Basic Information
RNALocate ID: RLID:00012614
RNA Symbol: NPAT
Localization: Ribosome-free cytosol
Localization from RNA-seq Dataset:  
RNA Information
RNA Name: NPAT
RNA ID: NCBI:4863|Ensembl:ENSG00000149308
RNA Category: mRNA
Species: Homo sapiens
Alias: E14|E14/NPAT|p220
Sequence:
Localization Information
PubMed ID: 24393600
Tissue/Cell Line: Colon cancer cells
Method: Next-generation RNA sequencing
Description: The RNA composition of the subcellular fractions differs significantly from each other, but lncRNAs are found in all locations. A subset of specific lncRNAs is enriched in the nucleus but surprisingly the majority is enriched in the cytosol and in ribosomal fractions. The ribosomal enriched lncRNAs include H19 and TUG1. Most studies on lncRNAs have focused on the regulatory function of these transcripts in the nucleus. We demonstrate that only a minority of all lncRNAs are nuclear enriched. Our findings suggest that many lncRNAs may have a function in cytoplasmic processes, and in particular in ribosome complexes. Data were collected from additional file 5.Overall, we consider clusters I, II and III as enriched in the nucleus; IV and V as enriched in the ribosome-free cytosol; and VI, VII, VIII, IX and X as enriched in the ribosomes.
Homology Information
RNA Symbol Gene ID Species Detail
Npat NCBI:244879 Mus musculus Go to
Other Subcellular Localization
RNALocate ID Localization Tissue/Cell line PubMed ID
RLID:00012613 Cytosol Human myelogenous leukemia cell line (K-562) 21613539
RLID-D:00003349 Chromatin K562 cells
RLID-D:00010464 Cytosol HCC cell line (HepG2)|K562 cells
RLID-D:00021113 Nucleolus K562 cells
RLID-D:00027713 Nucleoplasm K562 cells
RLID-D:00035872 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells
RLID-D:10009014 Exosome Blood
RNA Interaction Information
Resource RNA Symbol Species Link RNALocate ID
RNAInter hsa-miR-17-5p Homo sapiens RR01012701
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