Detail Information

Basic Information:


  VIRBase ID:  

HHID00024736

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-379-3p:           PTGS2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-379-3p PTGS2
miRBase
Accession/Entrez ID		 MIMAT0004690 5743
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - COX-2//COX2//GRIPGHS//hCox-2//PGG/HS//PGHS-2//PHS-2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-379-3p
rs1267644677 chr14:101022128    ACT/A
rs1376071062 chr14:101022117    A/G
rs1416546339 chr14:101022126    T/C
rs996338461 chr14:101022128    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PTGS2
chr1:186642926(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PTGS2
chr1:186641681-186641682(-) m6A 3'UTR       26404942
chr1:186641696-186641697(-) m6A 3'UTR       26404942
chr1:186641834-186641835(-) m6A 3'UTR       26404942
chr1:186641839-186641840(-) m6A 3'UTR       26404942
chr1:186641907-186641908(-) m6A 3'UTR       26404942
chr1:186642069-186642070(-) m6A 3'UTR//exon       26404942
chr1:186642082-186642083(-) m6A 3'UTR//exon       26404942
chr1:186643408-186643409(-) m6A 3'UTR//exon       24981863//26404942
chr1:186643450-186643451(-) m6A 3'UTR//exon       24981863//26404942
chr1:186643490-186643491(-) m6A 3'UTR//CDS//exon       24981863//26404942
chr1:186643538-186643539(-) m6A 3'UTR//CDS//exon       24981863//26404942
chr1:186643573-186643574(-) m6A 3'UTR//CDS//exon       24981863//26404942
chr1:186643742-186643743(-) m6A 3'UTR//CDS//exon       24981863//26404942
chr1:186643780-186643781(-) m6A 3'UTR//CDS//exon       24981863//26404942
chr1:186644387-186644388(-) m6A 3'UTR//CDS//exon       26404942
chr1:186644996-186644997(-) m6A exon//intron       26404942
chr1:186645080-186645081(-) m6A 3'UTR//CDS//exon       26404942
chr1:186645221-186645222(-) m6A 3'UTR//CDS//exon       26404942
chr1:186645236-186645237(-) m6A 3'UTR//CDS//exon       26404942
chr1:186645254-186645255(-) m6A 3'UTR//CDS//exon       26404942
chr1:186646000-186646001(-) m6A 3'UTR//CDS//exon       26404942
chr1:186646009-186646010(-) m6A 3'UTR//CDS//exon       26404942
chr1:186648287-186648288(-) m6A CDS//exon       26404942
chr1:186648298-186648299(-) m6A CDS//exon       26404942
chr1:186648464-186648465(-) m6A CDS//exon       26404942
chr1:186648483-186648484(-) m6A CDS//exon       26404942
chr1:186649464-186649465(-) m6A 5'UTR//exon       24981863//26404942
chr1:186649510-186649511(-) m6A 5'UTR//exon       24981863//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-379-3p
Exosome Saliva     19627513
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
PTGS2
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Polysome HeLa cells     26000482

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-379-3p
Interactor2: PTGS2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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