Detail Information

Basic Information:


  VIRBase ID:  

HHID00044881

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-3p:           SH3GL1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-3p SH3GL1
miRBase
Accession/Entrez ID		 MIMAT0000088 6455
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CNSA1//EEN//SH3D2B//SH3P8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-3p
rs149150037 chr6:71403567    G/A
rs149150037 chr6:71403567    G/C
rs370184894 chr6:71403566    C/A
rs370184894 chr6:71403566    C/T
rs552541514 chr6:71403558    C/G
rs745605208 chr6:71403563    ATCCG/A
rs746505574 chr6:71403557    G/A
rs746505574 chr6:71403557    G/T
rs746965145 chr6:71403554    GCT/G
rs750918072 chr6:71403564    T/C
rs765735953 chr6:71403560    A/T
rs770865356 chr6:71403559    A/AC
rs776574456 chr6:71403560    A/AAGCTGGAGT
rs368070339 chr6:71403571    G/A
rs769702885 chr6:71403570    TG/T
rs775921090 chr6:71403574    AGCC/A
rs781617967 chr6:71403573    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SH3GL1
chr19:4377391(-) A-I      intronic
chr19:4377414(-) A-I      intronic
chr19:4377461(-) A-I      intronic
chr19:4377447(-) A-I      intronic
chr19:4377426(-) A-I      intronic
chr19:4398012(-) A-I      intronic
chr19:4398013(-) A-I      intronic
chr19:4398601(-) A-I      intronic
chr19:4377345(-) A-I      intronic
chr19:4376336(-) A-I      intronic
chr19:4396284(-) A-I      intronic
chr19:4399260(-) A-I      intronic
chr19:4387953(-) A-I      intronic
chr19:4398564(-) A-I      intronic
chr19:4398620(-) A-I      intronic
chr19:4398573(-) A-I      intronic
chr19:4398566(-) A-I      intronic
chr19:4384880(-) A-I      intronic
chr19:4384842(-) A-I      intronic
chr19:4381822(-) A-I      intronic
chr19:4384969(-) A-I      intronic
chr19:4381766(-) A-I      intronic
chr19:4398563(-) A-I      intronic
chr19:4398517(-) A-I      intronic
chr19:4398508(-) A-I      intronic
chr19:4398465(-) A-I      intronic
chr19:4398063(-) A-I      intronic
chr19:4397982(-) A-I      intronic
chr19:4397955(-) A-I      intronic
chr19:4397882(-) A-I      intronic
chr19:4399151(-) A-I      intronic
chr19:4379301(-) A-I      intronic
chr19:4396168(-) A-I      intronic
chr19:4387978(-) A-I      intronic
chr19:4396268(-) A-I      intronic
chr19:4396149(-) A-I      intronic
chr19:4395746(-) A-I      intronic
chr19:4392900(-) A-I      intronic
chr19:4392770(-) A-I      intronic
chr19:4388052(-) A-I      intronic
chr19:4387995(-) A-I      intronic
chr19:4387972(-) A-I      intronic
chr19:4387114(-) A-I      intronic
chr19:4386581(-) A-I      intronic
chr19:4384989(-) A-I      intronic
chr19:4384929(-) A-I      intronic
chr19:4388051(-) A-I      intronic
chr19:4379311(-) A-I      intronic
chr19:4398137(-) A-I      intronic
chr19:4399270(-) A-I      intronic
chr19:4398043(-) A-I      intronic
chr19:4379315(-) A-I      intronic
chr19:4384979(-) A-I      intronic
chr19:4388128(-) A-I      intronic
chr19:4381818(-) A-I      intronic
chr19:4392511(-) A-I      intronic
chr19:4387031(-) A-I      intronic
chr19:4372078(-) A-I      intronic
chr19:4387002(-) A-I      intronic
chr19:4387072(-) A-I      intronic
chr19:4385019(-) A-I      intronic
chr19:4399154(-) A-I      intronic
chr19:4399096(-) A-I      intronic
chr19:4386608(-) A-I      intronic
chr19:4381828(-) A-I      intronic
chr19:4388040(-) A-I      intronic
chr19:4392358(-) A-I      intronic
chr19:4387835(-) A-I      intronic
chr19:4385062(-) A-I      intronic
chr19:4385001(-) A-I      intronic
chr19:4388022(-) A-I      intronic
chr19:4398504(-) A-I      intronic
chr19:4399230(-) A-I      intronic
chr19:4387001(-) A-I      intronic
chr19:4384938(-) A-I      intronic
chr19:4383001(-) A-I      intronic
chr19:4383088(-) A-I      intronic
chr19:4387942(-) A-I      intronic
chr19:4398026(-) A-I      intronic
chr19:4385025(-) A-I      intronic
chr19:4399217(-) A-I      intronic
chr19:4387819(-) A-I      intronic
chr19:4396360(-) A-I      intronic
chr19:4386943(-) A-I      intronic
chr19:4396274(-) A-I      intronic
chr19:4397878(-) A-I      intronic
chr19:4384977(-) A-I      intronic
