108043277-108043278(-) m6A CDS//exon       24284625//24981863//26404942//22608085 chr11:108043327-108043328(-) m6A CDS//exon       24284625//24981863//26404942//22608085 chr11:108043355-108043356(-) m6A CDS//exon       24284625//24981863//26404942//22608085 chr11:108043410-108043411(-) m6A CDS//exon       24284625//24209618//24981863//26404942//22608085 chr11:108043445-108043446(-) m6A CDS//exon       24284625//24981863//26404942//22608085 chr11:108043541-108043542(-) m6A CDS//exon       24284625//24981863//22608085 chr11:108043620-108043621(-) m6A CDS//exon       24284625//22608085 chr11:108044033-108044034(-) m6A CDS//exon       24981863//27773535//22608085 chr11:108044142-108044143(-) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chr11:108044247-108044248(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr11:108044275-108044276(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085 chr11:108044405-108044406(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr11:108044422-108044423(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr11:108044475-108044476(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108044483-108044484(-) m6A CDS//exon       24284625//24981863//27773535//22608085 chr11:108046984-108046985(-) m6A CDS//exon       27773535 chr11:108047014-108047015(-) m6A CDS//exon       27773535 chr11:108047095-108047096(-) m6A CDS//exon       27773535 chr11:108047758-108047759(-) m6A CDS//exon       27773535 chr11:108047768-108047769(-) m6A CDS//exon       27773535 chr11:108047772-108047773(-) m6A CDS//exon       27773535 chr11:108047782-108047783(-) m6A CDS//exon       27773535 chr11:108055964-108055965(-) m6A CDS//exon       27773535 chr11:108055987-108055988(-) m6A CDS//exon       27773535 chr11:108093349-108093350(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-185-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Plasma     29130611 Exosome Primary dendritic cells|T cell line (J77)     21505438 Exosome Breast milk     22211110 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Serum     25135963 Exosome Blood|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	NPAT	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-185-5p	7-Epi-10-deacetylbaccatin III 9872117 Drug sensitive Midostaurin 9829523 Drug resistant Tiotixene 941651 Drug sensitive Acridine Yellow G 8672 Drug resistant 1,9-Pyrazoloanthrone 8515 Drug resistant Pingyangmycin 84046 Drug resistant Tanakan 83818 Drug sensitive 2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive Secalonic acid D 73431 Drug sensitive Coptisine chloride 72321 Drug sensitive 7-Hydroxystaurosporine 72271 Drug resistant Anaxirone 71218 Drug resistant Dihydroxydiphenyl-pyridyl methane 69046 Drug resistant Mevastatin 64715 Drug resistant Everolimus 6442177 Drug resistant Primaquine phosphate 6135 Drug sensitive 1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive 8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive Thiopyrimidine-CH3 5473238 Drug sensitive Iejimalide A. 5473233 Drug sensitive 11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant 6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive Bleomycin 5460769 Drug resistant Herveline O 5459269 Drug sensitive [2-[2-[(1R,2S)-2-[[6-Amino-2-[1-[(2S)-2,3-diamino-3-oxopropyl]-4-oxoazetidin-2-yl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S,4S)-3-hydroxy-5-[[(2S,3R)-3-hydroxy-1-[2-[4-[4-[2-(2-hydroxypropylamino)ethylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-1-oxobutan-2-yl]amino]-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate 5458321 Drug resistant Melampodin B acetate 5359212 Drug sensitive 5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive Lovastatin 53232 Drug resistant Cytochalasin B 5311281 Drug resistant Herbimycin 5311102 Drug sensitive 5-Fluoro-2'-deoxycytidine 515328 Drug resistant Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive Staurosporine, 98% 49831000 Drug resistant 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 4713 Drug sensitive Methyl (13S,15S,16R,18S)-13-[(10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-10-methoxycarbonyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-18-ethyl-1-oxido-17-oxa-11-aza-1-azoniapentacyclo[13.4.1.04,12.05,10.016,18]icosa-4(12),5,7,9-tetraene-13-carboxylate 462173 Drug sensitive 3-3'-(1H-Pyrazole-3,5-diyl)bis(1-methyl-1H-indole) 44433919 Drug resistant 4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Bleomycin-BAPP 431594 Drug resistant Bleomycin A5, sulfate 422920 Drug resistant Aminopyrimidine-CH3 406278 Drug sensitive 1H-Naphth[2,3-d]imidazole, 