chr19:4397972(-) A-I      intronic
chr19:4397946(-) A-I      intronic
chr19:4384844(-) A-I      intronic
chr19:4384928(-) A-I      intronic
chr19:4398505(-) A-I      intronic
chr19:4387981(-) A-I      intronic
chr19:4387098(-) A-I      intronic
chr19:4385015(-) A-I      intronic
chr19:4392894(-) A-I      intronic
chr19:4383447(-) A-I      intronic
chr19:4385018(-) A-I      intronic
chr19:4392469(-) A-I      intronic
chr19:4387832(-) A-I      intronic
chr19:4364382(-) A-I      intronic
chr19:4383350(-) A-I      intronic
chr19:4399231(-) A-I      intronic
chr19:4392349(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SH3GL1
chr19:4362691(-) C-G exon CDS    21725310
chr19:4396781(-) A-G intron -    22484847
chr19:4396785(-) A-G intron -    22484847
chr19:4384918(-) A-G intron -    22484847
chr19:4385001(-) A-G intron -    22484847
chr19:4393366(-) G-A intron -    22484847
chr19:4398137(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SH3GL1
chr19:4360393-4360394(-) m6A 3'UTR       27773535
chr19:4360420-4360421(-) m6A 3'UTR       27773535
chr19:4360518-4360519(-) m6A 3'UTR       27773535
chr19:4360643-4360644(-) m6A 3'UTR       24284625//27773535
chr19:4360777-4360778(-) m6A 3'UTR       24284625//27773535//22575960
chr19:4360942-4360943(-) m6A 3'UTR       24284625//27773535
chr19:4360949-4360950(-) m6A 3'UTR       24284625//27773535
chr19:4360977-4360978(-) m6A 3'UTR       24284625//27773535
chr19:4361136-4361137(-) m6A 3'UTR       27773535
chr19:4361444-4361445(-) m6A 3'UTR       24284625
chr19:4361678-4361679(-) m6A CDS       24284625//27371828//27773536//22575960
chr19:4361745-4361746(-) Gm CDS       -
chr19:4361783-4361784(-) m6A CDS       24284625//27773535//27371828//27773536//22575960
chr19:4362343-4362344(-) m6A CDS       24284625//27773535//27371828//27773536//22575960
chr19:4362361-4362362(-) Tm CDS       -
chr19:4363423-4363424(-) m6A CDS       24284625//24981863//27773535//27371828//27773536//22575960
chr19:4363721-4363722(-) m6A CDS       24284625//24981863//27371828//27773536//22575960
chr19:4363745-4363746(-) m6A CDS       24284625//24981863//27371828//27773536//22575960
chr19:4363840-4363841(-) m6A CDS       24284625//24981863//27773535//27371828//27773536//22575960
chr19:4363860-4363861(-) m6A CDS       24284625//27773535//27371828//27773536//22575960
chr19:4364100-4364101(-) m6A CDS       24284625//27773535//27371828//27773536//22575960
chr19:4364115-4364116(-) m6A CDS       24284625//27773535//27371828//27773536//22575960
chr19:4364136-4364137(-) m6A CDS//intron       24284625//27773535//27371828//27773536//22575960
chr19:4364154-4364155(-) m6A CDS//intron       24284625//27773535//27371828//27773536//22575960
chr19:4364163-4364164(-) m6A CDS//intron       24284625//24209618//27773535//27371828//27773536//22575960
chr19:4365561-4365562(-) m6A CDS//intron       24284625//24209618//27773535//27371828//27773536//22575960
chr19:4366524-4366525(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//27773536
chr19:4366957-4366958(-) m6A 5'UTR//CDS       24209618//24981863//27773535//27371828//22575960
chr19:4380184-4380185(-) m1A 5'UTR//intron       26863196//26863410
chr19:4380225-4380226(-) m6A 5'UTR//intron       24209618//27773535//27371828//22575960
chr19:4380244-4380245(-) m6A 5'UTR//intron       24209618
chr19:4395978-4395979(-) m6A 5'UTR//intron       24209618
chr19:4400343-4400344(-) m1A CDS       26863196//26863410
chr19:4400450-4400451(-) m6A 5'UTR       24209618//27371828//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-3p
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Endothelial cells|Epithelial cells|Tongue tissue     -
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Serum     24797360
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
SH3GL1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-3p
Sorafenib 216239 Drug interaction    RC00000903
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-3p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-3p
Interactor2: SH3GL1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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