2-[(4-chlorophenyl)methyl]- 405626 Drug resistant Purpureagitosid 401298 Drug resistant Trapoxin B 395803 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive 5,8-Dihydroxy-2-(4-(2-pyridinyl)-1-piperazinyl)naphthoquinone 376947 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant 2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant 1-(4-Methoxy-2-methylphenyl)naphtho[1,2-c]furan-3(1H)-one 369148 Drug sensitive 3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive 2,7-Dicyanoxanthone 363841 Drug sensitive Girolline 362388 Drug resistant 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive 7alpha-Acetoxyroylenane 362048 Drug sensitive Thiosangivamycin 3580213 Drug sensitive Imidazole, 1-(4-chlorophenyl)-4-(4-nitrophenyl)- 355940 Drug resistant 2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive 1,4-Diaminoanthraquinone 31420 Drug resistant Clomifene citrate 3033832 Drug sensitive SMA-491 (free base of NSC D742838) 302576 Drug resistant Gardenin A 261859 Drug resistant Hookerianamide J 25016666 Drug sensitive Hookerianamide K 25016412 Drug sensitive (2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive CID 24197685 24197685 Drug sensitive Antibiotic U 29135 24196291 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive Kinetin riboside 20345 Drug resistant Chonemorphine 165208 Drug sensitive (6R)-1,6,11-Trihydroxy-8-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-[(2S,4R,5R,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3-methyl-5,6-dihydrobenzo[a]anthracene-7,12-dione 15507920 Drug sensitive Ellipticine analog 148569 Drug resistant (2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive Astrazon Orange R 135747272 Drug sensitive [(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant Methyl (1S,10R,11S,12S)-11-acetyloxy-12-ethyl-4-[(13R,15R,17R)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 133126830 Drug sensitive (2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive 1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant Pepleo 122804 Drug resistant Cyanoaminopyranopyridine derivatives 11494577 Drug resistant 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant Acetylenedicarboxamide 10971 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive Binimetinib 10288191 Drug sensitive (1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive Selumetinib 10127622 Drug sensitive 1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant 1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug resistant 6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant 3-peg fudr (peg floxuridine) - Drug resistant 6-aryl alkyl fluoro quinolone derivative - Drug resistant Annamycin Liposomal - Drug resistant antineoplastic-d655481 - Drug resistant Camptothecin Derivative - Drug resistant geldanamycin dimethylglycinate - Drug resistant organosulfur compound - Drug resistant tartrolon a1 - Drug resistant toxin .delta.53l - Drug resistant tp4ek - Drug resistant viridomycin - Drug resistant (z) 3,3',4,5-tetramethoxystilbene - Drug sensitive 1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive 1-piperidinecarbodithioic acid, antimony complex - Drug sensitive 2-azabicyclo[16.3.1]docosane, geldanamycin deriv. - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive (Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive 1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive 5-hydroxyamino camptothecin - Drug sensitive antineoplastic-615538 - Drug sensitive dichlorobisoxinatotitanium(iv) - Drug sensitive geldanamycin deriv - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive xenorhabdin 1 - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-185-5p	Formaldehyde 712 Drug interaction    RC00003208 Oxaliplatine 6857599 Drug interaction    RC00003218 Gemcitabine 60750 Drug interaction    RC00003213 Cholesterol 5997 Drug interaction    RC00003211 Eloxatine 5310940 Drug interaction    RC00003217 Decitabine 451668 Drug interaction    RC00003215 5-Fluorouracil 3385 Drug interaction    RC00003210 Doxorubicin 31703 Drug interaction    RC00003212 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003209 Tamoxifen 2733526 Drug interaction    RC00003216 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00003219 Benzene 241 Drug interaction    RC00003207 Leucovorin 135403648 Drug interaction    RC00003220

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-185-5p	Cisplatin 5702198       27906433 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-185-5p
Interactor2: NPAT

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.